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边际处理效应与异质性处理效应的联合估计AI 解读

Randomized clinical trials typically aim to estimate a marginal treatment effect. While covariate adjustment can improve precision, it may change the estimand in nonlinear models due to noncollapsibility, leading to conditional rather than marginal treatment effects. At the same time, identifying prognostic and predictive covariates is important for understanding treatment effect heterogeneity and informing clinical decision-making. Keeping marginal interpretability while…

通过隐含干预进行因果推断AI 解读

In the context of having an instrumental variable, the standard practice in causal inference begins by targeting an effect of interest and proceeds by formulating assumptions enabling its identification. We turn this around by adhering to the interventions the observational distribution allows to identify, rather than starting with a desired causal estimand and imposing untestable conditions. The randomization of an instrument and its exclusion restriction define a class of…

含未观测因果路径与后门路径的因果加性模型AI 解读

Causal additive models provide a tractable yet expressive framework for causal discovery in the presence of hidden variables. When unobserved backdoor or causal paths exist between two variables, their causal relationship is often unidentifiable under existing theories. We establish sufficient conditions under which causal directions can be identified in many such cases. These conditions rely on new characterizations of regression sets to determine independence among…

动态阈值设计中的非参数因果推断AI 解读

We consider causal inference in dynamic settings where treatment is assigned by thresholding a state variable that can change over time. There is a large literature on regression-discontinuity methods building on the fact that, in the static setting, treatment assignment via threshold crossing induces a quasi-experimental design that enables pragmatic causal inference. But dynamic settings involve challenges not present in the static setting, e.g., past treatments may affect…

利用产品发布数据重新评估因果估计方法AI 解读

Recent developments in causal machine learning methods have made it easier to estimate flexible relationships between confounders, treatments and outcomes, making unconfoundedness assumptions in causal analysis more palatable. How successful are these approaches in recovering ground truth baselines? In this paper we analyze a new data sample including an experimental rollout of a new feature at a large technology company and a simultaneous sample of users who endogenously…

错位实施双重差分中组别—时间—分层效应的贝叶斯估计AI 解读

Difference-in-Differences designs with staggered treatment adoption are widely used to study heterogeneous treatment effects across cohorts and time periods. We develop a probabilistic framework for estimating potentially high-dimensional ATT arrays that vary across cohorts, periods, and strata defined by baseline covariates. The framework jointly estimates subgroup-specific treatment effects through a unified likelihood-based model, stabilizing inference in sparse…

CausalGuard：因果图不确定性下的保形推断AI 解读

Estimating treatment effects from observational data requires choosing an adjustment set, but valid adjustment depends on an unknown causal graph. Graph misspecification can cause under-coverage, while graph-agnostic conformal wrappers may regain nominal coverage only through large padding. We introduce CausalGuard, a structure-weighted conformal framework that calibrates after aggregating graph-conditional doubly robust pseudo-outcomes. Candidate DAGs are proposed from an…

等噪声方差假设下结构 VAR 模型的因果发现AI 解读

Causal discovery from multivariate time series is challenging when causal effects may occur both across time and within the same sampling interval. This issue is especially important in applications such as neuroscience, where the sampling rate may be coarse relative to the underlying dynamics and contemporaneous effects need not form an acyclic graph. We study causal discovery in linear Gaussian structural VAR models under an equal noise variance assumption, meaning that…

增强大语言模型的因果推理：用于精准微调的因果归因模型AI 解读

This paper introduces a causal attribution model to enhance the interpretability of large language models (LLMs) and improve their causal reasoning abilities via precise fine-tuning. Despite LLMs' proficiency in diverse tasks, their reasoning processes often remain black box, and thus restrict targeted enhancement. We propose a novel causal attribution model that utilizes "do-operators" for constructing interventional scenarios, allowing us to quantify the contribution of…

可能非连续结局下处理组的分位数与分布处理效应AI 解读

Applied Difference-in-Differences studies often involve outcomes that are discrete, mixed, censored, or otherwise non-continuously distributed, while policy questions frequently concern distributional effects rather than mean effects alone. This paper develops a distributional DiD framework for identifying and conducting uniform inference on distribution and quantile treatment effects on the treated in such settings under stated identifying and regularity conditions.…

暴露数据缺失的检测阴性设计中疫苗有效性与免疫相关指标的目标最大似然估计AI 解读

The test-negative design (TND) is a resource-efficient observational study design that can assess vaccine effectiveness and exposure-proximal immune correlates of disease. The TND enrolls symptomatic individuals seeking diagnostic testing and compares case status by an exposure variable, such as vaccination status or immune marker level, that is measured at testing. While the TND reduces confounding by healthcare-seeking behavior, other sources of confounding may remain. TND…

少量处理单位情形下的统计推断AI 解读

In many causal inference applications, only one or a few units (or clusters of units) are treated. An important challenge in such settings is that standard inference methods relying on asymptotic theory may be unreliable, even with large total sample sizes. This survey reviews and categorizes inference methods designed to accommodate few treated units, considering cross-sectional and panel data methods. We discuss trade-offs and connections between different approaches. In…

