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非随机缺失重复测量数据的替代分析方法AI 解读

We consider studies where multiple measures on an outcome variable are collected over time, but some subjects drop out before the end of follow up. Analyses of such data often proceed under either a 'last observation carried forward' or 'missing at random' assumption. We consider two alternative strategies for identification; the first is closely related to the difference-in-differences methodology in the causal inference literature. The second enables correction for…

含内生解释变量的非可分二元响应模型中的部分识别AI 解读

This paper considers (partial) identification of a variety of counterfactual parameters in binary response models with possibly endogenous regressors. Our framework allows for nonseparable index functions with multi-dimensional latent variables, and does not require parametric distributional assumptions. We leverage results on hyperplane arrangements and cell enumeration from the literature on computational geometry in order to provide a tractable means of computing the…

未测混杂因果推断的双重有效与双重尖锐敏感性分析AI 解读

We consider the problem of constructing bounds on the average treatment effect (ATE) when unmeasured confounders exist but have bounded influence. Specifically, we assume that omitted confounders could not change the odds of treatment for any unit by more than a fixed factor. We derive the sharp partial identification bounds implied by this assumption by leveraging distributionally robust optimization, and we propose estimators of these bounds with several novel robustness…

极端事件因果推断的热带几何AI 解读

Extreme value statistics is the max analogue of classical statistics, while tropical geometry is the max analogue of classical geometry. In this paper, we review recent work where insights from tropical geometry were used to develop new, efficient learning algorithms with leading performance on benchmark datasets in extreme value statistics. We give intuition, backed by performances on benchmark datasets, for why and when causal inference for extremes should be employed over…

将随机试验推断推广至目标总体的全局敏感性分析AI 解读

When individuals participating in a randomized trial differ with respect to the distribution of effect modifiers compared compared with the target population where the trial results will be used, treatment effect estimates from the trial may not directly apply to target population. Methods for extending -- generalizing or transporting -- causal inferences from the trial to the target population rely on conditional exchangeability assumptions between randomized and…

异质性处理效应双重稳健估计量的改进推断AI 解读

We propose a doubly robust approach to characterizing treatment effect heterogeneity in observational studies. We develop a frequentist inferential procedure that utilizes posterior distributions for both the propensity score and outcome regression models to provide valid inference on the conditional average treatment effect even when high-dimensional or nonparametric models are used. We show that our approach leads to conservative inference in finite samples or under model…

处理效应风险：界限与推断AI 解读

Since the average treatment effect (ATE) measures the change in social welfare, even if positive, there is a risk of negative effect on, say, some 10% of the population. Assessing such risk is difficult, however, because any one individual treatment effect (ITE) is never observed, so the 10% worst-affected cannot be identified, while distributional treatment effects only compare the first deciles within each treatment group, which does not correspond to any…

模糊断点回归中的非线性与非可分结构函数AI 解读

Many empirical examples of regression discontinuity (RD) designs concern a continuous treatment variable, but the theoretical aspects of such models are less studied. This study examines the identification and estimation of the structural function in fuzzy RD designs with a continuous treatment variable. The structural function fully describes the causal impact of the treatment on the outcome. We show that the nonlinear and nonseparable structural function can be…

多尺度因果结构学习AI 解读

The inference of causal structures from observed data plays a key role in unveiling the underlying dynamics of the system. This paper exposes a novel method, named Multiscale-Causal Structure Learning (MS-CASTLE), to estimate the structure of linear causal relationships occurring at different time scales. Differently from existing approaches, MS-CASTLE takes explicitly into account instantaneous and lagged inter-relations between multiple time series, represented at…

假想治疗加速：利用观察数据估计肾移植的因果效应AI 解读

Patients with end-stage kidney disease can expect to wait for several years before they receive a transplant, all the while their health deteriorates. How would the survival change if we managed to reduce these waiting times? To provide an answer, we present a continuous-time marginal structural model (MSM) of hypothetical scenarios in which the time until treatment is changed. In these scenarios, the treatment process is defined on a hypothetical time scale where time…

随机网络上的因果推断方法AI 解读

Claiming causal inferences in network settings necessitates careful consideration of the often complex dependency between outcomes for actors. Of particular importance are treatment spillover or outcome interference effects. We consider causal inference when the actors are connected via an underlying network structure. Our key contribution is a model for causality when the underlying network is unobserved and the actor covariates evolve stochastically over time. We develop a…

网络元分析中治疗排序的非参数贝叶斯方法：抗抑郁药比较AI 解读

Network meta-analysis is a powerful tool to synthesize evidence from independent studies and compare multiple treatments simultaneously. A critical task of performing a network meta-analysis is to offer ranks of all available treatment options for a specific disease outcome. Frequently, the estimated treatment rankings are accompanied by a large amount of uncertainty, suffer from multiplicity issues, and rarely permit ties. These issues make interpreting rankings problematic…

