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Causal Inference with Latent Variables: Recent Advances and Future Prospectives

含潜变量的因果推断:近期进展与未来展望

Causality lays the foundation for the trajectory of our world. Causal inference (CI), which aims to infer intrinsic causal relations among variables of interest, has emerged as a crucial research topic. Nevertheless, the lack of observation of important variables (e.g., confounders, mediators, exogenous variables, etc.) severely compromises the reliability of CI methods. The issue may arise from the inherent difficulty in measuring the variables. Additionally, in…

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Multivariate Bayesian dynamic modeling for causal prediction

用于因果预测的多元贝叶斯动态建模

Bayesian forecasting is developed in multivariate time series analysis for causal inference. Causal evaluation of sequentially observed time series data from control and treated units focuses on the impacts of interventions using contemporaneous outcomes in control units. Methodological developments here concern multivariate dynamic models for time-varying effects across multiple treated units with explicit foci on sequential learning and aggregation of intervention effects.…

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Transporting treatment effects from difference-in-differences studies

将双重差分研究的处理效应迁移至目标总体

Difference-in-differences (DID) is a popular approach to identify the causal effects of treatments and policies in the presence of unmeasured confounding. DID identifies the sample average treatment effect in the treated (SATT). However, a goal of such research is often to inform decision-making in target populations outside the treated sample. Transportability methods have been developed to extend inferences from study samples to external target populations; these methods…

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Active Adaptive Experimental Design for Treatment Effect Estimation with Covariate Choices

可选择协变量的主动自适应处理效应实验设计

This study designs an adaptive experiment for efficiently estimating average treatment effects (ATEs). In each round of our adaptive experiment, an experimenter sequentially samples an experimental unit, assigns a treatment, and observes the corresponding outcome immediately. At the end of the experiment, the experimenter estimates an ATE using the gathered samples. The objective is to estimate the ATE with a smaller asymptotic variance. Existing studies have designed…

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Inference for Nonlinear Endogenous Treatment Effects Accounting for High-Dimensional Covariate Complexity

考虑高维协变量复杂性的非线性内生处理效应推断

Nonlinearity and endogeneity are prevalent challenges in causal analysis using observational data. This paper proposes an inference procedure for a nonlinear and endogenous marginal effect function, defined as the derivative of the nonparametric treatment function, with a primary focus on an additive model that includes high-dimensional covariates. Using the control function approach for identification, we implement a regularized nonparametric estimation to obtain an initial…

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Teleporter Theory: A General and Simple Approach for Modeling Cross-World Counterfactual Causality

传送器理论:跨世界反事实因果建模的一般图示方法

Leveraging the development of structural causal model (SCM), researchers can establish graphical models for exploring the causal mechanisms behind machine learning techniques. As the complexity of machine learning applications rises, single-world interventionism causal analysis encounters theoretical adaptation limitations. Accordingly, cross-world counterfactual approach extends our understanding of causality beyond observed data, enabling hypothetical reasoning about…

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When Graph Neural Network Meets Causality: Opportunities, Methodologies and An Outlook

图神经网络与因果学习:机遇、方法与展望

Graph Neural Networks (GNNs) have emerged as powerful representation learning tools for capturing complex dependencies within diverse graph-structured data. Despite their success in a wide range of graph mining tasks, GNNs have raised serious concerns regarding their trustworthiness, including susceptibility to distribution shift, biases towards certain populations, and lack of explainability. Recently, integrating causal learning techniques into GNNs has sparked numerous…

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Model-Based Inference and Experimental Design for Interference Using Partial Network Data

利用部分网络数据进行干扰效应的模型推断与实验设计

The stable unit treatment value assumption states that the outcome of an individual is not affected by the treatment statuses of others, however in many real world applications, treatments can have an effect on many others beyond the immediately treated. Interference can generically be thought of as mediated through some network structure. In many empirically relevant situations however, complete network data (required to adjust for these spillover effects) are too costly or…

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Spillover Detection for Donor Selection in Synthetic Control Models

合成控制模型中用于供体选择的溢出检测

Synthetic control (SC) models are widely used to estimate causal effects in settings with observational time-series data. To identify the causal effect on a target unit, SC requires the existence of correlated units that are not impacted by the intervention. Given one of these potential donor units, how can we decide whether it is in fact a valid donor - that is, one not subject to spillover effects from the intervention? Such a decision typically requires appealing to…

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Management Decisions in Manufacturing using Causal Machine Learning -- To Rework, or not to Rework?

