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大规模数据因果推断的快速自助法算法AI 解读

Estimating causal effects from large experimental and observational data has become increasingly prevalent in both industry and research. The bootstrap is an intuitive and powerful technique used to construct standard errors and confidence intervals of estimators. Its application however can be prohibitively demanding in settings involving large data. In addition, modern causal inference estimators based on machine learning and optimization techniques exacerbate the…

在有向无环图中表示确定性变量：辅助识别与解释因果效应AI 解读

Deterministic variables are variables that are fully explained by one or more parent variables. They commonly arise when a variable has been algebraically constructed from one or more parent variables, as with composite variables, and in compositional data, where the 'whole' variable is determined from its 'parts'. This article introduces how deterministic variables may be depicted within directed acyclic graphs (DAGs) to help with identifying and interpreting causal effects…

依赖删失下治疗效应的析因生存分析AI 解读

Factorial analyses offer a powerful nonparametric means to detect main or interaction effects among multiple treatments. For survival outcomes, e.g. from clinical trials, such techniques can be adopted for comparing reasonable quantifications of treatment effects. The key difficulty to solve in survival analysis concerns the proper handling of censoring. So far, all existing factorial analyses for survival data were developed under the independent censoring assumption, which…

因果中位数差的混杂调整方法AI 解读

With continuous outcomes, the average causal effect is typically defined using a contrast of expected potential outcomes. However, in the presence of skewed outcome data, the expectation may no longer be meaningful. In practice the typical approach is to either "ignore or transform" - ignore the skewness altogether or transform the outcome to obtain a more symmetric distribution, although neither approach is entirely satisfactory. Alternatively the causal effect can be…

利用观测数据进行分布鲁棒因果推断AI 解读

We consider the estimation of average treatment effects in observational studies and propose a new framework of robust causal inference with unobserved confounders. Our approach is based on distributionally robust optimization and proceeds in two steps. We first specify the maximal degree to which the distribution of unobserved potential outcomes may deviate from that of observed outcomes. We then derive sharp bounds on the average treatment effects under this assumption.…

基于梯度提升树的异质性处理效应增广学习AI 解读

Heterogeneous treatment effects (HTE) based on patients' genetic or clinical factors are of significant interest to precision medicine. Simultaneously modeling HTE and corresponding main effects for randomized clinical trials with high-dimensional predictive markers is challenging. Motivated by the modified covariates approach, we propose a two-stage statistical learning procedure for estimating HTE with optimal efficiency augmentation, generalizing to arbitrary interaction…

混杂情形下离策略评估的工具变量方法AI 解读

Off-policy evaluation (OPE) is a method for estimating the return of a target policy using some pre-collected observational data generated by a potentially different behavior policy. In some cases, there may be unmeasured variables that can confound the action-reward or action-next-state relationships, rendering many existing OPE approaches ineffective. This paper develops an instrumental variable (IV)-based method for consistent OPE in confounded Markov decision processes…

用机器学习测量气候适应AI 解读

I measure adaptation to climate change by comparing elasticities from short-run and long-run changes in damaging weather. I propose a debiased machine learning approach to flexibly measure these elasticities in panel settings. In a simulation exercise, I show that debiased machine learning has considerable benefits relative to standard machine learning or ordinary least squares, particularly in high-dimensional settings. I then measure adaptation to damaging heat exposure in…

因果效应估计：近期进展、挑战与机会AI 解读

Causal inference has numerous real-world applications in many domains, such as health care, marketing, political science, and online advertising. Treatment effect estimation, a fundamental problem in causal inference, has been extensively studied in statistics for decades. However, traditional treatment effect estimation methods may not well handle large-scale and high-dimensional heterogeneous data. In recent years, an emerging research direction has attracted increasing…

何时可以忽略运行变量中的测量误差AI 解读

In many applications of regression discontinuity designs, the running variable used by the administrator to assign treatment is only observed with error. We show that, provided the observed running variable (i) correctly classifies the treatment assignment, and (ii) affects the conditional means of the potential outcomes smoothly, ignoring the measurement error nonetheless yields an estimate with a causal interpretation: the average treatment effect for units whose observed…

存在地区干扰时的政策相关因果效应估计：费城饮料税应用AI 解读

To comprehensively evaluate a public policy intervention, researchers must consider the effects of the policy not just on the implementing region, but also nearby, indirectly-affected regions. For example, an excise tax on sweetened beverages in Philadelphia was shown to not only be associated with a decrease in volume sales of taxed beverages in Philadelphia, but also an increase in sales in bordering counties not subject to the tax. The latter association may be explained…

利用零效应降低单侧触发实验中的估计方差AI 解读

In online experiments where the intervention is only exposed, or "triggered", for a small subset of the population, it is critical to use variance reduction techniques to estimate treatment effects with sufficient precision to inform business decisions. Trigger-dilute analysis is often used in these situations, and reduces the sampling variance of overall intent-to-treat (ITT) effects by an order of magnitude equal to the inverse of the triggering rate; for example, a…

