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最优连续处理效应的识别与估计AI 解读

Estimating continuous treatment effects is hard because average-derivative estimators rely on an ill-posed conditional-density score. Recent work makes a bounded outcome weight the primitive, characterizing a class of weighted average derivative effects without density estimation. In this paper, we develop the identification and estimation theory for the optimally efficient estimands of this class under homoskedasticity and heteroskedasticity. On identification, we show that…

基于方差的治疗效应异质性检验AI 解读

This paper proposes a robust nonparametric hypothesis test for the existence of heterogeneous treatment effects. We focus on the variance of the Conditional Average Treatment Effect (CATE) as a natural omnibus parameter, where a non-zero variance implies the presence of relevant heterogeneity. Standard inference for this parameter faces a fundamental theoretical challenge. On one hand, evaluating variance components on the same sample leads to null degeneracy, where the…

因果异质性的分辨率AI 解读

Causal subgroup analyses often report a small number of groups summarizing treatment effect heterogeneity, as if that number were a well-defined estimand. Outside genuinely latent class populations, however, a ``true'' subgroup count is model dependent rather than a population functional. We replace it with a new population estimand, the resolution profile, a functional of the causal feature law giving the fewest groups explaining a prescribed fraction of causal…

不膨胀协变量不平衡方差的临床试验自适应随机化AI 解读

Covariate adaptive randomization (CAR) procedures are extensively used to reduce the likelihood of covariate imbalances occurring in clinical trials. In literatures, a lot of CAR procedures have been proposed so that the specified covariates are balanced well between treatments. However, the variance of the imbalance of the unspecified covariates may be inflated comparing to the one under the simple randomization. The inflation of the variance causes the usual test of…

扩散引导平滑的几何自适应反事实分布学习AI 解读

We study counterfactual distribution learning for high-dimensional outcomes whose laws may concentrate near lower-dimensional structure. Standard isotropic smoothing ignores this geometry, leading to unfavorable scaling and unstable local inference. We propose semiparametrically debiased, diffusion-guided estimators for smoothed counterfactual densities and their scores. These estimators combine causal nuisance adjustment with geometry-adaptive localization driven by a…

用于个体化治疗规则的结局加权学习神经网络AI 解读

Individualized treatment rules (ITRs) formalize precision medicine by assigning treatments according to patient covariates, with the goal of maximizing expected clinical outcomes. Such rules are especially important when treatment effects vary across patients, as in chronic diseases where demographic, clinical, genetic, imaging, or biomarker information may modify the relative benefits of available therapies. Individualized treatment rules (ITRs) formalize precision medicine…

简约、灵活、忠实：通过 Frengression 模拟因果数据AI 解读

Machine learning has revitalized causal inference by combining flexible models and principled estimators, yet robust benchmarking and evaluation remain challenging with real-world data. In this work, we introduce frengression, a deep generative realization of the frugal parameterization that models the joint distribution of covariates, treatments and outcomes around the causal margin of interest. Frengression provides accurate estimation and flexible, faithful simulation of…

种族的哪一种效应？不固定其他特征的因果推断AI 解读

Empirical studies of racial discrimination vary race while holding nonracial traits fixed, a design the literature defends as what credible inference requires. This defense bundles two claims: which effect of race a study should target, and whether its design can recover that effect. I separate them. The same randomization that secures credible estimation and inference recovers a family of race estimands, from the all-else-equal effect to a within-race effect that lets…

B-CALM：协变量不匹配下以随机试验为锚的偏差受限贝叶斯信息借用AI 解读

Randomized controlled trials (RCTs) identify treatment effects in the randomized trial population but are often too small for reliable heterogeneity estimation; observational studies (OS) are larger but confounded and measured on only partially overlapping covariates. We develop Bayesian Calibrated ALignment under covariate Mismatch (B-CALM), a Bayesian borrowing method for RCT-defined conditional average treatment effect (CATE) estimation. B-CALM maps source-specific…

刻画信号传递：因果推断与时空几何的联系AI 解读

Causality is pivotal to our understanding of the world, presenting itself in different forms: information-theoretic and relativistic, the former linked to the flow of information, the latter to the structure of space-time. Leveraging a framework introduced in PRA, 106, 032204 (2022), which formally connects these two notions in general physical theories, we study their interplay. Here, information-theoretic causality is defined through a causal modelling approach. First, we…

让事件研究图支持诚实推断：因果分析的函数型数据方法AI 解读

Event study plots are the centerpiece of Difference-in-Differences (DiD) analysis, but current plotting methods cannot provide honest causal inference when the parallel trends and/or no-anticipation assumptions fail. We introduce a novel functional data approach to DiD that directly enables honest causal inference via event study plots. Our DiD estimator converges to a Gaussian process in the Banach space of continuous functions, enabling powerful simultaneous confidence…

单调处理响应下，处理效应超过给定阈值的概率AI 解读

Experiments may, by design, prevent one from observing on a single subject both the response to a treatment and to its absence. Because of this, marginal distributions for both cases may be observable but not their joint distribution, thus obscuring the distribution of the treatment effect. We examine the case where we impose that the treatment effect is nonnegative, also called monotone treatment response, a common assumption relevant to many practical applications. We…

