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不同非比例风险情形下处理效应评价的统计考量AI 解读

We conducted a systematic comparison of statistical methods used for the analysis of time-to-event outcomes under various proportional and nonproportional hazard (NPH) scenarios. Our study used data from recently published oncology trials to compare the Log-rank test, still by far the most widely used option, against some available alternatives, including the MaxCombo test, the Restricted Mean Survival Time Difference (dRMST) test, the Generalized Gamma Model (GGM) and the…

无法直接分配处理时的自适应实验AI 解读

This paper introduces the \emph{confounded pure exploration transductive linear bandit} (\texttt{CPET-LB}) problem. As a motivating example, often online services cannot directly assign users to specific control or treatment experiences either for business or practical reasons. In these settings, naively comparing treatment and control groups that may result from self-selection can lead to biased estimates of underlying treatment effects. Instead, online services can employ…

利用历史实验选择代理指标AI 解读

In many randomized experiments, the treatment effect of the long-term metric (i.e. the primary outcome of interest) is often difficult or infeasible to measure. Such long-term metrics are often slow to react to changes and sufficiently noisy they are challenging to faithfully estimate in short-horizon experiments. A common alternative is to measure several short-term proxy metrics in the hope they closely track the long-term metric -- so they can be used to effectively guide…

存在测量误差时的协变量平衡AI 解读

In recent years, there is a growing body of causal inference literature focusing on covariate balancing methods. These methods eliminate observed confounding by equalizing covariate moments between the treated and control groups. The validity of covariate balancing relies on an implicit assumption that all covariates are accurately measured, which is frequently violated in observational studies. Nevertheless, the impact of measurement error on covariate balancing is unclear,…

法官工具变量设计中的多维聚类AI 解读

Estimates in judge designs run the risk of being biased due to the many judge identities that are implicitly or explicitly used as instrumental variables. The usual method to analyse judge designs, via a leave-out mean instrument, eliminates this many instrument bias only in case the data are clustered in at most one dimension. What is left out in the mean defines this clustering dimension. How most judge designs cluster their standard errors, however, implies that there are…

高效且全局稳健的因果偏离效应估计AI 解读

Causal excursion effect (CEE) characterizes the effect of an intervention under policies that deviate from the experimental policy. It is widely used to study the effect of time-varying interventions that have the potential to be frequently adaptive, such as those delivered through smartphones. We study the semiparametric efficient estimation of CEE and we derive a semiparametric efficiency bound for CEE with identity or log link functions under working assumptions, in the…

通过稳健估计处理暴露缺失的因果推断AI 解读

How to deal with missing data in observational studies is a common concern for causal inference. When the covariates are missing at random (MAR), multiple approaches have been provided to help solve the issue. However, if the exposure is MAR, few approaches are available and careful adjustments on both missingness and confounding issues are required to ensure a consistent estimate of the true causal effect on the response. In this article, a new inverse probability weighting…

从因果视角评估多模态时间序列预测模型的稳健性AI 解读

AI systems are notorious for their fragility; minor input changes can potentially cause major output swings. When such systems are deployed in critical areas like finance, the consequences of their uncertain behavior could be severe. In this paper, we focus on multi-modal time-series forecasting, where imprecision due to noisy or incorrect data can lead to erroneous predictions, impacting stakeholders such as analysts, investors, and traders. Recently, it has been shown that…

混杂条件下决策策略的预测表现比较AI 解读

Predictive models are often introduced to decision-making tasks under the rationale that they improve performance over an existing decision-making policy. However, it is challenging to compare predictive performance against an existing decision-making policy that is generally under-specified and dependent on unobservable factors. These sources of uncertainty are often addressed in practice by making strong assumptions about the data-generating mechanism. In this work, we…

通过逆概率加权估计赔款准备金：微观链梯法AI 解读

Claim reserving primarily relies on macro-level models, with the Chain-Ladder method being the most widely adopted. These methods were heuristically developed without minimal statistical foundations, relying on oversimplified data assumptions and neglecting policyholder heterogeneity, often resulting in conservative reserve predictions. Micro-level reserving, utilizing stochastic modeling with granular information, can improve predictions but tends to involve less attractive…

处理分配不平衡下双重稳健估计量的校准AI 解读

Machine learning methods, particularly the double machine learning (DML) estimator (Chernozhukov et al., 2018), are increasingly popular for the estimation of the average treatment effect (ATE). However, datasets often exhibit unbalanced treatment assignments where only a few observations are treated, leading to unstable propensity score estimations. We propose a simple extension of the DML estimator which undersamples data for propensity score modeling and calibrates scores…

数据驱动的切换实验：理论权衡与经验贝叶斯设计AI 解读

We study the design and analysis of switchback experiments conducted on a single aggregate unit. The design problem is to partition the continuous time space into intervals and switch treatments between intervals, in order to minimize the estimation error of the treatment effect. We show that the estimation error depends on four factors: carryover effects, periodicity, serially correlated outcomes, and impacts from simultaneous experiments. We derive a rigorous bias-variance…

