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空间混杂：概念、挑战与现有方法综述AI 解读

Spatial confounding is a persistent challenge in spatial statistics, influencing the validity of statistical inference in models that analyze spatially-structured data. The concept has been interpreted in various ways but is broadly defined as bias in estimates arising from unmeasured spatial variation. In this paper we review definitions, classical spatial models, and recent methodological advances, including approaches from spatial statistics and causal inference. We…

BMW：基于胜率比统计量的贝叶斯模型辅助自适应Ⅱ期临床试验设计AI 解读

The win ratio (WR) statistic is increasingly used to evaluate treatment effects based on prioritized composite endpoints, yet existing Bayesian adaptive designs are not directly applicable because the WR is a summary statistic derived from pairwise comparisons and does not correspond to a unique data-generating mechanism. We propose a Bayesian model-assisted adaptive design for randomized phase II clinical trials based on the WR statistic, referred to as the BMW design. The…

genriesz：基于广义 Riesz 回归的自动去偏机器学习 Python 包AI 解读

Efficient estimation of causal and structural parameters can be automated using the Riesz representation theorem and debiased machine learning (DML). We present genriesz, an open-source Python package that implements automatic DML and generalized Riesz regression, a unified framework for estimating Riesz representers by minimizing empirical Bregman divergences. This framework includes covariate balancing, nearest-neighbor matching, calibrated estimation, and density ratio…

事件发生时间结局的超级学习器：实践教程AI 解读

Estimating risks or survival probabilities conditional on individual characteristics based on censored time-to-event data is a commonly faced task. This may be for the purpose of developing a prediction model or may be part of a wider estimation procedure, such as in causal inference. A challenge is that it is impossible to know at the outset which of a set of candidate models will provide the best risk estimates. The super learner is a powerful approach for finding the best…

非结构化数据稳健与有效推断的统一框架AI 解读

To analyze unstructured data (text, images, audio, video), economists typically first extract low-dimensional structured features with a neural network. Neural networks do not make generically unbiased predictions, and biases will propagate to estimators that use their predictions. While structured variables extracted from unstructured data have traditionally been treated as proxies - implicitly accepting arbitrary measurement error - this poses various challenges in an era…

连续纵向中间变量下主层分层的敏感性分析：队列阶梯楔形试验应用AI 解读

Causal inference in the presence of intermediate variables is a challenging problem in many applications. Principal stratification (PS) provides a framework to estimate principal causal effects (PCE) in such settings. However, existing PS methods primarily focus on settings with binary intermediate variables. We propose a novel approach to estimate PCE with continuous intermediate variables in the context of stepped wedge cluster randomized trials (SW-CRTs). Our method…

群组异质性下的变化中的变化与分布合成控制AI 解读

We develop new changes-in-changes (CIC) and distributional synthetic controls (DSC) types of methods when there exists group-level heterogeneity. For CIC, we allow individuals to belong to heterogeneous groups, extending Athey and Imbens (2006) by finding appropriate control groups that share similar group-level unobserved characteristics to the treatment groups. For DSC, we show that the synthetic control units are not necessarily from the same period as in Gunsilius…

基于图机器学习的网络因果效应双重稳健估计AI 解读

We address the challenge of inferring causal effects in social network data. This results in challenges due to interference -- where a unit's outcome is affected by neighbors' treatments -- and network-induced confounding factors. While there is extensive literature focusing on estimating causal effects in social network setups, a majority of them make prior assumptions about the form of network-induced confounding mechanisms. Such strong assumptions are rarely likely to…

基于 Logit 的两阶段最小二乘替代估计量AI 解读

We propose logit-based IV and augmented logit-based IV estimators that serve as alternatives to the traditionally used 2SLS estimator in the model where both the endogenous treatment variable and the corresponding instrument are binary. Our novel estimators are as easy to compute as the 2SLS estimator but have an advantage over the 2SLS estimator in terms of causal interpretability. In particular, in certain cases where the probability limits of both our estimators and the…

条件可分离效应的近端因果推断AI 解读

Scientists regularly pose questions about treatment effects on outcomes conditional on a post-treatment event. However, causal inference in such settings requires care, even in perfectly executed randomized experiments. Recently, the conditional separable effect (CSE) was proposed as an interventionist estimand that corresponds to scientifically meaningful questions in these settings. However, existing results for the CSE require no unmeasured confounding between the outcome…

潜在文本处理的因果效应估计AI 解读

Understanding the causal effects of text on downstream outcomes is a central task in many applications. Estimating such effects requires researchers to run controlled experiments that systematically vary textual features. While large language models (LLMs) hold promise for generating text, producing and evaluating controlled variation requires more careful attention. In this paper, we present an end-to-end pipeline for the generation and causal estimation of latent textual…

利用潜在过程分析同伴效应AI 解读

I study peer effects that arise from irreversible decisions in the absence of a standard social equilibrium. I model a latent sequence of decisions in continuous time and obtain a closed-form expression for the likelihood, which allows to estimate proposed causal estimands. The method avoids linear-in-means regression by modeling the (possibly unobserved) realized direction of causality, whose probability is identified. I provide identification and estimation results under…