制造业中的因果机器学习决策:是否返工?

In this paper, we present a data-driven model for estimating optimal rework policies in manufacturing systems. We consider a single production stage within a multistage, lot-based system that allows for optional rework steps. While the rework decision depends on an intermediate state of the lot and system, the final product inspection, and thus the assessment of the actual yield, is delayed until production is complete. Repair steps are applied uniformly to the lot,…

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Statistical Considerations for Evaluating Treatment Effect under Various Non-proportional Hazard Scenarios

不同非比例风险情形下处理效应评价的统计考量

We conducted a systematic comparison of statistical methods used for the analysis of time-to-event outcomes under various proportional and nonproportional hazard (NPH) scenarios. Our study used data from recently published oncology trials to compare the Log-rank test, still by far the most widely used option, against some available alternatives, including the MaxCombo test, the Restricted Mean Survival Time Difference (dRMST) test, the Generalized Gamma Model (GGM) and the…

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Adaptive Experimentation When You Can't Experiment

无法直接分配处理时的自适应实验

This paper introduces the \emph{confounded pure exploration transductive linear bandit} (\texttt{CPET-LB}) problem. As a motivating example, often online services cannot directly assign users to specific control or treatment experiences either for business or practical reasons. In these settings, naively comparing treatment and control groups that may result from self-selection can lead to biased estimates of underlying treatment effects. Instead, online services can employ…

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Choosing a Proxy Metric from Past Experiments

利用历史实验选择代理指标

In many randomized experiments, the treatment effect of the long-term metric (i.e. the primary outcome of interest) is often difficult or infeasible to measure. Such long-term metrics are often slow to react to changes and sufficiently noisy they are challenging to faithfully estimate in short-horizon experiments. A common alternative is to measure several short-term proxy metrics in the hope they closely track the long-term metric -- so they can be used to effectively guide…

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Covariate balancing with measurement error

存在测量误差时的协变量平衡

In recent years, there is a growing body of causal inference literature focusing on covariate balancing methods. These methods eliminate observed confounding by equalizing covariate moments between the treated and control groups. The validity of covariate balancing relies on an implicit assumption that all covariates are accurately measured, which is frequently violated in observational studies. Nevertheless, the impact of measurement error on covariate balancing is unclear,…

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Multidimensional clustering in judge designs

法官工具变量设计中的多维聚类

Estimates in judge designs run the risk of being biased due to the many judge identities that are implicitly or explicitly used as instrumental variables. The usual method to analyse judge designs, via a leave-out mean instrument, eliminates this many instrument bias only in case the data are clustered in at most one dimension. What is left out in the mean defines this clustering dimension. How most judge designs cluster their standard errors, however, implies that there are…

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Efficient and Globally Robust Causal Excursion Effect Estimation

高效且全局稳健的因果偏离效应估计

Causal excursion effect (CEE) characterizes the effect of an intervention under policies that deviate from the experimental policy. It is widely used to study the effect of time-varying interventions that have the potential to be frequently adaptive, such as those delivered through smartphones. We study the semiparametric efficient estimation of CEE and we derive a semiparametric efficiency bound for CEE with identity or log link functions under working assumptions, in the…

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Causal Inference on Missing Exposure via Robust Estimation

