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成对关系数据核密度估计的一致推断AI 解读

Dyadic data is often encountered when quantities of interest are associated with the edges of a network. As such it plays an important role in statistics, econometrics and many other data science disciplines. We consider the problem of uniformly estimating a dyadic Lebesgue density function, focusing on nonparametric kernel-based estimators taking the form of dyadic empirical processes. Our main contributions include the minimax-optimal uniform convergence rate of the dyadic…

Clip-OGD：序贯实验中自适应 Neyman 分配的实验设计AI 解读

From clinical development of cancer therapies to investigations into partisan bias, adaptive sequential designs have become increasingly popular method for causal inference, as they offer the possibility of improved precision over their non-adaptive counterparts. However, even in simple settings (e.g. two treatments) the extent to which adaptive designs can improve precision is not sufficiently well understood. In this work, we study the problem of Adaptive Neyman Allocation…

平滑工具变量分位数回归AI 解读

In this article, I introduce the sivqr command, which estimates the coefficients of the instrumental variables (IV) quantile regression model introduced by Chernozhukov and Hansen (2005). The sivqr command offers several advantages over the existing ivqreg and ivqreg2 commands for estimating this IV quantile regression model, which complements the alternative "triangular model" behind cqiv and the "local quantile treatment effect" model of ivqte. Computationally, sivqr…

最小假设下含协变量的断点回归平均处理效应估计AI 解读

We study regression discontinuity designs with the use of additional covariates for estimation of the average treatment effect. We provide a detailed proof of asymptotic normality of the covariate-adjusted estimator under minimal assumptions, which may serve as an accessible text to the mathematics behind regression discontinuity with covariates. In addition, this proof carries at least three benefits. First of all, it allows to draw straightforward consequences concerning…

因果推断中的双重下降与单调下降：高维合成控制应用AI 解读

Motivated by a recent literature on the double-descent phenomenon in machine learning, we consider highly over-parameterized models in causal inference, including synthetic control with many control units. In such models, there may be so many free parameters that the model fits the training data perfectly. We first investigate high-dimensional linear regression for imputing wage data and estimating average treatment effects, where we find that models with many more…

基线子组及相关分析的设计型随机试验估计量与中心极限定理AI 解读

There is a growing literature on design-based methods to estimate average treatment effects (ATEs) for randomized controlled trials (RCTs) for full sample analyses. This article extends these methods to estimate ATEs for discrete subgroups defined by pre-treatment variables, with an application to an RCT testing subgroup effects for a school voucher experiment in New York City. We consider ratio estimators for subgroup effects using regression methods, allowing for model…

网络合成干预：网络干扰下的面板数据因果框架AI 解读

We propose a generalization of the synthetic controls and synthetic interventions methodology to incorporate network interference. We consider the estimation of unit-specific potential outcomes from panel data in the presence of spillover across units and unobserved confounding. Key to our approach is a novel latent factor model that takes into account network interference and generalizes the factor models typically used in panel data settings. We propose an estimator,…

通过多重插补实现因果推断中的 G 公式AI 解读

G-formula is a popular approach for estimating treatment or exposure effects from longitudinal data that are subject to time-varying confounding. G-formula estimation is typically performed by Monte-Carlo simulation, with non-parametric bootstrapping used for inference. We show that G-formula can be implemented by exploiting existing methods for multiple imputation (MI) for synthetic data. This involves using an existing modified version of Rubin's variance estimator. In…

无需正值性假设的观察数据政策学习AI 解读

Policy learning utilizing observational data is pivotal across various domains, with the objective of learning the optimal treatment assignment policy while adhering to specific constraints such as fairness, budget, and simplicity. This study introduces a novel positivity-free (stochastic) policy learning framework designed to address the challenges posed by the impracticality of the positivity assumption in real-world scenarios. This framework leverages incremental…

超高维混杂变量选择算法比较及影像组学应用AI 解读

Radiomics is an emerging area of medical imaging data analysis particularly for cancer. It involves the conversion of digital medical images into mineable ultra-high dimensional data. Machine learning algorithms are widely used in radiomics data analysis to develop powerful decision support model to improve precision in diagnosis, assessment of prognosis and prediction of therapy response. However, machine learning algorithms for causal inference have not been previously…

处理选择、均方遗憾与部分识别AI 解读

We consider a decision maker who faces a binary treatment choice when their welfare is only partially identified from data. We contribute to the literature by anchoring our finite-sample analysis on mean square regret, a decision criterion advocated by Kitagawa, Lee, and Qiu (2022). We find that optimal rules are always fractional, irrespective of the width of the identified set and precision of its estimate. The optimal treatment fraction is a simple logistic transformation…

从时间序列学习领域特定的因果发现方法AI 解读

Causal discovery (CD) from time-varying data is important in neuroscience, medicine, and machine learning. Techniques for CD encompass randomized experiments, which are generally unbiased but expensive, and algorithms such as Granger causality, conditional-independence-based, structural-equation-based, and score-based methods that are only accurate under strong assumptions made by human designers. However, as demonstrated in other areas of machine learning, human expertise…

