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Adversarial Estimation of Binary Configuration Probabilities under Sparse Dependence

稀疏依赖下二元配置概率的对抗估计

We consider the problem of estimating binary configuration probabilities, which is common in operations management applications, including product bundling, advertising, etc. Existing approaches typically model each assortment as a category and apply multinomial models to estimate the choice probabilities; while computationally convenient, these methods do not exploit independence structures in the joint distribution and may therefore be statistically inefficient when the…

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Matched Triple-Differences: A Framework for Covariate Adjustment

匹配三重差分:协变量调整框架

A common empirical strategy in triple-differences (DDD) is to include either covariate trends or covariate levels to a three-way fixed effects (3WFE) regression. This strategy is typically motivated by the conditional parallel gaps assumption which assumes that deviations from parallel trends are similar among units with comparable observed covariates. We formally study both 3WFE specifications and show that, in general, neither consistently estimates the average treatment…

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Bootstrap Inference with a Randomly Assigned Regressor: Covariance Filtering and the Limits of Marginal Resampling

随机分配回归变量的自助法推断:协方差过滤与边际重抽样的局限

Random assignment can make ordinary least squares (OLS) inference insensitive to outcome dependence, yet iid resampling can still fail because assignment and resampling need not remove the same covariance terms. With binary treatment, the iid variance target differs from the sampling variance by exactly minus aggregate cross-unit covariance of treatment effects. Under a Gaussian first-order limit, positive covariance leads to over-rejection and negative covariance to…

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Structural Causal Models for Extremes: an Approach Based on Exponent Measures

We introduce a new formulation of structural causal models for extremes, called the extremal structural causal model (eSCM). Unlike conventional structural causal models, where randomness is governed by a probability distribution, eSCMs use an exponent measure, an infinite-mass law that naturally arises in the analysis of multivariate extremes. Central to this framework are activation variables, which abstract the single-big-jump principle, along with additional…

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Direct estimation and inference of differential Granger causality between two high-dimensional time series

Comparing dependence structures between two related multivariate time series is of fundamental interest in many scientific applications, where changes may occur in both directed temporal interactions and contemporaneous connectivity. Modeling each time series by a vector autoregressive (VAR) model, we propose a new framework for estimation and inference of differential Granger causality (DiffGC) and differential network (DiffNet) structures in high dimensions. The proposed…

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Towards causal effect estimation with learned instrument representations

Instrumental variable (IV) methods mitigate bias from unobserved confounding in observational causal inference but rely on the availability of a valid instrument, which can often be difficult or infeasible to identify in practice. In this paper, we propose a representation learning approach that constructs instrumental representations from observed covariates, which could enable IV-based estimation even in the absence of an explicit instrument. Our model (ZNet) achieves this…

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Network-Constrained Matching and Randomization-Based Inference for Causal Effects

网络约束匹配与因果效应的随机化推断

Matching is widely used to mimic randomized experiments by forming matched sets in which treated and control units differ only randomly with respect to observed covariates. However, when the study population consists of interconnected units from a single network or a small number of networks, matching solely on observed covariates may produce matched units that are more closely connected in the network than would occur by chance. This increased network proximity within…

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Neymanian inference in randomized experiments

随机实验中的 Neyman 式推断

In his seminal 1923 work, Neyman studied the variance estimation problem for the difference-in-means estimator of the average treatment effect in completely randomized experiments. He proposed a variance estimator that is conservative in general and unbiased under homogeneous treatment effects. While widely used under complete randomization, there is no unique or natural way to extend this estimator to more complex designs. To this end, we show that Neyman's estimator can be…

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Co-Supervised Tree Synthesis for Interpretable Subgroup Identification and Honest Treatment Effect Inference in Randomized Trials

共同监督树合成:随机试验中的可解释亚组识别与诚实处理效应推断

Identifying patient subgroups with heterogeneous treatment effects is central to precision medicine, yet existing approaches face a tension. Black-box methods estimate individualized effects well but yield no interpretable subgroups, while tree-based methods produce explicit partitions but are unstable and less accurate in moderate-sample trials. We propose CausalSynthTree, a co-supervised method in which black-box causal estimators guide construction of an interpretable…

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A Path-Dependent Agent-Based Microsimulation of Crime and Violence Reduction Policy Portfolios in Bolivia: Survey Calibration, Adaptive Emulator Ensembles, Global Sensitivity, Tempered MCMC, and Multi-Objective Policy Analysis

玻利维亚犯罪与暴力治理政策组合的路径依赖主体微观模拟

This study develops a survey-calibrated, path-dependent agent-based microsimulation for evaluating crime and violence reduction policies in Bolivia. A synthetic population is constructed from the 2025 Household Survey and the fourth-quarter 2025 Continuous Employment Survey using official expansion weights and cross-survey donor matching. The model combines heterogeneous agents, place-based risk, criminal adaptation, institutional capacity, community organization, and…

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Risk-Calibrated Balancing for High-Dimensional Causal Extrapolation

高维因果外推中的风险校准平衡

In observational causal inference, covariate balancing is widely used to reduce source-target covariate shift, but under weak overlap in high dimensions, stronger balance can induce concentrated weights and increase variance. Balance measures how well the target covariate distribution is represented, but does not by itself determine how reliably the counterfactual mean can be estimated. We develop risk-calibrated balancing for the average treatment effect on the treated,…

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Flexible Nonparametric Inference for Causal Effects under the Front-Door Model

前门模型下因果效应的灵活非参数推断

Evaluating causal treatment effects in observational studies requires addressing confounding. While the back-door criterion enables identification through adjustment for observed covariates, it fails in the presence of unmeasured confounding. The front-door criterion offers an alternative by leveraging variables that fully mediate the treatment effect and are unaffected by unmeasured confounders of the treatment-outcome pair. We develop novel one-step and targeted minimum…

