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贝叶斯半参数因果推断：处理效应的目标化双重稳健估计AI 解读

We propose a semiparametric Bayesian methodology for estimating the average treatment effect (ATE) within the potential outcomes framework using observational data with high-dimensional nuisance parameters. Our method introduces a Bayesian debiasing procedure that corrects for bias arising from nuisance estimation and employs a targeted modeling strategy based on summary statistics rather than the full data. These summary statistics are identified in a debiased manner,…

交叉平衡：利用数据设计并高效分析观察研究AI 解读

Causal inference starts with a simple idea: compare groups that differ by treatment, not much else. Traditionally, similar groups are constructed using only observed covariates; however, it remains a long-standing challenge to incorporate available outcome data into the study design while preserving valid inference. In this paper, we study the general problem of covariate adjustment, effect estimation, and statistical inference when balancing features are constructed or…

通过张量补全推断序贯处理的因果效应AI 解读

Marginal Structural Models (MSMs) are popular for causal inference of sequential treatments in longitudinal observational studies, which however are sensitive to model misspecification. To achieve flexible modeling, we envision the potential outcomes to form a three-dimensional tensor indexed by subject, time, and treatment regime and propose a tensorized history-restricted MSM (HRMSM). The semi-parametric tensor factor model allows us to leverage the underlying low-rank…

稳健贝叶斯因果推断AI 解读

This paper develops a Bayesian framework for robust causal inference from longitudinal observational data. Many contemporary methods rely on structural assumptions, such as factor models, to adjust for unobserved confounding, but they can lead to biased causal estimands when mis-specified. We focus on directly estimating time--unit--specific causal effects and use generalised Bayesian inference to quantify model mis-specification and adjust for it, while retaining…

金融事件研究中的因果推断AI 解读

Financial event studies, ubiquitous in finance research, typically use linear factor models with known factors to estimate abnormal returns and identify causal effects of information events. This paper demonstrates that when factor models are misspecified -- an almost certain reality -- traditional event study estimators produce inconsistent estimates of treatment effects. The bias is particularly severe during volatile periods, over long horizons, and when event timing…

利用疫苗无关感染去偏随时间变化的风险率型疫苗效应AI 解读

Understanding how vaccine effectiveness (VE) changes over time can provide evidence-based guidance for public health decision making. While commonly reported by practitioners, time-varying VE estimates obtained using Cox regression are vul- nerable to hidden biases. To address these limitations, we describe how to leverage vaccine-irrelevant infections to identify hazard-based, time-varying VE in the pres- ence of unmeasured confounding and selection bias. We articulate…

连续处理因果推断中的个体化预测带AI 解读

Individualized treatments are crucial for optimal decision making and treatment allocation, specifically in personalized medicine based on the estimation of an individual's dose-response curve across a continuum of treatment levels, e.g., drug dosage. Current works focus on conditional mean and median estimates, which are useful but do not provide the full picture. We propose viewing causal inference with a continuous treatment as a covariate shift. This allows us to…

多协变量完全随机实验中的回归调整AI 解读

This paper investigates estimation and inference for average treatment effects in completely randomized experiments when researchers observe potentially many covariates. Within Neyman's (1923) design-based framework, allowing the number of covariates to grow more slowly than the sample size, we demonstrate that a cross-fitted regression adjustment estimator--adapted from Aronow and Middleton (2013)--exhibits more favorable asymptotic properties than existing alternatives,…

广义单调性对平均处理效应的识别能力AI 解读

In the context of a binary outcome, treatment, and instrument, Balke and Pearl (1993, 1997) es- tablish that the monotonicity condition of Imbens and Angrist (1994) has no identifying power beyond instrument exogeneity for average potential outcomes and average treatment effects in the sense that adding it to instrument exogeneity does not decrease the identified sets for those parameters whenever those restrictions are consistent with the distribution of the observable…

受高阶影响函数启发的随机实验协变量调整AI 解读

Higher-Order Influence Functions (HOIF), developed in a series of papers over the past twenty years, are a fundamental theoretical device for constructing rate-optimal causal-effect estimators from observational studies. However, the value of HOIF for analyzing well-conducted randomized controlled trials (RCT) has not been explicitly explored. In the recent U.S. Food and Drug Administration and European Medicines Agency guidelines on the practice of covariate adjustment in…

合成生存控制：面向事件发生时间反事实的合成控制扩展AI 解读

Estimating causal effects on time-to-event outcomes from observational data is particularly challenging due to censoring, limited sample sizes, and non-random treatment assignment. The need for answering such "when-if" questions--how the timing of an event would change under a specified intervention--commonly arises in real-world settings with heterogeneous treatment adoption and confounding. To address these challenges, we propose Synthetic Survival Control (SSC) to…

统一空间混杂处理方法的工具变量框架AI 解读

Studies investigating the causal effects of spatially varying exposures on outcomes often rely on observational and spatially indexed data. A prevalent challenge is unmeasured spatial confounding, where an unobserved spatially varying variable affects both exposure and outcome, leading to biased estimates and invalid confidence intervals. There is a very large literature on spatial statistics that attempts to address unmeasured spatial confounding bias; most of this…

