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右删失结局下最优治疗规则估计量的有限样本表现AI 解读

Patient care may be improved by recommending treatments based on patient characteristics when there is treatment effect heterogeneity. Recently, there has been a great deal of attention focused on the estimation of optimal treatment rules that maximize expected outcomes. However, there has been comparatively less attention given to settings where the outcome is right-censored, especially with regard to the practical use of estimators. In this study, simulations were…

电厂排放控制政策的环境正义影响：二部网络干扰下的异质因果效应估计AI 解读

Emissions generators, such as coal-fired power plants, are key contributors to air pollution and thus environmental policies to reduce their emissions have been proposed. Furthermore, marginalized groups are exposed to disproportionately high levels of this pollution and have heightened susceptibility to its adverse health impacts. As a result, robust evaluations of the heterogeneous impacts of air pollution regulations are key to justifying and designing maximally…

考虑异方差的分层抽样：改进增益建模AI 解读

In many business applications, including online marketing and customer churn prevention, randomized controlled trials (RCT's) are conducted to investigate on the effect of specific treatment (coupon offers, advertisement mailings,...). Such RCT's allow for the estimation of average treatment effects as well as the training of (uplift) models for the heterogeneity of treatment effects between individuals. The problem with these RCT's is that they are costly and this cost…

网络异质性干扰下的个体治疗效应学习AI 解读

Estimates of individual treatment effects from networked observational data are attracting increasing attention these days. One major challenge in network scenarios is the violation of the stable unit treatment value assumption (SUTVA), which assumes that the treatment assignment of a unit does not influence others' outcomes. In network data, due to interference, the outcome of a unit is influenced not only by its treatment (i.e., direct effects) but also by others'…

大量工具变量下的弱识别AI 解读

Linear instrumental variable regressions are widely used to estimate causal effects. Many instruments arise from the use of ``technical'' instruments and more recently from the empirical strategy of ``judge design''. This paper surveys and summarizes ideas from recent literature on estimation and statistical inferences with many instruments for a single endogenous regressor. We discuss how to assess the strength of the instruments and how to conduct weak…

用迁移反事实学习评估电力服务不公平AI 解读

Energy justice is a growing area of interest in interdisciplinary energy research. However, identifying systematic biases in the energy sector remains challenging due to confounding variables, intricate heterogeneity in counterfactual effects, and limited data availability. First, this paper demonstrates how one can evaluate counterfactual unfairness in a power system by analyzing the average causal effect of a specific protected attribute. Subsequently, we use subgroup…

一般处理类型下中介效应的非参数估计AI 解读

To investigate causal mechanisms, causal mediation analysis decomposes the total treatment effect into the natural direct and indirect effects. This paper examines the estimation of the direct and indirect effects in a general treatment effect model, where the treatment can be binary, multi-valued, continuous, or a mixture. We propose generalized weighting estimators with weights estimated by solving an expanding set of equations. Under some sufficient conditions, we show…

SubgroupTE：结合子群识别的治疗效应估计AI 解读

Precise estimation of treatment effects is crucial for evaluating intervention effectiveness. While deep learning models have exhibited promising performance in learning counterfactual representations for treatment effect estimation (TEE), a major limitation in most of these models is that they treat the entire population as a homogeneous group, overlooking the diversity of treatment effects across potential subgroups that have varying treatment effects. This limitation…

结合实验与观察数据进行长期政策评估的夹逼关系AI 解读

Combining short-term experimental data with observational data enables credible long-term policy evaluation. The literature offers two key but non-nested assumptions, namely the latent unconfoundedness (LU; Athey et al., 2020) and equi-confounding bias (ECB; Ghassami et al., 2022) conditions, to correct observational selection. Committing to the wrong assumption leads to biased estimation. To mitigate such risks, we provide a novel bracketing relationship (cf. Angrist and…

带加性与乘性噪声的线性随机微分方程生成元识别AI 解读

In this paper, we present conditions for identifying the generator of a linear stochastic differential equation (SDE) from the distribution of its solution process with a given fixed initial state. These identifiability conditions are crucial in causal inference using linear SDEs as they enable the identification of the post-intervention distributions from its observational distribution. Specifically, we derive a sufficient and necessary condition for identifying the…

当暴露影响子群成员资格：围产期流行病学及其他情境中的因果问题AI 解读

Perinatal epidemiology often aims to evaluate exposures on infant outcomes. When the exposure affects the composition of people who give birth to live infants (e.g., by affecting fertility, behavior, or birth outcomes), this "live birth process" mediates the exposure effect on infant outcomes. Causal estimands previously proposed for this setting include the total exposure effect on composite birth and infant outcomes, controlled direct effects (e.g., enforcing birth), and…

通过条件熵恢复因果分层AI 解读

Causal discovery aims to recover information about an unobserved causal graph from the observable data it generates. Layerings are orderings of the variables which place causes before effects. In this paper, we provide ways to recover layerings of a graph by accessing the data via a conditional entropy oracle, when distributions are discrete. Our algorithms work by repeatedly removing sources or sinks from the graph. Under appropriate assumptions and conditioning, we can…