利用处理后变量研究预测性处理效应异质性的经验分层AI 解读

Post-treatment variables (PVs), such as intercurrent events, treatment noncompliance, and behavioral responses to treatment, provide information about individuals' post-treatment responses and may help characterize heterogeneity in treatment effects on the primary outcome. This paper develops an empirical stratification framework to study the treatment effect heterogeneity across baseline-predicted PV response profiles. Specifically, we construct empirical scores from…

处理状态缺失时，如何学习应该干预谁AI 解读

Policy learning methods are increasingly used to inform treatment allocation under budget constraints. Most proposed methods assume complete treatment data, yet applications frequently suffer from missingness that can bias estimates and lead to suboptimal policies. We address this gap by extending efficient estimators for average treatment effect (ATE) estimation to policy value and conditional average treatment effect (CATE) estimation under missing at random (MAR) and…

用于因果推断的生成式合成数据：陷阱、补救与机会AI 解读

Synthetic tabular data are often evaluated by distributional similarity, privacy distance, or train-on-synthetic-test-on-real predictive performance, but these criteria do not ensure validity for causal inference. We show that fully generative tabular synthesizers, including GAN- and LLM-based models, can preserve predictive utility while distorting average treatment effect (ATE) estimates. The failure is structural: ATE preservation requires both a realistic covariate law…

部分可观测的结构因果模型AI 解读

Here we introduce Partially Observed Structural Causal Models (POSCMs) as an extension of structural causal models (SCMs) to settings where upstream contexts co-determine both the interaction structure and downstream mechanisms on observed variables. POSCMs thus provide a self-contained causal modeling framework for endogenous graphs, allowing for an intervention hierarchy spanning node- and edge-level contexts and endogenous variable interventions. To define edge…

干预分布公式的验证AI 解读

We formalize verification in causal graphical models: deciding whether a given observational formula identifies a target interventional distribution. This opens a problem complementary to identification, asking not whether any identifying formula exists, but whether the given formula is identifying. We show that even sound and complete solutions to identification do not solve verification. We propose a falsifier as a first practical route forward, prove that it induces an…

多商品多期库存控制的实验设计AI 解读

Randomized experiments, or A/B testing, are the gold standard for evaluating interventions, yet they remain underutilized in inventory management. This study addresses this gap by analyzing A/B testing strategies in multi-item, multi-period inventory systems with lost sales and capacity constraints. We examine two canonical experimental designs--switchback experiments and item-level randomization--and show that both suffer from systematic bias due to interference: temporal…

智能体经济建模AI 解读

We introduce Agentic Economic Modeling (AEM), a framework that aligns synthetic LLM choices with small-sample human evidence for econometric inference. AEM first generates task-conditioned synthetic choices via LLMs, then learns a bias-correction mapping from task features and raw LLM choices to human-aligned choices, upon which standard econometric estimators perform inference to recover demand elasticities and treatment effects. We validate AEM in two experiments. In a…

聚类处理分配下的遗漏变量偏差敏感性分析AI 解读

Cinelli and Hazlett (2020) develops a sensitivity analysis method for the linear regression model that parameterizes omitted variable bias in terms of two partial $R^2$ parameters capturing the residual variation explained by an omitted confounder in the treatment and outcome respectively. This method is often applied to regressions fit to unit-level data when treatment is assigned at a higher level of aggregation -- as in clustered observational designs. This paper shows…

连续处理随机政策变动下的双重差分AI 解读

Treatment effects of stochastic policy shifts quantify differences in outcomes across counterfactual scenarios with varying treatment distributions. Stochastic policy shifts may be of interest in settings where it is unrealistic or infeasible to deterministically manipulate treatments. In this paper, methods are developed to draw inference about stochastic policy effects under difference-in-differences (DiD) designs with a continuous treatment. The proposed causal estimand…

显著性优先分裂：协调处理效应异质性检测与诚实估计AI 解读

Estimating heterogeneous treatment effects (CATE) requires simultaneously detecting effect modification and quantifying estimation uncertainty. Existing tree-based methods make an uneasy trade-off: significance-based approaches (Radcliffe and Surry 2011) identify subgroup interactions directly but lack valid inference; honest causal trees (Athey and Imbens 2016) deliver nominal confidence interval coverage but use outcome-agnostic splitting criteria that sacrifice…

部分干扰下的高阶溢出效应AI 解读

Interference, under which a unit's outcome is affected by the treatment of other units through network connections, is often present when units interact on a network. When the network of interactions is measured, researchers are often interested in the spillover effect from first-order neighbors. When this is the case, the prevailing approach often involves the neighborhood interference assumption, which is oftentimes overly restrictive. In this paper, we instead rely on a…

MixCIT：面向混合类型数据的核局部多项式去偏条件独立检验AI 解读

Conditional independence testing (CIT) is fundamental to modern statistical inference in areas related to causal discovery and variable selection. While marginal independence is relatively well-understood, despite multiple advances, no existing non-parametric CIT provides a unified, efficient, and statistically guaranteed solution across heterogeneous data. We introduce a graph-based test statistic comparing kernel similarities of the response within composite neighborhoods…