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离散化时间尺度在连续时间处理因果推断中的作用AI 解读

There are well-established methods for identifying the causal effect of a time-varying treatment applied at discrete time points. However, in the real world, many treatments are continuous or have a finer time scale than the one used for measurement or analysis. While researchers have investigated the discrepancies between estimates under varying discretization scales using simulations and empirical data, it is still unclear how the choice of discretization scale affects…

固定短时间维度面板中的简单双重差分估计AI 解读

The present paper proposes a new treatment effects estimator that is valid when the number of time periods is small, and the parallel trends condition holds conditional on covariates and unobserved heterogeneity in the form of interactive fixed effects. The estimator also allow the control variables to be affected by treatment and it enables estimation of the resulting indirect effect on the outcome variable. The asymptotic properties of the estimator are established and…

因果剂量响应函数的非参数推断方法AI 解读

The causal dose response curve is commonly selected as the statistical parameter of interest in studies where the goal is to understand the effect of a continuous exposure on an outcome.Most of the available methodology for statistical inference on the dose-response function in the continuous exposure setting requires strong parametric assumptions on the probability distribution. Such parametric assumptions are typically untenable in practice and lead to invalid inference.…

ACE：昂贵实验中因果推断的主动学习AI 解读

Experiments are the gold standard for causal inference. In many applications, experimental units can often be recruited or chosen sequentially, and the adaptive execution of such experiments may offer greatly improved inference of causal quantities over non-adaptive approaches, particularly when experiments are expensive. We thus propose a novel active learning method called ACE (Active learning for Causal inference with Expensive experiments), which leverages Gaussian…

隐藏混杂下剂量响应的部分识别AI 解读

Inferring causal effects of continuous-valued treatments from observational data is a crucial task promising to better inform policy- and decision-makers. A critical assumption needed to identify these effects is that all confounding variables -- causal parents of both the treatment and the outcome -- are included as covariates. Unfortunately, given observational data alone, we cannot know with certainty that this criterion is satisfied. Sensitivity analyses provide…

用于条件效应及其他线性泛函估计的三路交叉拟合与伪结果回归AI 解读

We propose an approach to better inform treatment decisions at an individual level by adapting recent advances in average treatment effect estimation to conditional average treatment effect estimation. Our work is based on doubly robust estimation methods, which combine flexible machine learning tools to produce efficient effect estimates while relaxing parametric assumptions about the data generating process. Refinements to doubly robust methods have achieved faster…

存在部分处理转移者时，基于工具变量估计完整处理效应AI 解读

The effect of the full treatment is a primary parameter of interest in policy evaluation, while often only the effect of a subset of treatment is estimated. We partially identify the local average treatment effect of receiving full treatment (LAFTE) using an instrumental variable that may induce individuals into only a subset of treatment (movers). We show that movers violate the standard exclusion restriction, necessary conditions on the presence of movers are testable, and…

高维数据的渐近分布无关独立性检验AI 解读

Test of independence is of fundamental importance in modern data analysis, with broad applications in variable selection, graphical models, and causal inference. When the data is high dimensional and the potential dependence signal is sparse, independence testing becomes very challenging without distributional or structural assumptions. In this paper, we propose a general framework for independence testing by first fitting a classifier that distinguishes the joint and…

存在空间溢出的双重差分估计AI 解读

Empirical work often uses treatment assigned following geographic boundaries. When the effects of treatment cross over borders, classical difference-in-differences estimation produces biased estimates for the average treatment effect. In this paper, I introduce a potential outcomes framework to model spillover effects and decompose the estimate's bias in two parts: (1) the control group no longer identifies the counterfactual trend because their outcomes are affected by…

利用辅助数据提高在线教育平台 A/B 测试的分析精度：新数据与新结果AI 解读

Randomized A/B tests within online learning platforms represent an exciting direction in learning sciences. With minimal assumptions, they allow causal effect estimation without confounding bias and exact statistical inference even in small samples. However, often experimental samples and/or treatment effects are small, A/B tests are underpowered, and effect estimates are overly imprecise. Recent methodological advances have shown that power and statistical precision can be…

因果效应估计的交叉矩方法AI 解读

We consider the problem of estimating the causal effect of a treatment on an outcome in linear structural causal models (SCM) with latent confounders when we have access to a single proxy variable. Several methods (such as difference-in-difference (DiD) estimator or negative outcome control) have been proposed in this setting in the literature. However, these approaches require either restrictive assumptions on the data generating model or having access to at least two proxy…

通过矩阵加权线性估计量融合观测与干预数据估计因果效应AI 解读

We study causal effect estimation from a mixture of observational and interventional data in a confounded linear regression model with multivariate treatments. We show that the statistical efficiency in terms of expected squared error can be improved by combining estimators arising from both the observational and interventional setting. To this end, we derive methods based on matrix weighted linear estimators and prove that our methods are asymptotically unbiased in the…

