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Differential recall bias in estimating treatment effects in observational studies

观察性研究中处理效应估计的差异性回忆偏差

Observational studies are frequently used to estimate the effect of an exposure or treatment on an outcome. To obtain an unbiased estimate of the treatment effect, it is crucial to measure the exposure accurately. A common type of exposure misclassification is recall bias, which occurs in retrospective cohort studies when study subjects may inaccurately recall their past exposure. Particularly challenging is differential recall bias in the context of self-reported binary…

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Statistical and Causal Robustness for Causal Null Hypothesis Tests

因果零假设检验的统计稳健性与因果稳健性

Prior work applying semiparametric theory to causal inference has primarily focused on deriving estimators that exhibit statistical robustness under a prespecified causal model that permits identification of a desired causal parameter. However, a fundamental challenge is correct specification of such a model, which usually involves making untestable assumptions. Evidence factors is an approach to combining hypothesis tests of a common causal null hypothesis under two or more…

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Detecting and Identifying Selection Structure in Sequential Data

序列数据中选择结构的检测与识别

We argue that the selective inclusion of data points based on latent objectives is common in practical situations, such as music sequences. Since this selection process often distorts statistical analysis, previous work primarily views it as a bias to be corrected and proposes various methods to mitigate its effect. However, while controlling this bias is crucial, selection also offers an opportunity to provide a deeper insight into the hidden generation process, as it is a…

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Improving instrumental variable estimators with post-stratification

利用事后分层改善工具变量估计

Experiments studying get-out-the-vote (GOTV) efforts estimate the causal effect of various mobilization efforts on voter turnout. However, there is often substantial noncompliance in these studies. A usual approach is to use an instrumental variable (IV) analysis to estimate impacts for compliers, here being those actually contacted by the investigators. Unfortunately, popular IV estimators can be unstable in studies with a small fraction of compliers. We explore…

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Design-based theory for Lasso adjustment in randomized block experiments and rerandomized experiments

随机区组与再随机化实验中 Lasso 调整的设计型理论

Blocking, a special case of rerandomization, is routinely implemented in the design stage of randomized experiments to balance the baseline covariates. This study proposes a regression adjustment method based on the least absolute shrinkage and selection operator (Lasso) to efficiently estimate the average treatment effect in randomized block experiments with high-dimensional covariates. We derive the asymptotic properties of the proposed estimator and outline the conditions…

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On Counterfactual Interventions in Vector Autoregressive Models

向量自回归模型中的反事实干预

Counterfactual reasoning allows us to explore hypothetical scenarios in order to explain the impacts of our decisions. However, addressing such inquires is impossible without establishing the appropriate mathematical framework. In this work, we introduce the problem of counterfactual reasoning in the context of vector autoregressive (VAR) processes. We also formulate the inference of a causal model as a joint regression task where for inference we use both data with and…

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Improving Finite Sample Performance of Causal Discovery by Exploiting Temporal Structure

利用时间结构改善因果发现的有限样本表现

Methods of causal discovery aim to identify causal structures in a data driven way. Existing algorithms are known to be unstable and sensitive to statistical errors, and are therefore rarely used with biomedical or epidemiological data. We present an algorithm that efficiently exploits temporal structure, so-called tiered background knowledge, for estimating causal structures. Tiered background knowledge is readily available from, e.g., cohort or registry data. When used…

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Stable Differentiable Causal Discovery

稳定的可微分因果发现

Inferring causal relationships as directed acyclic graphs (DAGs) is an important but challenging problem. Differentiable Causal Discovery (DCD) is a promising approach to this problem, framing the search as a continuous optimization. But existing DCD methods are numerically unstable, with poor performance beyond tens of variables. In this paper, we propose Stable Differentiable Causal Discovery (SDCD), a new method that improves previous DCD methods in two ways: (1) It…

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Manipulation Test for Multidimensional RDD

