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Rothman 图：关联度量修饰与可折叠性的几何解释AI 解读

Here, we outline how Rothman diagrams provide a geometric perspective that can help epidemiologists understand the relationships between effect measure modification (which we call association measure modification), collapsibility, and confounding. A Rothman diagram plots the risk of disease in the unexposed on the x-axis and the risk in the exposed on the y-axis. Crude and stratum-specific risks in the two exposure groups define points in the unit square. When there is…

基于约束的因果学习：正确性条件的一般框架AI 解读

Most constraint-based causal learning algorithms provably return the correct causal graph under certain correctness conditions, such as faithfulness. By representing any constraint-based causal learning algorithm using the notion of a property, we provide a general framework to obtain and study correctness conditions for these algorithms. From the framework, we provide exact correctness conditions for the PC algorithm, which are then related to the correctness conditions of…

P-CRE-DML：非线性面板数据因果推断的新方法AI 解读

This paper introduces a novel Proxy-Enhanced Correlated Random Effects Double Machine Learning (P-CRE-DML) framework to estimate causal effects in panel data with non-linearities and unobserved heterogeneity. Combining Double Machine Learning (DML, Chernozhukov et al., 2018), Correlated Random Effects (CRE, Mundlak, 1978), and lagged variables (Arellano & Bond, 1991) and innovating within the CRE-DML framework (Chernozhukov et al., 2022; Clarke & Polselli, 2025; Fuhr &…

连续处理面板数据中的因果推断AI 解读

This paper proposes a framework that incorporates the two-way fixed effects model as a special case to conduct causal inference with a continuous treatment. Treatments are allowed to change over time and potential outcomes are dependent on historical treatments. Regression models on potential outcomes, along with the sequentially conditional independence assumptions (SCIAs) are introduced to identify the treatment effects, which are measured by aggre causal responses. Least…

地理断点设计的稳健推断：评估警察辖区的影响AI 解读

We study variation in policing outcomes attributable to differential policing practices in New York City (NYC) using geographic regression discontinuity designs (GeoRDDs). By focusing on small geographic windows near police precinct boundaries we can estimate local average treatment effects of police precinct practices on arrest rates. We propose estimands and develop estimators for the GeoRDD when the data come from a spatial point process. Standard GeoRDDs rely on…

协变量不可忽略缺失下最优动态治疗方案的稳健估计AI 解读

Estimating optimal dynamic treatment regimes (DTRs) using observational data is often challenged by nonignorable missing covariates arsing from informative monitoring of patients in clinical practice. To address nonignorable missingness of pseudo-outcomes induced by nonignorable missing covariates, a weighted Q-learning approach using parametric Q-function models and a semiparametric missingness propensity model has recently been proposed. However, misspecification of…

连续处理下随机对象结局因果效应的双重稳健估计AI 解读

Causal inference is central to statistics and scientific discovery, enabling researchers to identify cause-and-effect relationships beyond associations. While traditionally studied within Euclidean spaces, contemporary applications increasingly involve complex, non-Euclidean data structures that reside in abstract metric spaces, known as random objects, such as images, shapes, networks, and distributions. This paper introduces a novel framework for causal inference with…

动态因果效应中的非线性：如何改善负权重估计的解释？AI 解读

This paper was prepared as a comment on "Dynamic Causal Effects in a Nonlinear World: the Good, the Bad, and the Ugly" by Michal Kolesár and Mikkel Plagborg-Møller. We make three comments, including a novel contribution to the literature, showing how a reasonable economic interpretation can potentially be restored for average-effect estimators with negative weights.

定性结局的因果推断AI 解读

Causal inference methods such as instrumental variables, regression discontinuity, and difference-in-differences are widely used to identify and estimate treatment effects. However, when outcomes are qualitative, their application poses fundamental challenges. This paper highlights these challenges and proposes an alternative framework that focuses on well-defined and interpretable estimands. We show that conventional identification assumptions suffice for identifying the…

暴露与混杂变量不完整时的平均因果效应估计AI 解读

Standard methods for estimating average causal effects require complete observations of the exposure and confounders. In observational studies, however, missing data are ubiquitous. Motivated by a study on the effect of prescription opioids on mortality, we propose methods for estimating average causal effects when exposures and potential confounders may be missing. We consider missingness at random and additionally propose several specific missing not at random (MNAR)…

两阶段抽样下结局与处理均有测量误差的高效因果效应估计AI 解读

Measurement error is a common challenge for causal inference studies using electronic health record (EHR) data, where clinical outcomes and treatments are frequently mismeasured. Researchers often address measurement error by conducting manual chart reviews to validate measurements in a subset of the full EHR data -- a form of two-phase sampling. To improve efficiency, phase-two samples are often collected in a biased manner dependent on the patients' initial, error-prone…

通过条件独立关系以多项式延迟检验含隐变量的因果模型AI 解读

Testing a hypothesized causal model against observational data is a key prerequisite for many causal inference tasks. A natural approach is to test whether the conditional independence relations (CIs) assumed in the model hold in the data. While a model can assume exponentially many CIs (with respect to the number of variables), testing all of them is both impractical and unnecessary. Causal graphs, which encode these CIs in polynomial space, give rise to local Markov…