非比例风险下生存分析统计方法的中立比较AI 解读

While well-established methods for time-to-event data are available when the proportional hazards assumption holds, there is no consensus on the best inferential approach under non-proportional hazards (NPH). However, a wide range of parametric and non-parametric methods for testing and estimation in this scenario have been proposed. To provide recommendations on the statistical analysis of clinical trials where non proportional hazards are expected, we conducted a…

用数论将无限时间序列图投影为有限边际图AI 解读

In recent years, a growing number of method and application works have adapted and applied the causal-graphical-model framework to time series data. Many of these works employ time-resolved causal graphs that extend infinitely into the past and future and whose edges are repetitive in time, thereby reflecting the assumption of stationary causal relationships. However, most results and algorithms from the causal-graphical-model framework are not designed for infinite graphs.…

整群随机试验中的混合模型协方差分析AI 解读

In the analyses of cluster-randomized trials, mixed-model analysis of covariance (ANCOVA) is a standard approach for covariate adjustment and handling within-cluster correlations. However, when the normality, linearity, or the random-intercept assumption is violated, the validity and efficiency of the mixed-model ANCOVA estimators for estimating the average treatment effect remain unclear. Under the potential outcomes framework, we prove that the mixed-model ANCOVA…

一类潜在结果模型的识别与估计AI 解读

This paper develops a class of potential outcomes models characterized by three main features: (i) Unobserved heterogeneity can be represented by a vector of potential outcomes and a type describing the manner in which an instrument determines the choice of treatment; (ii) The availability of an instrumental variable that is conditionally independent of unobserved heterogeneity; and (iii) The imposition of convex restrictions on the distribution of unobserved heterogeneity.…

未知加性干预下高斯潜变量因果模型的学习与评分AI 解读

With observational data alone, causal structure learning is a challenging problem. The task becomes easier when having access to data collected from perturbations of the underlying system, even when the nature of these is unknown. Existing methods either do not allow for the presence of latent variables or assume that these remain unperturbed. However, these assumptions are hard to justify if the nature of the perturbations is unknown. We provide results that enable scoring…

边际处理效应估计：何时标准化优于倾向得分加权？AI 解读

In light of newly developed standardization methods, we evaluate, via simulation study, how propensity score weighting and standardization -based approaches compare for obtaining estimates of the marginal odds ratio and the marginal hazard ratio. Specifically, we consider how the two approaches compare in two different scenarios: (1) in a single observational study, and (2) in an anchored indirect treatment comparison (ITC) of randomized controlled trials. We present the…

生存分析中的时变中介：因果假设的图形表示AI 解读

We study time-dependent mediators in survival analysis using a treatment separation approach due to Didelez [2019] and based on earlier work by Robins and Richardson [2011]. This approach avoids nested counterfactuals and crossworld assumptions which are otherwise common in mediation analysis. The causal model of treatment, mediators, covariates, confounders and outcome is represented by causal directed acyclic graphs (DAGs). However, the DAGs tend to be very complex when we…

全基因组关联研究中 GhostKnockoffs 的稳健推断AI 解读

Genome-wide association studies (GWASs) have been extensively adopted to depict the underlying genetic architecture of complex diseases. Motivated by GWASs' limitations in identifying small effect loci to understand complex traits' polygenicity and fine-mapping putative causal variants from proxy ones, we propose a knockoff-based method which only requires summary statistics from GWASs and demonstrate its validity in the presence of relatedness. We show that GhostKnockoffs…

目标人群处理效应的联邦自适应因果估计（FACE）AI 解读

Federated learning of causal estimands may greatly improve estimation efficiency by leveraging data from multiple study sites, but robustness to heterogeneity and model misspecifications is vital for ensuring validity. We develop a Federated Adaptive Causal Estimation (FACE) framework to incorporate heterogeneous data from multiple sites to provide treatment effect estimation and inference for a flexibly specified target population of interest. FACE accounts for site-level…

含潜在混杂的时间序列因果祖先图刻画AI 解读

In this paper, we introduce a novel class of graphical models for representing time lag specific causal relationships and independencies of multivariate time series with unobserved confounders. We completely characterize these graphs and show that they constitute proper subsets of the currently employed model classes. As we show, from the novel graphs one can thus draw stronger causal inferences -- without additional assumptions. We further introduce a graphical…

部分指定的因果模拟AI 解读

Simulation studies play a key role in the validation of causal inference methods. The simulation results are reliable only if the study is designed according to the promised operational conditions of the method-in-test. Still, many causal inference literature tend to design over-restricted or misspecified studies. In this paper, we elaborate on the problem of improper simulation design for causal methods and compile a list of desiderata for an effective simulation framework.…

完全随机化与计算机辅助平衡设计下的样本依从者平均因果效应推断AI 解读

Non-compliance is common in real world experiments. We focus on inference about the sample complier average causal effect, that is, the average treatment effect for experimental units who are compliers. We present three types of inference strategies for the sample complier average causal effect: the Wald estimator, regression adjustment estimators and model-based Bayesian inference. Because modern computer assisted experimental designs have been used to improve covariate…