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交叉验证因果推断：结合实验与观察数据的方法AI 解读

We develop new methods to integrate experimental and observational data in causal inference. While randomized controlled trials offer strong internal validity, they are often costly and therefore limited in sample size. Observational data, though cheaper and often with larger sample sizes, are prone to biases due to unmeasured confounders. To harness their complementary strengths, we propose a systematic framework that formulates causal estimation as an empirical risk…

基于距离协方差的估计量AI 解读

This paper proposes an estimator that relaxes the conventional relevance condition in instrumental variable (IV) analyses. The method allows endogenous covariates to be weakly correlated, uncorrelated, or even mean-independent -- though not independent -- of the instruments, enabling the use of the maximal set of relevant instruments in a given application. Identification is attainable without exclusion restrictions and without finite-moment assumptions on the disturbance…

基于随机化分布的稳健贝叶斯因果效应推断AI 解读

We present a general framework for Bayesian inference of causal effects that delivers provably robust inferences founded on design-based randomization of treatments. The framework involves fixing the observed potential outcomes and forming a likelihood based on the randomization distribution of a statistic. The method requires specification of a treatment effect model; in many cases, however, it does not require specification of marginal outcome distributions, resulting in…

污染下高维双重稳健因果推断的惩罚经验似然AI 解读

We propose a doubly robust estimator for the average treatment effect in high dimensional low sample size observational studies, where contamination and model misspecification pose serious inferential challenges. The estimator combines bounded influence estimating equations for outcome modeling with covariate balancing propensity scores for treatment assignment, embedded within a penalized empirical likelihood framework using nonconvex regularization. It satisfies the oracle…

高维非线性结果模型的残差平衡AI 解读

We extend the approximate residual balancing (ARB) framework to nonlinear models, answering an open problem posed by Athey et al. (2018). Our approach addresses the challenge of estimating average treatment effects in high-dimensional settings where the outcome follows a generalized linear model. We derive a new bias decomposition for nonlinear models that reveals the need for a second-order correction to account for the curvature of the link function. Based on this insight,…

随机实验中干扰效应的弱假设刻画AI 解读

We give an approach for characterizing interference by lower bounding the number of units whose outcome depends on selected groups of treated individuals, such as depending on the treatment of others, or others who are at least a certain distance away. The approach is applicable to randomized experiments with binary-valued outcomes. Asymptotically conservative point estimates and one-sided confidence intervals may be constructed with no assumptions beyond the known…

尖锐回归折点设计中局部处理效应识别与推断的统一框架AI 解读

This paper develops a unified framework for the identification, estimation, and uniform inference of local treatment effects (LTEs) in sharp regression kink designs (RKDs). These LTEs quantify the effect of a marginal change in the treatment at the kink point on various features of the outcome distribution. The identification strategy applies to Hadamard-differentiable functionals of the outcome distribution -- including means, quantiles, and inequality measures -- and…

因果推断的统一理论：通过 Bregman-Riesz 回归实现直接去偏机器学习AI 解读

This note introduces a unified theory for causal inference that integrates Riesz regression, covariate balancing, density-ratio estimation (DRE), targeted maximum likelihood estimation (TMLE), and the matching estimator in average treatment effect (ATE) estimation. In ATE estimation, the balancing weights and the regression functions of the outcome play important roles, where the balancing weights are referred to as the Riesz representer, bias-correction term, and clever…

通过最小化 Bregman 散度实现直接去偏机器学习AI 解读

We develop a direct debiased machine learning framework comprising Neyman targeted estimation and generalized Riesz regression. Our framework unifies Riesz regression for automatic debiased machine learning, covariate balancing, targeted maximum likelihood estimation (TMLE), and density-ratio estimation. In many problems involving causal effects or structural models, the parameters of interest depend on regression functions. Plugging regression functions estimated by machine…

结合时空建模与惩罚经验似然的预测型因果推断AI 解读

This study introduces an integrated framework for predictive causal inference designed to overcome limitations inherent in conventional single model approaches. Specifically, we combine a Hidden Markov Model (HMM) for spatial health state estimation with a Multi Task and Multi Graph Convolutional Network (MTGCN) for capturing temporal outcome trajectories. The framework asymmetrically treats temporal and spatial information regarding them as endogenous variables in the…

评估自适应风险预测模型临床影响的准实验设计AI 解读

Clinical risk prediction is a valuable tool for guiding healthcare interventions toward those most likely to benefit. Yet, evaluating the pairing of a risk prediction model with an intervention using randomized controlled trials presents substantial challenges, making quasi-experimental designs an attractive alternatives. Existing designs, however, assume that both the model and the decision rules used to trigger interventions (typically a risk threshold) remain fixed. This…

Chiseling：通过交互式机器学习选择子群并保证推断有效性AI 解读

In regression and causal inference, controlled subgroup selection aims to identify, with inferential guarantees, a subgroup (defined as a subset of the covariate space) on which the average response or treatment effect is above a given threshold. E.g., in a clinical trial, it may be of interest to find a subgroup with a positive average treatment effect. However, existing methods either lack inferential guarantees, heavily restrict the search for the subgroup, or sacrifice…