因子模型学习所得潜在结局的因果推断AI 解读

In many fields$\unicode{x2013}$including genomics, epidemiology, natural language processing, social and behavioral sciences, and economics$\unicode{x2013}$it is increasingly important to address causal questions in the context of factor models or representation learning. In this work, we investigate causal effects on $\textit{latent outcomes}$ derived from high-dimensional observed data using nonnegative matrix factorization. To the best of our knowledge, this is the first…

处理分配存在干扰时直接平均处理效应的稳健推断AI 解读

This paper develops methods for uncertainty quantification in causal inference settings with random network interference. We study the large-sample distributional properties of the classical difference-in-means Hajek treatment effect estimator, and propose a robust inference procedure for the (conditional) direct average treatment effect. Our framework allows for cross-unit interference in both the outcome equation and the treatment assignment mechanism. Drawing from…

在帮助有需要者的同时学习处理效应AI 解读

Many social programs attempt to allocate scarce resources to people with the greatest need. Indeed, public services increasingly use algorithmic risk assessments motivated by this goal. However, targeting the highest-need recipients often conflicts with attempting to evaluate the causal effect of the program as a whole, as the best evaluations would be obtained by randomizing the allocation. We propose a framework to design randomized allocation rules which optimally balance…

用 sPoRT 检查序贯正值性违背AI 解读

Background: Sequential positivity is often a necessary assumption for drawing causal inferences, such as through marginal structural modeling. Unfortunately, verification of this assumption can be challenging because it usually relies on multiple parametric propensity score models, unlikely all correctly specified. Therefore, we propose a new algorithm, called sequential Positivity Regression Tree (sPoRT), to overcome this issue and identify the subgroups found to be…

含暴露测量误差的灵活高效因果效应估计：控制变量法AI 解读

Exposure measurement error is a ubiquitous but often overlooked challenge in causal inference with observational data. Existing methods accounting for exposure measurement error largely rely on restrictive parametric assumptions, while emerging data-adaptive estimation approaches allow for less restrictive assumptions but at the cost of flexibility, as they are typically tailored towards rigidly-defined statistical quantities. There remains a critical need for…

基于 Transformer 的时空反事实结局估计AI 解读

The real world naturally has dimensions of time and space. Therefore, estimating the counterfactual outcomes with spatial-temporal attributes is a crucial problem. However, previous methods are based on classical statistical models, which still have limitations in performance and generalization. This paper proposes a novel framework for estimating counterfactual outcomes with spatial-temporal attributes using the Transformer, exhibiting stronger estimation ability. Under…

因果建模导论AI 解读

This tutorial provides a concise introduction to modern causal modeling by integrating potential outcomes and graphical methods. We motivate causal questions such as counterfactual reasoning under interventions and define binary treatments and potential outcomes. We discuss causal effect measures-including average treatment effects on the treated and on the untreated-and choices of effect scales for binary outcomes. We derive identification in randomized experiments under…

半竞争风险的贝叶斯非参数方法及心血管健康应用AI 解读

We address causal estimation in semi-competing risks settings, where a non-terminal event may be precluded by one or more terminal events. We define a principal-stratification causal estimand for treatment effects on the non-terminal event, conditional on surviving past a specified landmark time. To estimate joint event-time distributions, we employ both vine-copula constructions and Bayesian nonparametric Enriched Dirichlet-process mixtures (EDPM), enabling inference under…

确定性离散线性时不变微分代数系统中的因果发现AI 解读

Discovering pure causes or driver variables in deterministic LTI systems is of vital importance in the data-driven reconstruction of causal networks. A recent work by Kathari and Tangirala, proposed in 2022, formulated the causal discovery method as a constraint identification problem. The constraints are identified using a dynamic iterative PCA (DIPCA)-based approach for dynamical systems corrupted with Gaussian measurement errors. The DIPCA-based method works efficiently…

密集纵向数据的动态因果中介分析AI 解读

Intensive longitudinal data, characterized by frequent measurements across numerous time points, are increasingly common due to advances in wearable devices and mobile health technologies. We consider evaluating causal mediation pathways between time-varying exposures, time-varying mediators, and a final, distal outcome using such data. Addressing mediation questions in these settings is challenging due to numerous potential exposures, complex mediation pathways, and…

网络干扰下异质处理效应的随机化推断AI 解读

We develop randomization-based tests for heterogeneous treatment effects in the presence of network interference. Leveraging the exposure mapping framework, we study a broad class of null hypotheses that represent various forms of constant treatment effects in networked populations. These null hypotheses, unlike the classical Fisher sharp null, are not sharp due to unknown parameters and multiple potential outcomes. Existing conditional randomization procedures either fail…

底层有向混合图上的簇图：聚合层面因果效应识别AI 解读

The do-calculus is a sound and complete tool for identifying causal effects in acyclic directed mixed graphs (ADMGs) induced by structural causal models (SCMs). However, in many real-world applications, especially in high-dimensional setting, constructing a fully specified ADMG is often infeasible. This limitation has led to growing interest in partially specified causal representations, particularly through cluster-directed mixed graphs (C-DMGs), which group variables into…