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回归不连续设计中远离阈值的效应外推AI 解读

Canonical RD designs yield credible local estimates of the treatment effect at the cutoff under mild continuity assumptions, but they fail to identify treatment effects away from the cutoff without additional assumptions. The fundamental challenge of identifying treatment effects away from the cutoff is that the counterfactual outcome under the alternative treatment status is never observed. This paper aims to provide a methodological blueprint to identify treatment effects…

回归调整的收益上限AI 解读

Regression adjustment, sometimes known as Controlled-experiment Using Pre-Experiment Data (CUPED), is an important technique in internet experimentation. It decreases the variance of effect size estimates, often cutting confidence interval widths in half or more while never making them worse. It does so by carefully regressing the goal metric against pre-experiment features to reduce the variance. The tremendous gains of regression adjustment begs the question: How much…

基于风险的决策：干预下序贯预测的估计目标AI 解读

Prediction models are used amongst others to inform medical decisions on interventions. Typically, individuals with high risks of adverse outcomes are advised to undergo an intervention while those at low risk are advised to refrain from it. Standard prediction models do not always provide risks that are relevant to inform such decisions: e.g., an individual may be estimated to be at low risk because similar individuals in the past received an intervention which lowered…

完全随机实验中样本依从者平均因果效应的推断AI 解读

In randomized experiments with non-compliance scholars have argued that the complier average causal effect (CACE) ought to be the main causal estimand. The literature on inference of the complier average treatment effect (CACE) has focused on inference about the population CACE. However, in general individuals in the experiments are volunteers. This means that there is a risk that individuals partaking in a given experiment differ in important ways from a population of…

对照治疗臂发生变更时的平台试验设计AI 解读

Platform trials are a more efficient way of testing multiple treatments compared to running separate trials. In this paper we consider platform trials where, if a treatment is found to be superior to the control, it will become the new standard of care (and the control in the platform). The remaining treatments are then tested against this new control. In such a setting, one can either keep the information on both the new standard of care and the other active treatments…

从高维观察性研究中学习变异来源AI 解读

Causal inference studies whether the presence of a variable influences an observed outcome. As measured by quantities such as the "average treatment effect," this paradigm is employed across numerous biological fields, from vaccine and drug development to policy interventions. Unfortunately, the majority of these methods are often limited to univariate outcomes. Our work generalizes causal estimands to outcomes with any number of dimensions or any measurable space, and…

因果推断中的深度学习入门AI 解读

This review systematizes the emerging literature for causal inference using deep neural networks under the potential outcomes framework. It provides an intuitive introduction on how deep learning can be used to estimate/predict heterogeneous treatment effects and extend causal inference to settings where confounding is non-linear, time varying, or encoded in text, networks, and images. To maximize accessibility, we also introduce prerequisite concepts from causal inference…

利用排名加权平均处理效应评估处理优先规则AI 解读

There are a number of available methods for selecting whom to prioritize for treatment, including ones based on treatment effect estimation, risk scoring, and hand-crafted rules. We propose rank-weighted average treatment effect (RATE) metrics as a simple and general family of metrics for comparing and testing the quality of treatment prioritization rules. RATE metrics are agnostic as to how the prioritization rules were derived, and only assess how well they identify…

多值处理观察性研究中的目标学习：抗精神病药物治疗安全性评估AI 解读

We investigate estimation of causal effects of multiple competing (multi-valued) treatments in the absence of randomization. Our work is motivated by an intention-to-treat study of the relative cardiometabolic risk of assignment to one of six commonly prescribed antipsychotic drugs in a cohort of nearly 39,000 adults with serious mental illnesses. Doubly-robust estimators, such as targeted minimum loss-based estimation (TMLE), require correct specification of either the…

通过因果信息最小化对多模态模型去偏AI 解读

Most existing debiasing methods for multimodal models, including causal intervention and inference methods, utilize approximate heuristics to represent the biases, such as shallow features from early stages of training or unimodal features for multimodal tasks like VQA, etc., which may not be accurate. In this paper, we study bias arising from confounders in a causal graph for multimodal data and examine a novel approach that leverages causally-motivated information…

分位数处理效应、秩相似性与工具变量变异AI 解读

This paper investigates how certain relationship between observed and counterfactual distributions serves as an identifying condition for treatment effects when the treatment is endogenous, and shows that this condition holds in a range of nonparametric models for treatment effects. To this end, we first provide a novel characterization of the prevalent assumption restricting treatment heterogeneity in the literature, namely rank similarity. Our characterization demonstrates…

网络干扰下社交网络 A/B 测试的协方差优化设计AI 解读

Online A/B tests have become increasingly popular and important for social platforms. However, accurately estimating the global average treatment effect (GATE) has proven to be challenging due to network interference, which violates the Stable Unit Treatment Value Assumption (SUTVA) and poses a great challenge to experimental design. Existing network experimental design research was mostly based on the unbiased Horvitz-Thompson (HT) estimator with substantial data trimming…