最优处理分配下福利与价值泛函的推断AI 解读

We provide theoretical results for the estimation and inference of a class of welfare and value functionals of the nonparametric conditional average treatment effect (CATE) function under optimal treatment assignment, i.e., treatment is assigned to an observed type if and only if its CATE is nonnegative. For the optimal welfare functional defined as the average value of CATE on the subpopulation with nonnegative CATE, we establish the $\sqrt{n}$ asymptotic normality of the…

数字健康干预中的可重复多臂老虎机算法AI 解读

Adaptive treatment assignment algorithms, such as bandit algorithms, are increasingly used in digital health intervention clinical trials. Frequently, the data collected from these trials is used to conduct causal inference and related data analyses to decide how to refine the intervention, and whether to roll-out the intervention more broadly. This work studies inference for estimands that depend on the adaptive algorithm itself; a simple example is the mean reward under…

存在不依从时的高效自适应实验AI 解读

We study the problem of estimating the average treatment effect (ATE) in adaptive experiments where treatment can only be encouraged -- rather than directly assigned -- via a binary instrumental variable. Building on semiparametric efficiency theory, we derive the efficiency bound for ATE estimation under arbitrary, history-dependent instrument-assignment policies, and show it is minimized by a variance-aware allocation rule that balances outcome noise and compliance…

机器学习辅助的回归函数比较AI 解读

We revisit the classical problem of comparing regression functions, a fundamental question in statistical inference with broad relevance to modern applications such as data integration, transfer learning, and causal inference. Existing approaches typically rely on smoothing techniques and are thus hindered by the curse of dimensionality. We propose a generalized notion of kernel-based conditional mean dependence that provides a new characterization of the null hypothesis of…

GST-UNet：处理时变混杂的时空因果推断神经框架AI 解读

Estimating causal effects from spatiotemporal observational data is essential in public health, environmental science, and policy evaluation, where randomized experiments are often infeasible. Existing approaches, however, either rely on strong structural assumptions or fail to handle key challenges such as interference, spatial confounding, temporal carryover, and time-varying confounding -- where covariates are influenced by past treatments and, in turn, affect future…

单阶段个体参与者数据元分析中治疗与协变量交互作用的不一致性度量AI 解读

It is recommended that measures of between-study effect heterogeneity be reported when conducting individual-participant data meta-analyses (IPD-MA). Methods exist to quantify inconsistency between trials via I^2 (the percentage of variation in the treatment effect due to between-study heterogeneity) when conducting two-stage IPD-MA, and when conducting one-stage IPD-MA with approximately equal numbers of treatment and control group participants. We extend formulae to…

样本选择下连续处理的 Lee 界限AI 解读

We study causal inference in sample selection models where a continuous or multivalued treatment affects both outcome and their observability (eg., employment or survey response). We generalized the widely used Lee (2009)'s bounds for binary treatment effects. Our key innovation is a sufficient treatment value assumption that imposes weak restrictions on selection heterogeneity and is implicit in separable threshold-crossing models, including monotone effects on selection.…

竞争事件下因果问题与统计方法错位的影响：以治疗机制为关注点AI 解读

In the presence of competing events, many investigators are interested in a direct treatment effect on the event of interest that does not capture treatment effects on competing events. Classical survival analysis methods that treat competing events like censoring events, at best, target a controlled direct effect: the effect of the treatment under a difficult to imagine and typically clinically irrelevant scenario where competing events are somehow eliminated. A separable…

Control VAR：基于反事实的宏观经济推断方法AI 解读

This paper addresses the challenges of giving a causal interpretation to vector autoregressions (VARs). I show that under independence assumptions VARs can identify average treatment effects, average causal responses, or a mix of the two, depending on the distribution of the policy. But what about situations in which the economist cannot rely on independence assumptions? I propose an alternative method, defined as control-VAR, which uses control variables to estimate causal…

基于分层的非线性效应工具变量分析框架AI 解读

Nonlinear causal effects are prevalent in many research scenarios involving continuous exposures, and instrumental variables (IVs) can be employed to investigate such effects, particularly in the presence of unmeasured confounders. However, common IV methods for nonlinear effect analysis, such as IV regression or the control-function method, have inherent limitations, leading to either low statistical power or potentially misleading conclusions. In this work, we propose an…

存在跨簇干扰的整群随机试验AI 解读

The literature on cluster-randomized trials typically allows for interference within but not across clusters. This may be implausible when units are irregularly distributed across space without well-separated communities, as clusters in such cases may not align with significant geographic, social, or economic divisions. This paper develops methods for reducing bias due to cross-cluster interference. We first propose an estimation strategy that excludes units not surrounded…

面板向量自回归的因果解释AI 解读

This paper discusses the different contemporaneous causal interpretations of Panel Vector Autoregressions (PVAR). I show that the interpretation of PVARs depends on the distribution of the causing variable, and can range from average treatment effects, to average causal responses, to a combination of the two. If the researcher is willing to postulate a no residual autocorrelation assumption, and some units can be thought of as controls, PVAR can identify average treatment…