记录分配概率的自适应实验：固定期限自归一化推断AI 解读

Adaptive randomized experiments update treatment probabilities as data accrue, but still require an end-of-study interval for the average treatment effect (ATE) at a prespecified horizon. Under adaptive assignment, propensities can keep changing, so the predictable quadratic variation of AIPW/DML score increments may remain random. When no deterministic variance limit exists, Wald statistics normalized by a single long-run variance target can be conditionally miscalibrated…

存在混杂时反事实分布的非参数识别与推断AI 解读

We propose nonparametric identification and semiparametric estimation of joint potential outcome distributions in the presence of confounding. First, in settings with observed confounding, we derive tighter, covariate-informed bounds on the joint distribution by leveraging conditional copulas. To overcome the non-differentiability of bounding min/max operators, we establish the asymptotic properties for both a direct estimator with polynomial margin condition and a smooth…

以区间删失事件时间为变点的多变量纵向与事件时间联合分析AI 解读

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor dysfunction, psychiatric disturbances, and cognitive decline. The onset of HD is marked by severe motor impairment, which may be predicted by prior cognitive decline and, in turn, exacerbate cognitive deficits. Clinical data, however, are often collected at discrete time points, so the timing of disease onset is subject to interval censoring. To address the challenges posed…

存在样本选择的双重差分AI 解读

We consider the identification of average treatment effects on the treated (ATT) in difference-in-differences (DiD) settings in the presence of endogenous sample selection. We first establish that the conventional DiD estimand generally fails to recover causally meaningful treatment effects, even if selection and treatment assignment are independent. We then partially identify the ATT for individuals whose outcomes would be observed post-treatment under either counterfactual…

面板因果模型中未测混杂的识别诊断：两阶段 LM–Wald 方法AI 解读

Panel data are widely used in political science to draw causal inferences. However, these models often rely on the strong and untested assumption of sequential ignorability--that no unmeasured variables influence both the independent and outcome variables across time. Grounded in psychometric literature on latent variable modeling, this paper introduces the Two-Stage LM-Wald (2SLW) approach, a diagnostic tool that extends the Lagrange Multiplier (LM) and Wald tests to detect…

工具变量回归的差分隐私两阶段梯度下降AI 解读

We study instrumental variable regression (IVaR) under differential privacy constraints. Classical IVaR methods (like two-stage least squares regression) rely on solving moment equations that directly use sensitive covariates and instruments, creating significant risks of privacy leakage and posing challenges in designing algorithms that are both statistically efficient and differentially private. We propose a noisy two-stage gradient descent algorithm that ensures $ρ$-zero-c…

平衡已观测与未观测协变量的多处理协变量自适应随机化：渐近性质AI 解读

Applications of CAR for balancing continuous covariates remain comparatively rare, especially in multi-treatment clinical trials, and the theoretical properties of multi-treatment CAR have remained largely elusive for decades. In this paper, we consider a general framework of CAR procedures for multi-treatment clinal trials which can balance general covariate features, such as quadratic and interaction terms which can be discrete, continuous, and mixing. We show that under…

断点回归效应及其外部有效性的联合推断AI 解读

The external validity of regression discontinuity designs is crucial for informing policy but is rarely examined in applied work. To advance empirical practice, we propose a joint inference procedure for the treatment effect and its local external validity, captured by the treatment effect derivative (TED), within a robust bias correction framework. We further introduce a locally linear treatment effects assumption, which extends the scope of the TED and enables…

未测混杂与干扰并存时的空间因果推断AI 解读

This manuscript unites causal inference and spatial statistics, presenting novel insights for causal inference in spatial data analysis, and drawing from tools in spatial statistics to estimate causal effects. We introduce spatial causal graphs to highlight that spatial confounding and interference can be entangled, in that investigating the presence of one can lead to wrongful conclusions in the presence of the other. Moreover, we show that spatial dependence in the…

考试成绩能否改善教师的学生分轨建议？主分层分析AI 解读

Every year, over one million EU students choose a secondary school track based on teacher recommendations, yet little evidence shows this yields optimal assignments. Using Dutch data, we examine whether access to standardized test scores improves recommendation quality. We develop a Principal-Stratification metric in a quasi-randomized setting, conduct a welfare analysis that flexibly weights short- and long-term losses, and assess principal fairness by examining whether…

非比例风险下平均风险率的高效去偏学习AI 解读

The hazard ratio from the Cox proportional hazards model is a ubiquitous summary of treatment effect. However, when hazards are non-proportional, the hazard ratio can lose a stable causal interpretation and become study-dependent because it effectively averages time-varying effects with weights determined by follow-up and censoring. We consider the average hazard (AH) as an alternative causal estimand: a population-level person-time event rate that remains well-defined and…

匹配后的双向固定效应估计AI 解读

When estimating treatment effects with two-way fixed effects (2WFE) models, researchers often use matching as a pre-processing step when the parallel trends assumption is thought to hold conditionally on covariates. Specifically, in a first step, each treated unit is matched to one or more untreated units based on observed time-invariant covariates. In the second step, treatment effects are estimated with a 2WFE regression in the matched sample, reweighting the untreated…