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高维线性回归估计：以 Post-Double-Autometrics 替代 Post-Double-LassoAI 解读

Post-Double-Lasso is becoming the most popular method for estimating linear regression models with many covariates when the purpose is to obtain an accurate estimate of a parameter of interest, such as an average treatment effect. However, this method can suffer from substantial omitted variable bias in finite sample. We propose a new method called Post-Double-Autometrics, which is based on Autometrics, and show that this method outperforms Post-Double-Lasso. Its use in a…

基于深度生成学习的条件分布相等性检验框架AI 解读

In this paper, we propose a general framework for testing the conditional distribution equality in a two-sample problem, which is most relevant to covariate shift and causal discovery. Our framework is built on neural network-based generative methods and sample splitting techniques by transforming the conditional testing problem into an unconditional one. We introduce the generative classification accuracy-based conditional distribution equality test (GCA-CDET) to illustrate…

具有优化与统计保证的因果加性模型凸混合整数规划AI 解读

We study the problem of learning a directed acyclic graph from data generated according to an additive, non-linear structural equation model with Gaussian noise. We express each non-linear function through a basis expansion, and derive a maximum likelihood estimator with a group l0-regularization that penalizes the number of edges in the graph. The resulting estimator is formulated through a convex mixed-integer program, enabling the use of branch-and-bound methods to obtain…

通过因果子群发现估计生存结局的可解释异质性处理效应AI 解读

Estimating heterogeneous treatment effect (HTE) for survival outcomes has gained increasing attention, as it captures the variation in treatment efficacy across patients or subgroups in delaying disease progression. However, most existing methods focus on post-hoc subgroup identification rather than simultaneously estimating HTE and selecting relevant subgroups. In this paper, we propose an interpretable HTE estimation framework that integrates three meta-learners that…

多次划分下的训练与检验：分样本估计量的中心极限定理AI 解读

As predictive algorithms grow in popularity, using the same dataset to both train and test a new model has become routine across research, policy, and industry. Sample-splitting attains valid inference on model properties by using separate subsamples to estimate the model and to evaluate it. However, this approach has two drawbacks, since each task uses only part of the data, and different splits can lead to widely different estimates. Averaging across multiple splits, I…

大规模异质性处理效应估计框架及其在 Snap 用户历程中的应用AI 解读

Heterogeneous Treatment Effect (HTE) and Conditional Average Treatment Effect (CATE) models relax the assumption that treatment effects are the same for every user. We present a large scale industrial framework for estimating HTE using experimental data from hundreds of millions of Snapchat users. By combining results across many experiments, the framework uncovers latent user characteristics that were previously unmeasurable and produces stable treatment effect estimates at…

在控制错误发现率下识别分布差异AI 解读

We consider the problem of comparing a reference distribution with several other distributions. Given a sample from both the reference and the comparison groups, we aim to identify the comparison groups whose distributions differ from that of the reference group. Viewing this as a multiple testing problem, we introduce a methodology that provides exact, distribution-free control of the false discovery rate. To do so, we introduce the concept of batch conformal p-values and…

含观测协变量的非参数工具变量回归AI 解读

We study the problem of nonparametric instrumental variable regression with observed covariates, which we refer to as NPIV-O. Compared with standard nonparametric instrumental variable regression (NPIV), the additional observed covariates facilitate causal identification and enables heterogeneous causal effect estimation. However, the presence of observed covariates introduces two challenges for its theoretical analysis. First, it induces a partial identity structure, which…

使用外部工具变量的面板向量自回归：识别、估计与推断AI 解读

This paper proposes an identification inspired from the SVAR-IV literature that uses external instruments to identify PVARs, and discusses associated issues of identification, estimation, and inference. I introduce a form of local average treatment effect - the $μ$-LATE - which arises when a continuous instrument targets a binary treatment. Under standard assumptions of independence, exclusion, and monotonicity, I show that externally instrumented PVARs estimate the $μ$-LATE.…

稳健因果推断的统一非凸框架：应对高斯障碍与优化脆弱性AI 解读

This document proposes a Unified Robust Framework that re-engineers the estimation of the Average Treatment Effect on the Overlap (ATO). It synthesizes gamma-Divergence for outlier robustness, Graduated Non-Convexity (GNC) for global optimization, and a "Gatekeeper" mechanism to address the impossibility of higher-order orthogonality in Gaussian regimes.