条件处理效应分布的部分识别与推断AI 解读

This paper considers identification and inference for the distribution of treatment effects conditional on observable covariates. Since the conditional distribution of treatment effects is not point identified without strong assumptions, we obtain bounds on the conditional distribution of treatment effects by using the Makarov bounds. We also consider the case where the treatment is endogenous and propose two stochastic dominance assumptions to tighten the bounds. We develop…

基于观测医疗数据构建可迁移因果网络模型AI 解读

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models are almost always affected by biases that can strongly impact the outcomes validity: two examples are values missing not-at-random and selection bias. Addressing them is a key element in achieving transportability and in studying the…

多变量纵向数据因果推断的张量补全：重新评估疫情管制措施AI 解读

We propose a new method that uses tensor completion to estimate causal effects with multivariate longitudinal data, data in which multiple outcomes are observed for each unit and time period. Our motivation is to estimate the number of COVID-19 fatalities prevented by government mandates such as travel restrictions, mask-wearing directives, and vaccination requirements. In addition to COVID-19 fatalities, we observe related outcomes such as the number of fatalities from…

多尺度非平稳因果结构学习AI 解读

This paper addresses a gap in the current state of the art by providing a solution for modeling causal relationships that evolve over time and occur at different time scales. Specifically, we introduce the multiscale non-stationary directed acyclic graph (MN-DAG), a framework for modeling multivariate time series data. Our contribution is twofold. Firstly, we expose a probabilistic generative model by leveraging results from spectral and causality theories. Our model allows…

基于变分图自编码器的无概念标签因果解耦AI 解读

In disentangled representation learning, the goal is to achieve a compact representation that consists of all interpretable generative factors in the observational data. Learning disentangled representations for graphs becomes increasingly important as graph data rapidly grows. Existing approaches often rely on Variational Auto-Encoder (VAE) or its causal structure learning-based refinement, which suffer from sub-optimality in VAEs due to the independence factor assumption…

离散时间序列与神经脉冲序列的时间因果发现检验AI 解读

We consider the problem of detecting causal relationships between discrete time series, in the presence of potential confounders. A hypothesis test is introduced for identifying the temporally causal influence of $(x_n)$ on $(y_n)$, causally conditioned on a possibly confounding third time series $(z_n)$. Under natural Markovian modeling assumptions, it is shown that the null hypothesis, corresponding to the absence of temporally causal influence, is equivalent to the…

混杂变量维度增长时利用神经网络推断一般处理效应AI 解读

Semiparametric efficient estimation of various multi-valued causal effects, including quantile treatment effects, is important in economic, biomedical, and other social sciences. Under the unconfoundedness condition, adjustment for confounders requires estimating the nuisance functions relating outcome or treatment to confounders nonparametrically. This paper considers a generalized optimization framework for efficient estimation of general treatment effects using artificial…

随机实验中一般回归调整的去相关方法AI 解读

We study regression adjustment with general function class approximations for estimating the average treatment effect in the design-based setting. Standard regression adjustment involves bias due to sample re-use, and this bias leads to behavior that is sub-optimal in the sample size, and/or imposes restrictive assumptions. Our main contribution is to introduce a novel decorrelation-based approach that circumvents these issues. We prove guarantees, both asymptotic and…

利用最优传输估计潜在结果联合分布的泛函AI 解读

Many causal parameters depend on a moment of the joint distribution of potential outcomes. Such parameters are especially relevant in policy evaluation settings, where noncompliance is common and accommodated through the model of Imbens & Angrist (1994). This paper shows that the sharp identified set for these parameters is an interval with endpoints characterized by the value of optimal transport problems. Sample analogue estimators are proposed based on the dual problem of…

反事实结果的正交预测AI 解读

Orthogonal meta-learners, such as DR-learner, R-learner and IF-learner, are increasingly used to estimate conditional average treatment effects. They improve convergence rates relative to naïve meta-learners (e.g., T-, S- and X-learner) through de-biasing procedures that involve applying standard learners to specifically transformed outcome data. This leads them to disregard the possibly constrained outcome space, which can be particularly problematic for dichotomous…

合并多项随机试验估计异质性处理效应的方法比较AI 解读

Individualized treatment decisions can improve health outcomes, but using data to make these decisions in a reliable, precise, and generalizable way is challenging with a single dataset. Leveraging multiple randomized controlled trials allows for the combination of datasets with unconfounded treatment assignment to better estimate heterogeneous treatment effects. This paper discusses several non-parametric approaches for estimating heterogeneous treatment effects using data…

含零值时如何取对数？若干问题与解决办法AI 解读

When studying an outcome $Y$ that is weakly-positive but can equal zero (e.g. earnings), researchers frequently estimate an average treatment effect (ATE) for a "log-like" transformation that behaves like $\log(Y)$ for large $Y$ but is defined at zero (e.g. $\log(1+Y)$, $\mathrm{arcsinh}(Y)$). We argue that ATEs for log-like transformations should not be interpreted as approximating percentage effects, since unlike a percentage, they depend on the units of the outcome. In…