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空间场景下设计型推断中的结果建模AI 解读

In the face of spatial interference, researchers are often interested in estimating treatment effects at specific points located in space. Wang et al. (2025) and Pollmann (2023) provide design-based frameworks for estimating spillover effects on points located across a range of distances from interventions. Although these frameworks are design-based, we show their proposed estimands rely on outcomes that are directly unobservable and therefore, require outcome modeling. When…

GFCM：面向因果发现的尾部敏感混合类型条件独立检验AI 解读

Constraint-based causal discovery like PC and FCI depends on its conditional independence test. Partial correlation and the Generalised Covariance Measure (GCM) detect only the conditional covariance of residuals, so they miss dependence in the mean's nonlinear part, the scale, and the tails. Tests that detect more are biased inside PC, not scalable, only continuous, or not aimed at the tails. Our Generalised Feature Covariance Measure (GFCM) is valid, sensitive beyond…

随机潜在选择与潜在结果AI 解读

Applied econometricians typically model each individual as having fixed outcomes under treatment and control and, in instrumental-variables (IV) settings, fixed treatment decisions under each value of the instrument. This paper asks what changes when outcomes and treatment allocations or choices are stochastic at the individual level. In the model, each individual has a stable (but possibly stochastic) response type consisting of two objects: a treatment choice probability…

多中心随机试验中的稳健协变量调整AI 解读

Augmented inverse probability weighting and G-computation with canonical generalized linear models have become increasingly popular for estimating the average treatment effect (ATE) in randomized experiments. These methods leverage outcome prediction models to adjust for imbalances in baseline covariates across treatment arms, improving power compared to unadjusted analyses, while controlling Type I error, even when models are misspecified. In multi-center trials they are…

随机实验的锐极小极大理论AI 解读

We study minimax-optimal designs and estimators for estimating the sample average treatment effect in finite population randomized experiments, where both design and estimator are unrestricted. For binary potential outcomes, we show this minimax risk is equivalent to the minimax risk $ρ_n^*$ of an estimation problem with $2$ unknown parameters. We leverage this reduction to establish a second-order risk expansion $ρ_n^* = n^{-1} - Cn^{-4/3} + o_n(n^{-4/3})$ for an explicit…

未知干扰下利用面板数据学习处理效应AI 解读

When comparison units may also respond to treatment, panel comparisons reflect both the treatment effect and spillovers. If the interference pattern is unknown, observed outcomes alone do not separate the two. I characterize what can nevertheless be learned from panel outcomes under general restrictions, without requiring an exposure mapping or prior classification of affected donors. The framework scales validity bounds for every convex donor weight by its fit before…

广义贝叶斯政策学习AI 解读

This study proposes a General Bayes framework for policy learning. We consider decision problems in which a decision-maker chooses an action from a given set to maximize expected welfare. Typical examples include treatment choice and portfolio optimization. In such problems, the statistical target is a decision rule, and predicting each potential outcome is not necessarily of primary interest. We formulate this policy-learning problem through loss-based Bayesian updating.…

基于图神经网络的网络数据因果中介分析AI 解读

Causal mediation analysis is typically formulated under no interference, an assumption often violated in networked populations. We develop a nonparametric framework for a single large observed network that allows simultaneous treatment and mediator spillovers and high-dimensional network confounding. Exposure and mediator mappings define causal estimands without restricting the true interference mechanism, separating own from spillover effects without prespecified…

遗漏协变量导致非比例风险时目标风险比的模拟恢复AI 解读

When an omitted covariate whose inclusion would balance proportional hazards is excluded from a proportional hazards model, bias in the estimated treatment effect may arise. The omitted covariate may represent an unobservable biomarker status, an overlooked stratification factor, or a strong continuous prognostic factor. In this paper, we propose a simple simulation-based approach for recovering the target hazard ratio for treatment effect, defined as the hazard ratio from…

部分识别下处理选择的局部渐近理论AI 解读

We provide a new asymptotic framework to derive approximately optimal treatment assignments when sampling noise from data is compounded by fundamental uncertainty due to partial identification. We recenter the reduced-form parameter around its \emph{least-favorable} configuration and consider drifting parameter sequences that yield both diminishing levels of sampling uncertainty and of partial identification. We characterize the limiting decision problem as a normal location…

群变换污染下结构化结果的因果推断：可观测商空间、无损约化与精确随机化检验AI 解读

Structured potential outcomes such as microscopy images may be recorded after an unknown, unit-specific transformation. If that transformation can depend on treatment, covariates or the intrinsic outcome, raw-coordinate analyses may mix biological effects with acquisition geometry. We study the unrestricted observation model X = Γ . Y(A) and characterize its observable information: a target is uniformly recoverable exactly when it is constant on group orbits, while a Borel…

线性结构方程模型半 trek 估计量的半参数推断AI 解读

Linear structural equation models on directed mixed graphs encode causal relationships among variables subject to latent confounding. The half-trek criterion (HTC) provides a graphical sufficient condition for the structural coefficients to be rationally identifiable from the observable covariance matrix, and yields a corresponding closed-form rational estimator. Despite this, the asymptotic distribution of the HTC estimator, and hence valid standard errors and confidence…

