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说服效应的识别AI 解读

This paper examines a commonly used measure of persuasion whose precise interpretation has been obscure in the literature. By using the potential outcome framework, we define the causal persuasion rate by a proper conditional probability of taking the action of interest with a persuasive message conditional on not taking the action without the message. We then formally study identification under empirically relevant data scenarios and show that the commonly adopted measure…

观察性研究中非精确匹配的统计作用AI 解读

In observational causal inference, exact covariate matching plays two statistical roles: (i) it effectively controls for bias due to measured confounding; (ii) it justifies assumption-free inference based on randomization tests. This paper shows that inexact covariate matching does not always play these same roles. We find that inexact matching often leaves behind statistically meaningful bias and that this bias renders standard randomization tests asymptotically invalid. We…

非对称依赖关系的度量与检验AI 解读

Measuring the (causal) direction and strength of dependence between two variables (events), Xi and Xj , is fundamental for all science. Our survey of decades-long literature on statistical dependence reveals that most assume symmetry in the sense that the strength of dependence of Xi on Xj exactly equals the strength of dependence of Xj on Xi. However, we show that such symmetry is often untrue in many real-world examples, being neither necessary nor sufficient. Vinod's…

利用深度生成模型与条件工具变量进行因果推断AI 解读

The instrumental variable (IV) approach is a widely used way to estimate the causal effects of a treatment on an outcome of interest from observational data with latent confounders. A standard IV is expected to be related to the treatment variable and independent of all other variables in the system. However, it is challenging to search for a standard IV from data directly due to the strict conditions. The conditional IV (CIV) method has been proposed to allow a variable to…

存在测量误差的连续处理效应的非参数估计AI 解读

We identify the average dose-response function (ADRF) for a continuously valued error-contaminated treatment by a weighted conditional expectation. We then estimate the weights nonparametrically by maximising a local generalised empirical likelihood subject to an expanding set of conditional moment equations incorporated into the deconvolution kernels. Thereafter, we construct a deconvolution kernel estimator of ADRF. We derive the asymptotic bias and variance of our ADRF…

连续时间随机过程的因果识别AI 解读

Many real-world processes are trajectories that may be regarded as continuous-time "functional data". Examples include patients' biomarker concentrations, environmental pollutant levels, and prices of stocks. Corresponding advances in data collection have yielded near continuous-time measurements, from e.g. physiological monitors, wearable digital devices, and environmental sensors. Statistical methodology for estimating the causal effect of a time-varying treatment,…

利用疾病—死亡脆弱性模型验证事件时间结局的替代终点AI 解读

A common practice in clinical trials is to evaluate a treatment effect on an intermediate endpoint when the true outcome of interest would be difficult or costly to measure. We consider how to validate intermediate endpoints in a causally-valid way when the trial outcomes are time-to-event. Using counterfactual outcomes, those that would be observed if the counterfactual treatment had been given, the causal association paradigm assesses the relationship of the treatment…

连续暴露测量有误时的因果暴露—反应函数估计：细颗粒物与全因死亡AI 解读

Numerous studies have examined the associations between long-term exposure to fine particulate matter (PM2.5) and adverse health outcomes. Recently, many of these studies have begun to employ high-resolution predicted PM2.5 concentrations, which are subject to measurement error. Previous approaches for exposure measurement error correction have either been applied in non-causal settings or have only considered a categorical exposure. Moreover, most procedures have failed to…

自适应试验设计的点估计（二）：实践考量与指南AI 解读

In adaptive clinical trials, the conventional end-of-trial point estimate of a treatment effect is prone to bias, that is, a systematic tendency to deviate from its true value. As stated in recent FDA guidance on adaptive designs, it is desirable to report estimates of treatment effects that reduce or remove this bias. However, it may be unclear which of the available estimators are preferable, and their use remains rare in practice. This paper is the second in a two-part…

自适应试验设计的点估计（一）：方法综述AI 解读

Recent FDA guidance on adaptive clinical trial designs defines bias as "a systematic tendency for the estimate of treatment effect to deviate from its true value", and states that it is desirable to obtain and report estimates of treatment effects that reduce or remove this bias. The conventional end-of-trial point estimates of the treatment effects are prone to bias in many adaptive designs, because they do not take into account the potential and realised trial adaptations.…

利用基线协变量分析罕见二元结局的小型整群随机试验AI 解读

Cluster-randomized trials (CRTs) involve randomizing entire groups of participants -- called clusters -- to treatment arms but are often comprised of a limited or fixed number of available clusters. While covariate adjustment can account for chance imbalances between treatment arms and increase statistical efficiency in individually-randomized trials, analytical methods for individual-level covariate adjustment in small CRTs have received little attention to date. In this…

合成主成分设计：利用合成控制快速平衡协变量AI 解读

The optimal design of experiments typically involves solving an NP-hard combinatorial optimization problem. In this paper, we aim to develop a globally convergent and practically efficient optimization algorithm. Specifically, we consider a setting where the pre-treatment outcome data is available and the synthetic control estimator is invoked. The average treatment effect is estimated via the difference between the weighted average outcomes of the treated and control units,…