能否从事件时间数据中识别处理效应衰减AI 解读

Understanding how the causal effect of a treatment evolves over time, including the potential for waning, is important for informed decisions on treatment discontinuation or repetition. For example, waning vaccine protection influences booster dose recommendations, while cost-effectiveness analyses require accounting for long-term efficacy of treatments. However, there is no consensus on the methodology to assess and account for treatment effect waning. Even in randomized…

因果面板估计量的方差估计AI 解读

There has been a recent surge in research on causal panel data models, leading to many new estimators for average causal effects. However, researchers have paid less attention to quantifying the precision of these estimators. This paper addresses that gap by studying the problem of variance estimation in causal panel settings. We develop a unified framework for comparing the three main variance estimators used in these settings: regression-based, Unit-Placebo, and…

用大语言模型模拟人类行为的挑战：因果推断视角AI 解读

Large Language Models (LLMs) have shown impressive potential to simulate human behavior. We identify a fundamental challenge in using them to simulate experiments: when LLM-simulated subjects are blind to the experimental design (as is standard practice with human subjects), variations in treatment systematically affect unspecified variables that should remain constant, violating the unconfoundedness assumption. Using demand estimation as a context and an actual experiment…

非加性条件参数化因果模型下因果图的可识别性AI 解读

Existing approaches to causal discovery often rely on restrictive modeling assumptions that limit their applicability in real-world settings, particularly when data are heavy-tailed or contain a mixture of discrete and continuous variables. Identifiability of causal graphs has been established under several structural models, including linear non-Gaussian models, post-nonlinear models, and location-scale models. However, these frameworks may not capture the diversity of…

处理效应随时间变化时阶梯楔形试验检验功效的影响因素AI 解读

Stepped wedge cluster randomized trials (SW-CRTs) have historically been analyzed using immediate treatment (IT) models, which assume the effect of the treatment is immediate after treatment initiation and subsequently remains constant over time. However, recent research has shown that this assumption can lead to severely misleading results if treatment effects vary with exposure time, i.e. time since the intervention started. Models that account for time-varying treatment…

网络干扰下因果效应估计中 Horvitz–Thompson 估计量的容许性AI 解读

The Horvitz-Thompson (H-T) estimator is widely used for estimating network causal effects. We study its optimality properties by embedding it in the class of all linear estimators. We show that, under any form of interference, the H-T estimator is inadmissible with respect to mean squared error for designs that generate a random number of units for a given treatment-exposure combination, which includes completely randomized and Bernoulli designs. In contrast, the Hajek and…

为何因果推断的双重稳健估计量在方差估计上并非双重稳健AI 解读

Doubly robust estimators (DRE) are widely used in causal inference because they yield consistent estimators of average causal effect when at least one of the nuisance models, the propensity for treatment (exposure) or the outcome regression, is correct. However, double robustness does not extend to variance estimation; the influence-function (IF)-based variance estimator is consistent only when both nuisance parameters are correct. This raises concerns about applying DRE in…

双重差分框架下监管政策对社会福利影响的评估AI 解读

Quantifying the impact of regulatory policies on social welfare generally requires the identification of counterfactual distributions. Many of these policies (e.g. minimum wages or minimum working time) generate mass points and/or discontinuities in the outcome distribution. Existing approaches in the difference-in-difference literature cannot accommodate these discontinuities while accounting for selection on unobservables and non-stationary outcome distributions. We…

异质性处理效应与因果机制AI 解读

The credibility revolution advances the use of research designs that permit identification and estimation of causal effects. However, understanding which mechanisms produce measured causal effects remains a challenge. The dominant current approach to the quantitative evaluation of mechanisms relies on the detection of heterogeneous treatment effects (HTEs) with respect to pre-treatment covariates. This paper develops a framework to understand when the existence of such…

将右删失事件视作处理的讨论AI 解读

In causal inference literature, potential outcomes are often indexed by the "elimination of all right-censoring events," leading to the perception that such a restriction is necessary for defining well-posed causal estimands. In this paper, we clarify that this restriction is not required: a well-defined estimand can be formulated without indexing on the elimination of such events. Achieving this requires a more precise classification of right-censoring events than has…

用于可解释异质性处理效应估计的因果规则学习新方法AI 解读

Interpretability plays a crucial role in the application of statistical learning to estimate heterogeneous treatment effects (HTE) in complex diseases. In this study, we leverage a rule-based workflow, namely causal rule learning (CRL), to estimate and improve our understanding of HTE for atrial septal defect, addressing an overlooked question in the previous literature: what if an individual simultaneously belongs to multiple groups with different average treatment effects?…

网络因果效应的自回归双重稳健估计AI 解读

This paper develops new methods for causal inference in observational studies on a single large network of interconnected units, addressing two key challenges: long-range dependence among units and the presence of general interference. We introduce a novel network version of Augmented Inverse Propensity Weighted, which combines propensity score and outcome models defined on the network to achieve doubly robust identification and estimation of both direct and spillover causal…

利用效应度量可迁移性的异质性感知联邦因果推断AI 解读

Federated learning of causal estimands offers a powerful strategy to improve estimation efficiency by leveraging data from multiple study sites while preserving privacy. Existing literature has primarily focused on the average treatment effect using single data source, whereas our work addresses a broader class of causal measures across multiple sources. We derive and compare semiparametrically efficient estimators under two transportability assumptions, which impose…

混合对照试验中偏差界定的非参数敏感性分析AI 解读

We study hybrid control trials (HCTs), in which a randomized controlled trial (RCT) is augmented with external control patients. Existing approaches for HCTs typically assume conditional exchangeability of the concurrent and external controls to identify trial-specific effects. When violated, this can induce substantial unquantified bias, which in turn limits the acceptability of HCTs in regulatory settings. We treat violations of mean exchangeability as omitted variable…