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边界断点设计中的操纵检验AI 解读

We propose the first manipulation test designed for boundary discontinuity designs (BDDs) with general boundary shapes. A BDD is a multidimensional extension of the regression discontinuity design (RDD) in which treatment assignment is determined by whether the multidimensional running variable crosses a lower-dimensional boundary set. The test avoids multivariate density estimation and builds on the observation that, in the absence of manipulation, observations near the…

集约边际与广延边际上的处理效应评估AI 解读

This paper provides a solution to the evaluation of treatment effects in selective samples when neither instruments nor parametric assumptions are available. We provide sharp bounds for average treatment effects under a conditional monotonicity assumption for all principal strata, i.e. units characterizing the complete intensive and extensive margins. Most importantly, we allow for a large share of units whose selection is indifferent to treatment, e.g. due to…

高维混杂下纵向数据的异质性分位数处理效应估计（第二版）AI 解读

Causal inference plays a fundamental role in various real-world applications. However, in the motivating non-small cell lung cancer (NSCLC) study, it is challenging to estimate the treatment effect of chemotherapy on circulating tumor DNA (ctDNA). First, the heterogeneous treatment effects vary across patient subgroups defined by baseline characteristics. Second, there exists a broad set of demographic, clinical and molecular variables act as potential confounders. Third,…

存在传播过程的关联群体中的因果推断AI 解读

We address a gap in the literature on causal inference in connected populations: while there is a growing body of work on estimating causal effects in connected populations, little is known about how contagion and other network processes impact causal effects and inference. Contagion and other network processes imply that the outcomes of units affect the outcomes of other units, which enables the effects of interventions to propagate throughout connected populations and…

错时入组与随日历时间变化的效应：因果推断问题AI 解读

Studies with staggered entry, in which individuals enroll at different calendar times, are ubiquitous in medicine and related disciplines. Because these studies usually have a fixed administrative end of follow-up, identification of the estimand of interest relies on assumptions about the right-censoring mechanism. The assumptions are often considered plausible only conditional on covariates, including the time an individual entered the study (E). Yet, censoring assumptions…

测地空间中函数型数据与随机对象的回归不连续设计AI 解读

Regression discontinuity designs (RDDs) are widely used for causal inference in observational studies with cutoff-based treatment assignment, primarily for Euclidean outcomes. We propose the geodesic regression discontinuity design (GRDD), which extends RDDs to complex non-Euclidean outcomes, including networks, compositional data, functional data, and other random objects in geodesic metric spaces. Since algebraic operations are unavailable in such spaces, we define the…

随机对象与函数型数据的测地线合成控制AI 解读

We introduce a geodesic synthetic control method for causal inference with panel outcomes that are random objects in a geodesic metric space. Examples include distributions, compositions, networks, symmetric positive-definite matrices, trees and functional data, among other data types that require a geometry beyond Euclidean vector spaces. The proposed method replaces Euclidean weighted averages by weighted Fréchet means and defines treatment effects as geodesics connecting…

测地线双重差分AI 解读

Difference-in-differences (DID) is a widely used quasi-experimental design for causal inference, traditionally applied to scalar or Euclidean outcomes, while extensions to outcomes residing in non-Euclidean spaces remain limited. Existing methods for such outcomes have primarily focused on univariate distributions, leveraging linear operations in the space of quantile functions, but these approaches cannot be directly extended to outcomes in general metric spaces. In this…

存在网络溢出的交错双重差分：识别与估计AI 解读

This paper studies staggered difference-in-differences designs in which treated and comparison units can be exposed to other units' adoption. Using an exposure mapping specified by the researcher, we define realized and counterfactual exposure states and decompose the total effect into a switching effect of own adoption and a spillover effect under no own adoption. Conditional parallel trends identify the total and switching effects by matching, respectively, the…

簇规模饱和与 g 计算：信息性簇规模下的稳健因果推断AI 解读

Cluster randomized trials (CRTs) can exhibit informative cluster sizes (ICS) where cluster size is associated with outcomes and/or treatment effects. Under ICS, the individual and cluster-average treatment effects (iATE, cATE) can diverge, and the conventional linear mixed-effects model (LMM) and generalized estimating equation (GEE) with an exchangeable working correlation can produce data-dependent weighted contrasts that are not consistent for either estimand. In these…

多暴露与多结局空间回归的谱混杂调整AI 解读

Characterizing social vulnerability is fundamental to disaster response planning. Numerous vulnerability indicators have been developed, but they are typically not validated for their predictive power over the outcomes of interest. As with many environmental health studies where interventions are impractical or unethical, validation of social vulnerability against public health outcomes is observational and relies on spatially-dependent data. Observational studies are…

异质性治疗效应蒸馏：因果推断中的稳定亚组估计AI 解读

Recent methodological developments have introduced new black-box approaches to better estimate heterogeneous treatment effects; however, these methods fall short of providing interpretable characterizations of the underlying individuals who may be most at risk or benefit most from receiving the treatment, thereby limiting their practical utility. In this work, we introduce causal distillation trees (CDT) to estimate interpretable subgroups. CDT allows researchers to fit any…