两阶段双重差分AI 解读

A recent literature has shown that when adoption of a treatment is staggered and average treatment effects vary across groups and over time, difference-in-differences regression does not identify an easily interpretable measure of the typical effect of the treatment. In this paper, I extend this literature in two ways. First, I provide some simple underlying intuition for why difference-in-differences regression does not identify a group$\times$period average treatment…

个体处理效应的共形敏感性分析AI 解读

Estimating an individual treatment effect (ITE) is essential to personalized decision making. However, existing methods for estimating the ITE often rely on unconfoundedness, an assumption that is fundamentally untestable with observed data. To assess the robustness of individual-level causal conclusion with unconfoundedness, this paper proposes a method for sensitivity analysis of the ITE, a way to estimate a range of the ITE under unobserved confounding. The method we…

结合内部与外部对照对临床试验处理效应进行双重检验AI 解读

Leveraging external controls -- relevant individual patient data under control from external trials or real-world data -- has the potential to reduce the cost of randomized controlled trials (RCTs) while increasing the proportion of trial patients given access to novel treatments. However, due to lack of randomization, RCT patients and external controls may differ with respect to covariates that may or may not have been measured. Hence, after controlling for measured…

用贝叶斯实验设计高效检验情境化因果决策AI 解读

The real-world testing of decisions made using causal machine learning models is an essential prerequisite for their successful application. We focus on evaluating and improving contextual treatment assignment decisions: these are personalised treatments applied to e.g. customers, each with their own contextual information, with the aim of maximising a reward. In this paper we introduce a model-agnostic framework for gathering data to evaluate and improve contextual decision…

正值性：可识别性与可估计性AI 解读

Positivity, the assumption that every unique combination of confounding variables that occurs in a population has a non-zero probability of an action, can be further delineated as deterministic positivity and stochastic positivity. Here, we revisit this distinction, examine its relation to nonparametric identifiability and estimability, and discuss how to address violations of positivity assumptions. Finally, we relate positivity to recent interest in machine learning, as…

连续处理因果效应估计的端到端平衡方法AI 解读

We study the problem of observational causal inference with continuous treatments in the framework of inverse propensity-score weighting. To obtain stable weights, we design a new algorithm based on entropy balancing that learns weights to directly maximize causal inference accuracy using end-to-end optimization. In the process of optimization, these weights are automatically tuned to the specific dataset and causal inference algorithm being used. We provide a theoretical…

无需无混杂假设的福利增益识别与推断AI 解读

This paper studies identification and inference of the welfare gain that results from switching from one policy (such as the status quo policy) to another policy. The welfare gain is not point identified in general when data are obtained from an observational study or a randomized experiment with imperfect compliance. I characterize the sharp identified region of the welfare gain and obtain bounds under various assumptions on the unobservables with and without instrumental…

不变性祖先搜索AI 解读

Recently, methods have been proposed that exploit the invariance of prediction models with respect to changing environments to infer subsets of the causal parents of a response variable. If the environments influence only few of the underlying mechanisms, the subset identified by invariant causal prediction (ICP), for example, may be small, or even empty. We introduce the concept of minimal invariance and propose invariant ancestry search (IAS). In its population version,…

线性回归用于因果推断时的隐含权重AI 解读

A basic principle in the design of observational studies is to approximate the randomized experiment that would have been conducted under controlled circumstances. Now, linear regression models are commonly used to analyze observational data and estimate causal effects. How do linear regression adjustments in observational studies emulate key features of randomized experiments, such as covariate balance, self-weighted sampling, and study representativeness? In this paper, we…

使用筛方法半参数估计平均处理效应AI 解读

Correctly identifying treatment effects in observational studies is very difficult due to the fact that the outcome model or the treatment assignment model must be correctly specified. Taking advantages of semiparametric models in this article, we use single-index models to establish the outcome model and the treatment assignment model, which can allow the link function to be unbounded and have unbounded support. The link function is regarded as a point in an infinitely…

用于因果推断推广与个体化的协变量画像匹配AI 解读

We introduce profile matching, a multivariate matching method for randomized experiments and observational studies that finds the largest possible unweighted samples across multiple treatment groups that are balanced relative to a covariate profile. This covariate profile can represent a specific population or a target individual, facilitating the generalization and personalization of causal inferences. For generalization, because the profile often amounts to summary…

潜在因子诱导的节点簇之间的因果结构发现AI 解读

We consider the problem of learning the structure of a causal directed acyclic graph (DAG) model in the presence of latent variables. We define latent factor causal models (LFCMs) as a restriction on causal DAG models with latent variables, which are composed of clusters of observed variables that share the same latent parent and connections between these clusters given by edges pointing from the observed variables to latent variables. LFCMs are motivated by gene regulatory…