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Pragmatic DML with AI-Learned Representations

使用 AI 学习表征的实用双重机器学习

Text, images, and other rich covariates are increasingly compressed into AI-learned representations and then used as controls in causal analysis. We study when this approach is valid and develop a practical framework for causal inference with learned representations. For a broad class of estimands, an imperfect representation distorts the target causal parameter by the product of two representation errors: one in the outcome regression and one in the balancing weight (or…

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Cross-Fitting Under Nonregularity: Normality and Inference via Locality

非正则情形下的交叉拟合:基于局部性的正态性与推断

Cross-fitting is routine in much of applied research. While conventional confidence intervals that ignore cross-fold dependence are asymptotically valid in several settings, they undercover in many applications that share a common form of nonregularity: from the classic cross-validation problem of testing whether a fitted model outperforms another, to testing for heterogeneous treatment effects with machine learning, to estimating the value of a potentially non-unique…

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Evaluating Threshold Policies in Randomized Threshold Designs: A Cautionary Tale for Regression Discontinuity Designs

随机阈值设计中的政策评估:对回归不连续设计的警示

Many policies assign treatment according to whether a score crosses a cutoff. Regression discontinuity (RD) designs identify the effect of treatment assignment, but the threshold policy itself may also reshape individuals' incentives, inducing behavioral responses that affect outcomes even holding treatment status fixed---a channel that conventional RD designs cannot capture. We develop a framework that exploits randomized variation in policy thresholds, together with…

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Interpretable Discovery from Unstructured Data: A High-Dimensional Approach

We propose an automatic, general-purpose framework for making discoveries from unstructured data (e.g., text data from open-ended surveys of economic beliefs). The framework leverages recent methods from the literature on AI interpretability to transform unstructured datasets into high-dimensional, structured datasets of interpretable concept measurements; specifies concept-level parameters and null hypotheses based on this transformed dataset; tests these hypotheses using…

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Cheap subsampling bootstrap confidence intervals with applications to longitudinal causal inference

The bootstrap is widely used to construct confidence intervals but may perform poorly for some estimators. We consider semiparametric estimators that use cross-validation to estimate nuisance pa- rameters and can be computationally expensive in large datasets. We illustrate potential problems with bootstrapping with replacement when cross-validation is used and extend the cheap bootstrap confidence interval to subsampling without replacement for asymptotically linear…

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A robust regression approach to synthetic control with interference

存在干扰时合成控制的稳健回归方法

Synthetic control methods are widely used for policy evaluation, but most existing approaches rule out interference among units, compromising validity when such effects are present. We develop a framework that accommodates contaminated donor pools and unknown interference patterns through two stages: factor-model adjustment for unobserved confounding, followed by robust regression in which direct and interference effects appear as a sparse outlier component. We study two…

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Statistical Methods for Crossover Trials: A Review of Classical and Recent Developments

交叉试验的统计方法:经典与近期进展综述

A comprehensive review of the literature on crossover design is needed to highlight its evolution, applications, and methodological advancements across various fields. Given its widespread use in clinical trials and other research domains, understanding this design's challenges, assumptions, and innovations is essential for optimizing its implementation and ensuring accurate, unbiased results. This article extensively reviews the history and statistical inference methods for…

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Projection-based significance test for longitudinally collected functional data under a crossover design

Wearable devices for continuous electronic health monitoring often capture data at frequent intervals under a dense functional design. The focal point is the analysis of longitudinal functional data, wherein functional trajectories are observed repeatedly over time. This work is motivated by the interest in assessing the efficacy of a noninflammatory medication, meloxicam, on the daily activity levels of household cats with a pre-existing condition of osteoarthritis under a…

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Externally Valid Selection of Experimental Sites via the k-Median Problem

We present a decision-theoretic justification for viewing the question of how to best choose where to experiment in order to optimize external validity as a $k$-median problem, a popular problem in computer science and operations research. In particular, when treatment effect heterogeneity across experimental and policy-relevant sites is substantial (in a sense we make precise), we present conditions under which minimizing the worst-case, welfare-based regret among all…

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Quantifying and Correcting Measurement Error in LLM-Generated Classifications: A Beta-Binomial Latent Class Model for Correlated Repeated Judgments

Large language models are increasingly used to classify text at scale. Because their outputs are stochastic, it is common to query a model several times per item and aggregate the results, and latent class models offer a principled way to convert such repeated ratings into estimates of outcome prevalence and of the model's error rates. These models assume that repeated ratings of the same item are conditionally independent given the true label. We examine this assumption…

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Notes on Forré's Notion of Conditional Independence and Causal Calculus for Continuous Variables

关于 Forré 条件独立概念与连续变量因果演算的札记

Recently, Forré (arXiv:2104.11547, 2021) introduced transitional conditional independence, a notion of conditional independence that provides a unified framework for both random and non-stochastic variables. The original paper establishes a strong global Markov property connecting transitional conditional independencies with suitable graphical separation criteria for directed mixed graphs with input nodes (iDMGs), together with a version of causal calculus for iDMGs in a…

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Mining Causality: AI-Assisted Search for Instrumental Variables

挖掘因果关系:人工智能辅助搜索工具变量

The instrumental variables (IVs) method is a leading empirical strategy for causal inference. Finding IVs is a heuristic and creative process, and justifying their validity---especially exclusion restrictions---is largely rhetorical. We propose using large language models (LLMs) to search for new IVs through narratives and counterfactual reasoning, similar to how a human researcher would. The stark difference, however, is that LLMs can dramatically accelerate this process…

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