利用机器学习分解不平等并处理共同支撑问题AI 解读

The Kitagawa-Oaxaca-Blinder decomposition splits the difference in means between two groups into an explained part, due to observable factors, and an unexplained part. In this paper, we reformulate this framework using potential outcomes, highlighting the critical role of the reference outcome. To address limitations like common support and model misspecification, we extend Neumark's (1988) weighted reference approach with a doubly robust estimator. Using Neyman…

通过神经对抗不变性学习从异质环境中探寻因果关系AI 解读

Pursuing causality from data is a fundamental problem in scientific discovery, treatment intervention, and transfer learning. This paper introduces a novel algorithmic method for addressing nonparametric invariance and causality learning in regression models across multiple environments, where the joint distribution of response variables and covariates varies, but the conditional expectations of outcome given an unknown set of quasi-causal variables are invariant. The…

结合陈述偏好与显示偏好AI 解读

Can stated preferences inform counterfactual analyses of actual choice? This research proposes a novel approach to researchers who have access to both stated choices in hypothetical scenarios and actual choices, matched or unmatched. The key idea is to use stated choices to identify the distribution of individual unobserved heterogeneity. If this unobserved heterogeneity is the source of endogeneity, the researcher can correct for its influence in a demand function…

多变量样本选择模型中的因果推断与双重机器学习AI 解读

We propose plug-in (PI) and double machine learning (DML) estimators of average treatment effect (ATE), average treatment effect on the treated (ATET) and local average treatment effect (LATE) in the multivariate sample selection model with ordinal selection equations. Our DML estimators are doubly-robust and based on the efficient influence functions. Finite sample properties of the proposed estimators are studied and compared on simulated data. Specifically, the results of…

空间随机化设计如何改进政策评估AI 解读

This article studies the benefits of using spatially randomized experimental designs which partition the experimental area into distinct, non-overlapping units with treatments assigned randomly. Such designs offer improved policy evaluation in online experiments by providing more precise policy value estimators and more effective A/B testing algorithms than traditional global designs, which apply the same treatment across all units simultaneously. We examine both parametric…

高度相关暴露下多变量孟德尔随机化的分组识别与变量选择AI 解读

Multivariable Mendelian Randomization (MVMR) estimates the direct causal effects of multiple risk factors on an outcome using genetic variants as instruments. The growing availability of summary-level genetic data has created opportunities to apply MVMR in high-dimensional settings with many strongly correlated candidate risk factors. However, existing methods face three major limitations: weak instrument bias, limited interpretability, and the absence of valid…

允许因果循环与潜在混杂的贝叶斯因果发现AI 解读

Learning causality from observational data has received increasing interest across various scientific fields. However, most existing methods assume the absence of latent confounders and restrict the underlying causal graph to be acyclic, assumptions that are often violated in many real-world applications. In this paper, we address these challenges by proposing a novel framework for causal discovery that accommodates both cycles and latent confounders. By leveraging the…

阶梯楔形整群随机试验中的预期效应AI 解读

In stepped wedge cluster randomized trials (SW-CRTs), the intervention is rolled out to clusters over multiple periods. A standard approach for analyzing SW-CRTs utilizes the linear mixed model, where the treatment effect is only present after the treatment adoption, under the assumption of no anticipation. This assumption, however, may not always hold in practice because stakeholders, providers, or individuals who are aware of the treatment adoption timing (especially when…

存在溢出与部分资格限制的二部实验：总处理效应估计AI 解读

We study randomized experiments in bipartite systems where only a subset of treatment-side units are eligible for assignment while all units continue to interact, generating interference. We formalize eligibility-constrained bipartite experiments and define estimands aligned with full deployment: the Primary Total Treatment Effect (PTTE) on eligible units and the Secondary Total Treatment Effect (STTE) on ineligible units. Under randomization within the eligible set, we give…

异质性处理效应的变量重要性度量AI 解读

Motivated by applications in precision medicine and treatment effect heterogeneity, recent research has focused on estimating conditional average treatment effects (CATEs) using machine learning (ML). CATE estimates may represent complicated functions that provide little insight into the key drivers of heterogeneity. Therefore, we introduce nonparametric treatment effect variable importance measures (TE-VIMs), based on the mean-squared error (MSE) in predicting the…

存在样本构成变化时的双重差分AI 解读

This paper studies Difference-in-Differences (DiD) setups with repeated cross-sectional data and potential compositional changes across time periods. We begin our analysis by deriving the efficient influence function and the semiparametric efficiency bound for the average treatment effect on the treated (ATT). We introduce nonparametric estimators that attain the semiparametric efficiency bound under mild rate conditions on the estimators of the nuisance functions,…

面向信息物理安全的因果数字孪生：工业控制系统稳健异常检测框架AI 解读

Industrial Control Systems (ICS) in water distribution and treatment face cyber-physical attacks exploiting network and physical vulnerabilities. Current water system anomaly detection methods rely on correlations, yielding high false alarms and poor root cause analysis. We propose a Causal Digital Twin (CDT) framework for water infrastructures, combining causal inference with digital twin modeling. CDT supports association for pattern detection, intervention for system…