不完备物理模型下异方差随机动力系统的因果发现AI 解读

Causal discovery is a data-driven paradigm for analyzing complex systems, while physics-based models, such as ordinary differential equations (ODEs), provide mechanistic structure for real-world dynamical processes. Integrating these paradigms can improve identifiability, stability, and robustness. However, real dynamical systems often exhibit cyclic interactions and nonstationarity, whereas many causal discovery methods rely on acyclicity, stationarity, or equilibrium…

缺失数据与簇图：簇层面缺失和变量层面缺失AI 解读

Missing data is pervasive in many scientific domains such as public health, environmental science, and the social sciences. Recoverability from missing data is typically studied using fully specified variable-level missingness models despite that, in many applications, only coarse structural information is available, for instance when variables are grouped into clusters due to limited knowledge or interpretability reasons. In this paper, we investigate recoverability from…

疫苗效力衰减的简便高功效检验AI 解读

Determining whether vaccine efficacy wanes is important for individual and public decision making. Yet, quantification of waning is a subtle task. The classical approaches cannot be interpreted as measures of declining efficacy unless we impose unreasonable assumptions. Recently, formal causal estimands designed to quantify vaccine waning have been proposed. These estimands can be bounded under weaker assumptions, but the bounds are often too wide to make claims about the…

利用随机试验评估观测数据的条件平均治疗效应估计AI 解读

Conditional average treatment effects (CATEs) are increasingly estimated from observational data and used to guide policy and individualized treatment decisions. Before such estimates can be trusted in practice, their predictive fitness needs to be assessed, yet observational data alone offer limited opportunities for doing so. We propose CATE Assessment via Fitness Evaluation (CAFE), a formal framework for directly assessing the goodness-of-fit of a CATE estimate learned…

模型误设下观测研究中倾向得分模型与因果估计量的应用AI 解读

Propensity score (PS) methods are widely used in observational studies to reduce confounding and estimate causal treatment effects. However, the validity of PS-based causal estimators depends heavily on correct model specification, and model misspecification may lead to substantial bias and instability. In this study, we systematically evaluate the performance of commonly used causal estimators, including response surface modeling (RSM), inverse probability weighting (IPW),…

考虑未来时的个体反应估计AI 解读

We propose an approach to estimate how individuals' expectations influence their responses to a counterfactual change. The approach relies on average partial effects, which recover counterfactual impacts under conditions that we specify. We propose a three-step estimation method that relies on panel data on subjective expectations. We illustrate our approach in a model of consumption and saving, focusing on the impact of an income tax that not only changes current income but…

条件边际效应估计的实用指南：现代方法AI 解读

This Element offers a practical guide to estimating conditional marginal effects-how treatment effects vary with a moderating variable-using modern statistical methods. Commonly used approaches, such as linear interaction models, often suffer from unclarified estimands, limited overlap, and restrictive functional forms. This guide begins by clearly defining the estimand and presenting the main identification results. It then reviews and improves upon existing solutions, such…

固定匹配数匹配估计量的极限定理AI 解读

This paper re-examines the limit theorems of Abadie and Imbens for nearest-neighbor matching estimators of average treatment effects with a fixed number of matches. We establish, for the first time, a non-normalized central limit theorem (CLT) with an explicitly calculated limiting variance. The key ingredients are to prove the convergence of the normalizing statistic appearing in the CLT of Abadie and Imbens to its mean, and to calculate the closed form of the limit of this…

谐波合成控制方法AI 解读

Synthetic control methods can produce misleading counterfactual predictions when outcome series contain unit-specific stochastic trends, a common feature of nonstationary macroeconomic data. Existing remedies, such as pre-filtering or differencing, reduce spurious matching but may discard shared nonstationary variation that helps estimate donor weights. We propose Harmonic Synthetic Control (HSC), which replaces this binary choice with a soft allocation mechanism. HSC…

利用扩展桥函数识别干预联合分布AI 解读

Existing identification results in proximal causal inference often focus on marginal interventional distributions using standard outcome or treatment bridge functions. These methods do not generally identify joint interventional distributions that contain all proxy variables that were used to define the corresponding bridge functions. In many applications, however, these joint interventional distributions are a natural target of interest. We introduce extended bridge…

单变量与双变量结局的简便分布双重差分估计量AI 解读

We provide a simple distribution regression estimator for treatment effects in the difference-in-differences (DiD) design. Our procedure is particularly useful when the treatment effect differs across the distribution of the outcome variable. Our proposed estimator easily incorporates covariates and, importantly, can be extended to settings where the treatment potentially affects the joint distribution of multiple outcomes. Our key identifying restriction is that the…

集合值政策学习AI 解读

Conventional treatment policies map patient covariates to a single recommended intervention in order to maximize expected clinical outcomes. Although a rich body of causal inference methods has been developed to estimate such policies, point-valued recommendations can be highly sensitive to estimation uncertainty, model specification, and finite-sample variability, while typically providing little guidance about how confident one should be in the recommended action. In this…