利用自标准化矩的线性工具变量模型快速稳健推断AI 解读

We propose and implement an approach to inference in linear instrumental variables models which is simultaneously robust and computationally tractable. Inference is based on self-normalization of sample moment conditions, and allows for (but does not require) many (relative to the sample size), weak, potentially invalid or potentially endogenous instruments, as well as for many regressors and conditional heteroskedasticity. Our coverage results are uniform and can deliver a…

以半参数贝叶斯推断直接针对泛函参数AI 解读

Typical Bayesian inference requires parameter identification via likelihood parameterization, which has invited criticism for being less flexible than the Frequentist framework and subject to misspecification. Though misspecification may be avoided by functional parameter inference under a nonparametric model space, there does not exist a flexible Bayesian semiparametric model that would allow full control over the marginal prior over any general functional parameter. We…

结合协方差选择与阶数选择的因果向量自回归AI 解读

A causal vector autoregressive (CVAR) model is introduced for weakly stationary multivariate processes, combining a recursive directed graphical model for the contemporaneous components and a vector autoregressive model longitudinally. Block Cholesky decomposition with varying block sizes is used to solve the model equations and estimate the path coefficients along a directed acyclic graph (DAG). If the DAG is decomposable, i.e. the zeros form a reducible zero pattern (RZP)…

混合因果—非因果自回归模型的谱估计AI 解读

This paper investigates new ways of estimating and identifying causal, noncausal, and mixed causal-noncausal autoregressive models driven by a non-Gaussian error sequence. We do not assume any parametric distribution function for the innovations. Instead, we use the information of higher-order cumulants, combining the spectrum and the bispectrum in a minimum distance estimation. We show how to circumvent the nonlinearity of the parameters and the multimodality in the…

利用非高斯性估计因果有向无环图过程AI 解读

Numerous approaches have been proposed to discover causal dependencies in machine learning and data mining; among them, the state-of-the-art VAR-LiNGAM (short for Vector Auto-Regressive Linear Non-Gaussian Acyclic Model) is a desirable approach to reveal both the instantaneous and time-lagged relationships. However, all the obtained VAR matrices need to be analyzed to infer the final causal graph, leading to a rise in the number of parameters. To address this issue, we…

随机治疗成本约束下的个体化治疗规则AI 解读

Estimation and evaluation of individualized treatment rules have been studied extensively, but real-world treatment resource constraints have received limited attention in existing methods. We investigate a setting in which treatment is intervened upon based on covariates to optimize the mean counterfactual outcome under treatment cost constraints when the treatment cost is random. In a particularly interesting special case, an instrumental variable corresponding to…

因果聚合：基于约束的数据融合与联合干预效应推断AI 解读

In causal inference, it is common to estimate the causal effect of a single treatment variable on an outcome. However, practitioners may also be interested in the effect of simultaneous interventions on multiple covariates of a fixed target variable. We propose a novel method that allows to estimate the effect of joint interventions using data from different experiments in which only very few variables are manipulated. If there is only little randomized data or no randomized…

积极劳动市场政策的宏观效应：一种新的工具变量策略AI 解读

This study evaluates the macroeconomic effects of active labour market policies (ALMP) in Germany over the period 2005 to 2018. We propose a novel identification strategy to overcome the simultaneity of ALMP and labour market outcomes at the regional level. It exploits the imperfect overlap of local labour markets and local employment agencies that decide on the local implementation of policies. Specifically, we instrument for the use of ALMP in a local labour market with…

合成控制方法的渐近性质AI 解读

This paper provides new insights into the asymptotic properties of the synthetic control method (SCM). We show that the synthetic control (SC) weight converges to a limiting weight that minimizes the mean squared prediction risk of the treatment-effect estimator when the number of pretreatment periods goes to infinity, and we also quantify the rate of convergence. Observing the link between the SCM and model averaging, we further establish the asymptotic optimality of the SC…

基于分布变化的因果方向识别AI 解读

Mining genuine mechanisms underlying the complex data generation process in real-world systems is a fundamental step in promoting interpretability of, and thus trust in, data-driven models. Therefore, we propose a variation-based cause effect identification (VCEI) framework for causal discovery in bivariate systems from a single observational setting. Our framework relies on the principle of independence of cause and mechanism (ICM) under the assumption of an existing…

慈善捐赠调查中的情境老虎机：实验内结果与政策学习AI 解读

We design and implement an adaptive experiment (a ``contextual bandit'') to learn a targeted treatment assignment policy, where the goal is to use a participant's survey responses to determine which charity to expose them to in a donation solicitation. The design balances two competing objectives: optimizing the outcomes for the subjects in the experiment (``cumulative regret minimization'') and gathering data that will be most useful for policy learning, that is, for…

死亡截断与未测混杂下的因果推断AI 解读

Clinical studies sometimes encounter truncation by death, rendering outcomes undefined. Statistical analysis based solely on observed survivors may give biased results because the characteristics of survivors differ between treatment groups. By principal stratification, the survivor average causal effect was proposed as a causal estimand defined in always-survivors. However, this estimand is not identifiable when there is unmeasured confounding between the treatment…