随机对照试验中协变量调整的使用：综述AI 解读

There has been a growing interest in covariate adjustment in the analysis of randomized controlled trials in past years. For instance, the U.S. Food and Drug Administration recently issued guidance that emphasizes the importance of distinguishing between conditional and marginal treatment effects. Although these effects coincide in linear models, this is not typically the case in other settings, and this distinction is often overlooked in clinical trial practice. Considering…

预算约束下的 PAC-Bayes 处理分配AI 解读

This paper considers the estimation of treatment assignment rules when the policy maker faces a general budget or resource constraint. Utilizing the PAC-Bayesian framework, we propose new treatment assignment rules that allow for flexible notions of treatment outcome, treatment cost, and a budget constraint. For example, the constraint setting allows for cost-savings, when the costs of non-treatment exceed those of treatment for a subpopulation, to be factored into the…

结果依赖型缺失与自我删失下的因果推断AI 解读

We consider missingness in the context of causal inference when the outcome of interest may be missing. If the outcome directly affects its own missingness status, i.e., it is "self-censoring", this may lead to severely biased causal effect estimates. Miao et al. [2015] proposed the shadow variable method to correct for bias due to self-censoring; however, verifying the required model assumptions can be difficult. Here, we propose a test based on a randomized incentive…

面向特定任务的处理效应估计实验设计AI 解读

Understanding causality should be a core requirement of any attempt to build real impact through AI. Due to the inherent unobservability of counterfactuals, large randomised trials (RCTs) are the standard for causal inference. But large experiments are generically expensive, and randomisation carries its own costs, e.g. when suboptimal decisions are trialed. Recent work has proposed more sample-efficient alternatives to RCTs, but these are not adaptable to the downstream…

结合支持集不重叠的观察数据与实验数据估计处理效应AI 解读

When estimating treatment effects, the golden standard is to conduct a randomized experiment and then contrast outcomes associated with the treatment group and the control group. However, in many cases, randomized experiments are either conducted with a much smaller scale compared to the size of the target population or accompanied with certain ethical issues and thus hard to implement. Therefore, researchers usually rely on observational data to study causal connections.…

利用混合人群试验评估生物标志物亚组疗效的贝叶斯元分析AI 解读

During drug development, evidence can emerge to suggest a treatment is more effective in a specific patient subgroup. Whilst early trials may be conducted in biomarker-mixed populations, later trials are more likely to enrol biomarker-positive patients alone, thus leading to trials of the same treatment investigated in different populations. When conducting a meta-analysis, a conservative approach would be to combine only trials conducted in the biomarker-positive subgroup.…

理解异质性处理效应估计中的模型选择困境AI 解读

Personalized treatment effect estimates are often of interest in high-stakes applications -- thus, before deploying a model estimating such effects in practice, one needs to be sure that the best candidate from the ever-growing machine learning toolbox for this task was chosen. Unfortunately, due to the absence of counterfactual information in practice, it is usually not possible to rely on standard validation metrics for doing so, leading to a well-known model selection…

实验中利用机器学习推断处理效应方差的稳健方法AI 解读

Experimenters often collect baseline data to study heterogeneity. I propose the first valid confidence intervals for the VCATE, the treatment effect variance explained by observables. Conventional approaches yield incorrect coverage when the VCATE is zero. As a result, practitioners could be prone to detect heterogeneity even when none exists. The reason why coverage worsens at the boundary is that all efficient estimators have a locally-degenerate influence function and may…

异质性处理效应的因果保序校准AI 解读

We propose causal isotonic calibration, a novel nonparametric method for calibrating predictors of heterogeneous treatment effects. Furthermore, we introduce cross-calibration, a data-efficient variant of calibration that eliminates the need for hold-out calibration sets. Cross-calibration leverages cross-fitted predictors and generates a single calibrated predictor using all available data. Under weak conditions that do not assume monotonicity, we establish that both causal…

个体处理效应估计的迁移学习AI 解读

This work considers the problem of transferring causal knowledge between tasks for Individual Treatment Effect (ITE) estimation. To this end, we theoretically assess the feasibility of transferring ITE knowledge and present a practical framework for efficient transfer. A lower bound is introduced on the ITE error of the target task to demonstrate that ITE knowledge transfer is challenging due to the absence of counterfactual information. Nevertheless, we establish…

模糊动态治疗方案：强化学习方法AI 解读

A main research goal in various studies is to use an observational data set and provide a new set of counterfactual guidelines that can yield causal improvements. Dynamic Treatment Regimes (DTRs) are widely studied to formalize this process. However, available methods in finding optimal DTRs often rely on assumptions that are violated in real-world applications (e.g., medical decision-making or public policy), especially when (a) the existence of unobserved confounders…

竞争风险观察研究中平均处理效应重抽样过程的渐近性质AI 解读

In observational studies with time-to-event outcomes, the g-formula can be used to estimate a treatment effect in the presence of confounding factors. However, the asymptotic distribution of the corresponding stochastic process is complicated and thus not suitable for deriving confidence intervals or time-simultaneous confidence bands for the average treatment effect. A common remedy are resampling-based approximations, with Efron's nonparametric bootstrap being the standard…