整群随机试验中胜负统计量的样本量设计AI 解读

Composite endpoints are increasingly used in clinical trials to capture treatment effects across multiple or hierarchically ordered outcomes. Although inference procedures based on win statistics, such as the win ratio, win odds, and win difference (net benefit) have gained traction in individually randomized trials, their methodological development for cluster-randomized trials remains limited. In particular, there is no formal framework for power and sample size…

竞争风险生存结局的亚组平均处理效应双重稳健目标估计AI 解读

In recent years, precision treatment strategies have gained significant attention in medical research, particularly for patient care. We propose a novel framework for estimating subgroup average treatment effects (ATE) in time-to-event data with competing risks, using ICU patients with sepsis as an illustrative example. Our approach, based on cumulative incidence functions and targeted maximum likelihood estimation (TMLE), achieves both asymptotic efficiency and double…

随机拥堵下的实验设计与估计AI 解读

We study randomized experiments in a service system when stochastic congestion can arise from temporarily limited supply or excess demand. Such congestion gives rise to cross-unit interference between the waiting customers, and analytic strategies that do not account for this interference may be biased. In current practice, one of the most widely used ways to address stochastic congestion is to use switchback experiments that alternatively turn a target intervention on and…

含交互效应的超高维因果中介分析去偏估计AI 解读

Mediation analysis is a crucial tool for uncovering the mechanisms through which a treatment affects an outcome, providing deeper causal insights and guiding effective interventions. Despite substantial advances in mediation analysis with fixed- or low-dimensional mediators and covariates, estimation and inference for mediation functionals remain limited when both mediators and covariates are ultra-high-dimensional. In this paper, we propose an estimator for the mediation…

甜甜圈断点回归设计AI 解读

Donut regression discontinuity (RD) designs exclude observations in a neighborhood around the cutoff. They are widely used in empirical work to address concerns about manipulation, sorting, or measurement error in the running variable. Despite their popularity, donut RD estimators are typically implemented heuristically, with limited formal guidance and unclear implications for bias, variance, and statistical inference. This paper provides a theoretical analysis of donut RD…

使用非同期对照的平台试验因果生存分析AI 解读

Platform trials allow treatment arms to enter and exit over time while maintaining a shared control arm, yielding concurrent and non-concurrent controls (NCC). Pooling NCC is often motivated as a strategy to improve statistical efficiency, but it is unclear which estimand is targeted, what assumptions justify identification and estimation, and when precision gains are achievable; these questions are further complicated by time-to-event/survival data. Motivated by the…

基于半参数累积概率模型的双重稳健分位数处理效应估计AI 解读

The causal inference literature has traditionally focused on estimating the mean of the potential outcome, whereas evaluating how a treatment affects the entire outcome distribution can provide additional information in biomedical research. Quantile treatment effect (QTE) captures such distributional differences, particularly when outcomes are skewed. However, existing approaches for estimating QTE make distributional assumptions about the outcome and are thus sensitive to…

梯度提升混合模型：灵活估计聚类数据的均值与方差成分AI 解读

We introduce a novel way to combine gradient boosting with mixed effects models, whereby the mean and variance components are learned jointly as functions of covariates via likelihood-based gradients. Gradient Boosted Mixed Models (GBMixed) estimates a nonparametric fixed effects function characterizing the overall mean of the response, while also allowing the random effects covariance matrix along with the residual variance to depend on covariates in a flexible manner. We…

结合专家与大语言模型的 g-computation：估计医院干预节省的时间AI 解读

Hospital quality improvement (QI) programs routinely face multiple candidate interventions to optimize hospital flow, but existing methods struggle to estimate and rank the causal effects of such interventions. This work focuses on one of the most standard hospital metrics, the average length of stay (LOS), and its causal estimand, the average time saved. To characterize this causal effect, qualitative approaches rely on expert judgment to map patient trajectories, making…

群体互动实验的统计推断AI 解读

A common experimental research design is one in which individuals are randomly allocated into groups that then interact under different group-level treatment conditions. We develop design-based inference for such "group interaction" experiments, covering scenarios in which groups are either fixed or randomly formed and in which potential outcomes are either fixed relative to others' group assignments or subject to interference. For each scenario, we characterize the causal…

COMPACT：基于完整且不可约因果准则的谱调整得分AI 解读

Observational datasets frequently contain many baseline variables, yet investigators estimating causal effects may not know which variables to include in the adjustment set. Confounding information may also be distributed weakly across many variables. Propensity scores can simplify adjustment by reducing high-dimensional covariates to a scalar with binary treatment. Although the propensity score is the coarsest balancing score, this distributional optimality does not imply…

参数符号一致性的检验AI 解读

This article considers the problem of testing sign agreement among a finite number of parameters. This problem arises in empirical settings such as detecting treatment effects with opposite signs across subgroups, outcomes, or time periods, and testing instrument validity for local average treatment effects. For the null hypothesis that the parameters are either all non-negative or all non-positive, I propose two novel tests: a least favorable test and a conditional test.…