将排除未启动治疗者的修正意向治疗分析解释为主层估计AI 解读

Background: A common intercurrent event affecting many trials is when some participants do not begin their assigned treatment. Many trials use a modified intention-to-treat (mITT) approach, whereby participants who do not initiate treatment are excluded from the analysis. However, it is not clear the estimand being targeted by such an approach or the assumptions necessary for it to be unbiased. Methods: We demonstrate that a mITT analysis which excludes participants who do…

聚类观察性数据中未测混杂下因果处理效应估计的敏感性分析AI 解读

Identifying causal treatment (or exposure) effects in observational studies requires the data to satisfy the unconfoundedness assumption which is not testable using the observed data. With sensitivity analysis, one can determine how the conclusions might change if assumptions are violated to a certain degree. In this paper, we propose a new technique for sensitivity analysis applicable to clusters observational data with a normally distributed or binary outcome. The proposed…

面板数据的异质性合成学习器AI 解读

In the new era of personalization, learning the heterogeneous treatment effect (HTE) becomes an inevitable trend with numerous applications. Yet, most existing HTE estimation methods focus on independently and identically distributed observations and cannot handle the non-stationarity and temporal dependency in the common panel data setting. The treatment evaluators developed for panel data, on the other hand, typically ignore the individualized information. To fill the gap,…

CAPITAL：通过约束政策树搜索识别最优子群体AI 解读

Personalized medicine, a paradigm of medicine tailored to a patient's characteristics, is an increasingly attractive field in health care. An important goal of personalized medicine is to identify a subgroup of patients, based on baseline covariates, that benefits more from the targeted treatment than other comparative treatments. Most of the current subgroup identification methods only focus on obtaining a subgroup with an enhanced treatment effect without paying attention…

通过贝叶斯线性规划控制信号发现与定位AI 解读

Scientists often must simultaneously localize and discover signals. For instance, in genetic fine-mapping, high correlations between nearby genetic variants make it hard to identify the exact locations of causal variants. So the statistical task is to output as many disjoint regions containing a signal as possible, each as small as possible, while controlling false positives. Similar problems arise in any application where signals cannot be perfectly localized, such as…

回归不连续设计中的视觉推断与图形呈现AI 解读

Despite the widespread use of graphs in empirical research, little is known about readers' ability to process the statistical information they are meant to convey ("visual inference"). We study visual inference within the context of regression discontinuity (RD) designs by measuring how accurately readers identify discontinuities in graphs produced from data generating processes calibrated on 11 published papers from leading economics journals. First, we assess the effects…

因果量的 ε 可识别性AI 解读

Identifying the effects of causes and causes of effects is vital in virtually every scientific field. Often, however, the needed probabilities may not be fully identifiable from the data sources available. This paper shows how partial identifiability is still possible for several probabilities of causation. We term this epsilon-identifiability and demonstrate its usefulness in cases where the behavior of certain subpopulations can be restricted to within some narrow bounds.…

从自激与互激时间序列中发现因果图AI 解读

We present a generalized linear structural causal model, coupled with a novel data-adaptive linear regularization, to recover causal directed acyclic graphs (DAGs) from time series. By leveraging a recently developed stochastic monotone Variational Inequality (VI) formulation, we cast the causal discovery problem as a general convex optimization. Furthermore, we develop a non-asymptotic recovery guarantee and quantifiable uncertainty by solving a linear program to establish…

用于有效因果推断的卷积神经网络AI 解读

Convolutional neural networks (CNN) have been successful in machine learning applications. Their success relies on their ability to consider space invariant local features. We consider the use of CNN to fit nuisance models in semiparametric estimation of the average causal effect of a treatment. In this setting, nuisance models are functions of pre-treatment covariates that need to be controlled for. In an application where we want to estimate the effect of early retirement…

Ananke：基于图模型的因果推断 Python 软件包AI 解读

We implement Ananke: an object-oriented Python package for causal inference with graphical models. At the top of our inheritance structure is an easily extensible Graph class that provides an interface to several broadly useful graph-based algorithms and methods for visualization. We use best practices of object-oriented programming to implement subclasses of the Graph superclass that correspond to types of causal graphs that are popular in the current literature. This…

存在隐含中介变量时的因果推断AI 解读

Proximal causal inference was recently proposed as a framework to identify causal effects from observational data in the presence of hidden confounders for which proxies are available. In this paper, we extend the proximal causal inference approach to settings where identification of causal effects hinges upon a set of mediators which are not observed, yet error prone proxies of the hidden mediators are measured. Specifically, (i) We establish causal hidden mediation…

双重稳健因果推断中的变量选择AI 解读

Confounding control is crucial and yet challenging for causal inference based on observational studies. Under the typical unconfoundness assumption, augmented inverse probability weighting (AIPW) has been popular for estimating the average causal effect (ACE) due to its double robustness in the sense it relies on either the propensity score model or the outcome mean model to be correctly specified. To ensure the key assumption holds, the effort is often made to collect a…