加权目标量的稳健推断AI 解读

Researchers often conduct inference on weighted estimands, defined as weighted averages of group-level effects. Example settings include event studies with cohort-level effects and experiments with site-level effects. Under heterogeneous effects, different weighting schemes yield estimands with distinct empirical and policy interpretations, leading to ambiguity and disagreement over the choice of weights. I establish bounds on differences between weighted estimands and…

局部爆炸性时间序列的尾部感知密度预测：神经网络方法AI 解读

Mixed causal--noncausal (anticipative) models capture locally explosive dynamics and provide economically meaningful probabilities of continuation and collapse, but forecasting with them remains computationally difficult. We develop a two-stage framework that estimates such an ARMA model and then learns its predictive density using a Mixture Density Network with skewed-t components, tail-aware training weights, and post-hoc calibration. The approach accommodates the heavy…

亚组治疗效应的贝叶斯收缩方法：统一实现与比较AI 解读

Evaluating treatment effect heterogeneity across patient subgroups is a fundamental aspect of clinical trial analysis. These analyses have inherent limitations due to small sample sizes and the substantial number of subgroups investigated. There is a tendency to focus on extreme estimates, which may reflect random variation rather than true effects, potentially leading to spurious clinical conclusions. Statisticians in regulatory agencies and pharmaceutical companies have…

因果—非因果状态空间模型与金融泡沫建模AI 解读

In this paper, we study causal non-causal state space models to model time series characterised by a local explosive increase followed by a sharp decrease such as stock prices. To motivate the use of causal non-causal state space models, we show that the causal non-causal convolution autoregressive model introduced by Gourieroux and Zakoian (2017) can be consistent with the rational expectations stock price model. As in a causal state space model, a central question is how…

通过双重差分学习说服效应AI 解读

We develop a difference-in-differences framework to measure the persuasive impact of informational treatments on behavior in staggered treatment settings. We introduce two causal parameters, the forward and backward average persuasion rates on the treated, which refine the average treatment effect on the treated. The forward rate excludes cases of "preaching to the converted," while the backward rate omits "talking to a brick wall" cases. The backward rate coincides with the…

以 α 期望福利为目标的政策学习AI 解读

This paper proposes an optimal policy that targets the average welfare of the worst-off $α$-fraction of the post-treatment outcome distribution. We refer to this policy as the $α$-Expected Welfare Maximization ($α$-EWM) rule, where $α\in (0,1]$ denotes the size of the subpopulation of interest. The $α$-EWM rule interpolates between the expected welfare ($α=1$) and the Rawlsian welfare ($α\rightarrow 0$). For $α\in (0,1)$, an $α$-EWM rule can be interpreted as a…

协变量数量发散时协变量自适应随机化的理论性质AI 解读

Covariate-adaptive randomization procedures are widely used in clinical trials to improve covariate balance. In modern applications, experimenters often have access to many covariates, motivating the need for a theory of covariate-adaptive randomization procedures with a diverging number of covariates. This paper studies two classes of covariate-adaptive randomization procedures, referred to as imbalance-efficient covariate-adaptive randomization and imbalance-robust…

使用合并逻辑回归的因果生存分析估计方程AI 解读

Background: Pooled logistic regression models are commonly applied in survival analysis. However, the standard implementation can be computationally demanding, which is further exacerbated when using the nonparametric bootstrap for inference. To ease these computational burdens, investigators often coarsen time intervals or assume a parametric functional form for time. These approaches impose restrictive assumptions, which may not always have a well-motivated substantive…

缺乏严格重叠时的分位数处理效应估计AI 解读

We consider the problem of estimating quantile treatment effects without assuming strict overlap, i.e., we do not assume that the propensity score is bounded away from zero. More specifically, we consider an inverse probability weighting (IPW) approach for estimating quantiles in the potential outcomes framework and pay special attention to scenarios where the propensity scores can tend to zero as a regularly varying function. Our approach effectively considers a…

结合协变量调整与次要终点信息提高随机试验精度AI 解读

Background/Aims: Adjustment for prognostic baseline covariates can improve precision in randomized trials. Previous work has shown that jointly modeling primary and secondary endpoints can yield additional precision by borrowing information across endpoints. We investigated whether these approaches can be combined to achieve efficiency gains beyond those obtained through covariate adjustment alone. Methods: We extended a previously proposed one-factor structural equation…

潜在结果有界时的最优实验设计与估计AI 解读

I study the optimal design and analysis of randomized experiments for estimating finite-population average treatment effects when potential outcomes are known to be bounded, as with binary outcomes. Among all assignment mechanisms and a broad class of affine estimators, worst-case mean-squared error (MSE) is minimized by independent random assignment and an unconventional regression of the support-midpoint-centered outcome on the recentered treatment, with no intercept. This…

贝叶斯指标饱和回归AI 解读

Structural break detection has emerged as an important tool for assessing the effects of policies in settings where conventional policy evaluation methods might not be applicable.In this paper, we introduce a unified Bayesian framework for detecting structural breaks with unknown timing and arbitrary sequence in longitudinal data. The proposed setup builds on a indicator-saturated regression design and uses a spike-and-slab prior for selection among indicators. We establish…