利用先验知识发现含未观测变量的因果加性模型及其时间序列应用AI 解读

This paper proposes two methods for causal additive models with unobserved variables (CAM-UV). CAM-UV assumes that the causal functions take the form of generalized additive models and that latent confounders are present. First, we propose a method that leverages prior knowledge for efficient causal discovery. Then, we propose an extension of this method for inferring causality in time series data. The original CAM-UV algorithm differs from other existing causal function…

用于因果发现的函数型线性非高斯无环模型AI 解读

In causal discovery, non-Gaussianity has been used to characterize the complete configuration of a Linear Non-Gaussian Acyclic Model (LiNGAM), encompassing both the causal ordering of variables and their respective connection strengths. However, LiNGAM can only deal with the finite-dimensional case. To expand this concept, we extend the notion of variables to encompass vectors and even functions, leading to the Functional Linear Non-Gaussian Acyclic Model (Func-LiNGAM). Our…

重新审视事件研究设计：稳健且有效的估计AI 解读

We develop a framework for difference-in-differences designs with staggered treatment adoption and heterogeneous causal effects. We show that conventional regression-based estimators fail to provide unbiased estimates of relevant estimands absent strong restrictions on treatment-effect homogeneity. We then derive the efficient estimator addressing this challenge, which takes an intuitive "imputation" form when treatment-effect heterogeneity is unrestricted. We characterize…

利用 GWAS 汇总数据估计遗传高斯网络AI 解读

Genetic Gaussian network of multiple phenotypes constructed through the genetic correlation matrix is informative for understanding their biological dependencies. However, its interpretation may be challenging because the estimated genetic correlations are biased due to estimation errors and horizontal pleiotropy inherent in GWAS summary statistics. Here we introduce a novel approach called Estimation of Genetic Graph (EGG), which eliminates the estimation error bias and…

合成组合：组合干预的因果推断框架AI 解读

Consider a setting where there are $N$ heterogeneous units and $p$ interventions. Our goal is to learn unit-specific potential outcomes for any combination of these $p$ interventions, i.e., $N \times 2^p$ causal parameters. Choosing a combination of interventions is a problem that naturally arises in a variety of applications such as factorial design experiments, recommendation engines, combination therapies in medicine, conjoint analysis, etc. Running $N \times 2^p$ experime…

暴露测量误差插补型回归校准的因果协变量选择AI 解读

In this paper, we identify the criteria for the selection of the minimal and most efficient covariate adjustment sets for the regression calibration method developed by Carroll, Rupert and Stefanski (CRS, 1992), used to correct bias due to continuous exposure measurement error. We utilize directed acyclic graphs to illustrate how subject matter knowledge can aid in the selection of such adjustment sets. Valid measurement error correction requires the collection of data on…

随机对照试验中局部平均处理效应的设计型估计与中心极限定理AI 解读

There is a growing literature on design-based methods to estimate average treatment effects for randomized controlled trials (RCTs) using the underpinnings of experiments. In this article, we build on these methods to consider design-based regression estimators for the local average treatment effect (LATE) estimand for RCTs with treatment noncompliance. We prove new finite-population central limit theorems for a range of designs, including blocked and clustered RCTs,…

iSCAN：识别非线性加性噪声模型中的因果机制变化AI 解读

Structural causal models (SCMs) are widely used in various disciplines to represent causal relationships among variables in complex systems. Unfortunately, the underlying causal structure is often unknown, and estimating it from data remains a challenging task. In many situations, however, the end goal is to localize the changes (shifts) in the causal mechanisms between related datasets instead of learning the full causal structure of the individual datasets. Some…

用于因果推断的伪经验似然方法AI 解读

Causal inference problems have remained an important research topic over the past several decades due to their general applicability in assessing a treatment effect in many different real-world settings. In this paper, we propose two inferential procedures on the average treatment effect (ATE) through a two-sample pseudo-empirical likelihood (PEL) approach. The first procedure uses the estimated propensity scores for the formulation of the PEL function, and the resulting…

连续暴露与二元结局匹配观察研究的敏感性分析AI 解读

Matching is one of the most widely used study designs for adjusting for measured confounders in observational studies. However, unmeasured confounding may exist and cannot be removed by matching. Therefore, a sensitivity analysis is typically needed to assess a causal conclusion's sensitivity to unmeasured confounding. Sensitivity analysis frameworks for binary exposures have been well-established for various matching designs and are commonly used in various studies.…

随机对照试验中风险比的不可折叠性与内生选择偏差AI 解读

Background: The hazard ratio of the Cox proportional hazards model is widely used in randomized controlled trials to assess treatment effects. However, two properties of the hazard ratio including the non-collapsibility and built-in selection bias need to be further investigated. Methods: We conduct simulations to differentiate the non-collapsibility effect and built-in selection bias from the difference between the marginal and the conditional hazard ratio. Meanwhile, we…

结合有向无环图的深度学习AI 解读

Social science theories often postulate causal relationships among a set of variables or events. Although directed acyclic graphs (DAGs) are increasingly used to represent these theories, their full potential has not yet been realized in practice. As non-parametric causal models, DAGs require no assumptions about the functional form of the hypothesized relationships. Nevertheless, to simplify the task of empirical evaluation, researchers tend to invoke such assumptions…