通过稳健估计处理暴露缺失的因果推断

How to deal with missing data in observational studies is a common concern for causal inference. When the covariates are missing at random (MAR), multiple approaches have been provided to help solve the issue. However, if the exposure is MAR, few approaches are available and careful adjustments on both missingness and confounding issues are required to ensure a consistent estimate of the true causal effect on the response. In this article, a new inverse probability weighting…

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Rating Multi-Modal Time-Series Forecasting Models (MM-TSFM) for Robustness Through a Causal Lens

从因果视角评估多模态时间序列预测模型的稳健性

AI systems are notorious for their fragility; minor input changes can potentially cause major output swings. When such systems are deployed in critical areas like finance, the consequences of their uncertain behavior could be severe. In this paper, we focus on multi-modal time-series forecasting, where imprecision due to noisy or incorrect data can lead to erroneous predictions, impacting stakeholders such as analysts, investors, and traders. Recently, it has been shown that…

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Predictive Performance Comparison of Decision Policies Under Confounding

混杂条件下决策策略的预测表现比较

Predictive models are often introduced to decision-making tasks under the rationale that they improve performance over an existing decision-making policy. However, it is challenging to compare predictive performance against an existing decision-making policy that is generally under-specified and dependent on unobservable factors. These sources of uncertainty are often addressed in practice by making strong assumptions about the data-generating mechanism. In this work, we…

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Claim Reserving via Inverse Probability Weighting: A Micro-Level Chain-Ladder Method

通过逆概率加权估计赔款准备金:微观链梯法

Claim reserving primarily relies on macro-level models, with the Chain-Ladder method being the most widely adopted. These methods were heuristically developed without minimal statistical foundations, relying on oversimplified data assumptions and neglecting policyholder heterogeneity, often resulting in conservative reserve predictions. Micro-level reserving, utilizing stochastic modeling with granular information, can improve predictions but tends to involve less attractive…

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Calibrating doubly-robust estimators with unbalanced treatment assignment

处理分配不平衡下双重稳健估计量的校准

Machine learning methods, particularly the double machine learning (DML) estimator (Chernozhukov et al., 2018), are increasingly popular for the estimation of the average treatment effect (ATE). However, datasets often exhibit unbalanced treatment assignments where only a few observations are treated, leading to unstable propensity score estimations. We propose a simple extension of the DML estimator which undersamples data for propensity score modeling and calibrates scores…

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Data-Driven Switchback Experiments: Theoretical Tradeoffs and Empirical Bayes Designs

数据驱动的切换实验:理论权衡与经验贝叶斯设计

We study the design and analysis of switchback experiments conducted on a single aggregate unit. The design problem is to partition the continuous time space into intervals and switch treatments between intervals, in order to minimize the estimation error of the treatment effect. We show that the estimation error depends on four factors: carryover effects, periodicity, serially correlated outcomes, and impacts from simultaneous experiments. We derive a rigorous bias-variance…

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Biomarker-Guided Adaptive Enrichment Design with Threshold Detection for Clinical Trials with Time-to-Event Outcome

带阈值识别的生物标志物引导自适应富集生存试验设计

Biomarker-guided designs are increasingly used to evaluate personalized treatments based on patients' biomarker status in Phase II and III clinical trials. With adaptive enrichment, these designs can improve the efficiency of evaluating the treatment effect in biomarker-positive patients by increasing their proportion in the randomized trial. While time-to-event outcomes are often used as the primary endpoint to measure treatment effects for a new therapy in severe diseases…

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Identifying Peer Influence in Therapeutic Communities Adjusting for Latent Homophily

调整潜在同质性以识别治疗社区中的同伴影响

We investigate peer role model influence on successful graduation from Therapeutic Communities (TCs) for substance abuse and criminal behavior. We use data from 3 TCs that kept records of exchanges of affirmations among residents and their precise entry and exit dates, allowing us to form peer networks and define a causal effect of interest. The role model effect measures the difference in the expected outcome of a resident (ego) who can observe one of their peers graduate…

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