带阈值识别的生物标志物引导自适应富集生存试验设计AI 解读

Biomarker-guided designs are increasingly used to evaluate personalized treatments based on patients' biomarker status in Phase II and III clinical trials. With adaptive enrichment, these designs can improve the efficiency of evaluating the treatment effect in biomarker-positive patients by increasing their proportion in the randomized trial. While time-to-event outcomes are often used as the primary endpoint to measure treatment effects for a new therapy in severe diseases…

调整潜在同质性以识别治疗社区中的同伴影响AI 解读

We investigate peer role model influence on successful graduation from Therapeutic Communities (TCs) for substance abuse and criminal behavior. We use data from 3 TCs that kept records of exchanges of affirmations among residents and their precise entry and exit dates, allowing us to form peer networks and define a causal effect of interest. The role model effect measures the difference in the expected outcome of a resident (ego) who can observe one of their peers graduate…

可识别异方差噪声模型下的有效因果发现AI 解读

Capturing the underlying structural causal relations represented by Directed Acyclic Graphs (DAGs) has been a fundamental task in various AI disciplines. Causal DAG learning via the continuous optimization framework has recently achieved promising performance in terms of both accuracy and efficiency. However, most methods make strong assumptions of homoscedastic noise, i.e., exogenous noises have equal variances across variables, observations, or even both. The noises in…

用于估计含潜变量因果结构的广义独立噪声条件AI 解读

We investigate the task of learning causal structure in the presence of latent variables, including locating latent variables and determining their quantity, and identifying causal relationships among both latent and observed variables. To this end, we propose a Generalized Independent Noise (GIN) condition for linear non-Gaussian acyclic causal models that incorporate latent variables, which establishes the independence between a linear combination of certain measured…

面板数据中的异质性处理效应AI 解读

We address a core problem in causal inference: estimating heterogeneous treatment effects using panel data with general treatment patterns. Many existing methods either do not utilize the potential underlying structure in panel data or have limitations in the allowable treatment patterns. In this work, we propose and evaluate a new method that first partitions observations into disjoint clusters with similar treatment effects using a regression tree, and then leverages the…

广义结果自适应 Lasso 的 Oracle 性质AI 解读

The generalized outcome-adaptive lasso (GOAL) is a variable selection for high-dimensional causal inference proposed by Baldé et al. [2023, {\em Biometrics} {\bfseries 79(1)}, 514--520]. When the dimension is high, it is now well established that an ideal variable selection method should have the oracle property to ensure the optimal large sample performance. However, the oracle property of GOAL has not been proven. In this paper, we show that the GOAL estimator enjoys the…

使用秩变量回归的因果解释AI 解读

In studies of educational production functions or intergenerational mobility, it is common to transform the key variables into percentile ranks. Yet, it remains unclear what the regression coefficient estimates with ranks of the outcome or the treatment. In this paper, we derive effective causal estimands for a broad class of commonly-used regression methods, including the ordinary least squares (OLS), two-stage least squares (2SLS), difference-in-differences (DiD), and…

未观测异质性引起的时间滞后偏差：随访起点不同的治疗组与对照组比较AI 解读

In comparative effectiveness research, treated and control patients might have a different start of follow-up as treatment is often started later in the disease trajectory. This typically occurs when data from treated and controls are not collected within the same source. Only patients who did not yet experience the event of interest whilst in the control condition end up in the treatment data source. In case of unobserved heterogeneity, these treated patients will have a…

提高平均处理效应跨人群迁移的估计效率AI 解读

We develop flexible, semiparametric estimators of the average treatment effect (ATE) transported to a new population ("target population") that offer potential efficiency gains. Transport may be of value when the ATE may differ across populations. We consider the setting where differences in the ATE are due to differences in the distribution of baseline covariates that modify the treatment effect ("effect modifiers"). First, we propose a collaborative one-step semiparametric…

捆绑商品补贴的学习效应：半参数方法AI 解读

Can temporary subsidies to bundles induce long-run changes in demand due to learning about the quality of one of the constituent goods? This paper provides theoretical support and empirical evidence on this mechanism. Theoretically, we introduce a model where an agent learns about the quality of an innovation through repeated consumption. We then assess the predictions of our theory in a randomised experiment in a ridesharing platform. The experiment subsidised car trips…

DoWhy-GCM：用于图因果模型推断的 DoWhy 扩展AI 解读

We present DoWhy-GCM, an extension of the DoWhy Python library, which leverages graphical causal models. Unlike existing causality libraries, which mainly focus on effect estimation, DoWhy-GCM addresses diverse causal queries, such as identifying the root causes of outliers and distributional changes, attributing causal influences to the data generating process of each node, or diagnosis of causal structures. With DoWhy-GCM, users typically specify cause-effect relations via…

因果性的测度论公理化AI 解读

Causality is a central concept in a wide range of research areas, yet there is still no universally agreed axiomatisation of causality. We view causality both as an extension of probability theory and as a study of \textit{what happens when one intervenes on a system}, and argue in favour of taking Kolmogorov's measure-theoretic axiomatisation of probability as the starting point towards an axiomatisation of causality. To that end, we propose the notion of a \textit{causal…