多维回归不连续设计的操纵检验

The causal inference model proposed by Lee (2008) for the regression discontinuity design (RDD) relies on assumptions that imply the continuity of the density of the assignment (running) variable. The test for this implication is commonly referred to as the manipulation test and is regularly reported in applied research to strengthen the design's validity. The multidimensional RDD (MRDD) extends the RDD to contexts where treatment assignment depends on several running…

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Inference in Experiments with Matched Pairs and Imperfect Compliance

配对随机实验与不完全依从下的统计推断

This paper studies inference for the local average treatment effect in randomized controlled trials with imperfect compliance where treatment status is determined according to "matched pairs." By "matched pairs," we mean that units are sampled i.i.d. from the population of interest, paired according to observed, baseline covariates and finally, within each pair, one unit is selected at random for treatment. Under weak assumptions governing the quality of the pairings, we…

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Asymptotic Uncertainty in the Estimation of Frequency Domain Causal Effects for Linear Processes

线性过程频域因果效应估计的渐近不确定性

Structural vector autoregressive (SVAR) processes are commonly used time series models to identify and quantify causal interactions between dynamically interacting processes from observational data. The causal relationships between these processes can be effectively represented by a finite directed process graph - a graph that connects two processes whenever there is a direct delayed or simultaneous effect between them. Recent research has introduced a framework for…

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Causal Responder Detection

因果响应者检测

We introduce the causal responders detection (CARD), a novel method for responder analysis that identifies treated subjects who significantly respond to a treatment. Leveraging recent advances in conformal prediction, CARD employs machine learning techniques to accurately identify responders while controlling the false discovery rate in finite sample sizes. Additionally, we incorporate a propensity score adjustment to mitigate bias arising from non-random treatment…

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Causal Models for Longitudinal and Panel Data: A Survey

纵向与面板数据的因果模型:综述

In this survey we discuss the recent causal panel data literature. This recent literature has focused on credibly estimating causal effects of binary interventions in settings with longitudinal data, emphasizing practical advice for empirical researchers. It pays particular attention to heterogeneity in the causal effects, often in situations where few units are treated and with particular structures on the assignment pattern. The literature has extended earlier work on…

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Copula-Based Estimation of Causal Effects in Multiple Linear and Path Analysis Models

多元线性与路径分析模型中基于 Copula 的因果效应估计

Regression analysis is one of the most popularly used statistical technique which only measures the direct effect of independent variables on dependent variable. Path analysis looks for both direct and indirect effects of independent variables and may overcome several hurdles allied with regression models. It utilizes one or more structural regression equations in the model which are used to estimate the unknown parameters. The aim of this work is to study the path analysis…

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Minimax-Regret Sample Selection in Randomized Experiments

随机实验中的最小最大遗憾样本选择

Randomized controlled trials are often run in settings with many subpopulations that may have differential benefits from the treatment being evaluated. We consider the problem of sample selection, i.e., whom to enroll in a randomized trial, such as to optimize welfare in a heterogeneous population. We formalize this problem within the minimax-regret framework, and derive optimal sample-selection schemes under a variety of conditions. Using data from a COVID-19 vaccine trial,…

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A joint test of unconfoundedness and common trends

无混杂与共同趋势的联合检验

This paper introduces an overidentification test of two alternative assumptions to identify the average treatment effect on the treated in a two-period panel data setting: unconfoundedness and common trends. Under the unconfoundedness assumption, treatment assignment and post-treatment outcomes are independent, conditional on control variables and pre-treatment outcomes, which motivates including pre-treatment outcomes in the set of controls. Conversely, under the common…

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CausalFormer: An Interpretable Transformer for Temporal Causal Discovery

CausalFormer:用于时间因果发现的可解释 Transformer

Temporal causal discovery is a crucial task aimed at uncovering the causal relations within time series data. The latest temporal causal discovery methods usually train deep learning models on prediction tasks to uncover the causality between time series. They capture causal relations by analyzing the parameters of some components of the trained models, e.g., attention weights and convolution weights. However, this is an incomplete mapping process from the model parameters…

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Difference in Differences with Time-Varying Covariates

含时变协变量的双重差分

This paper considers identification and estimation of causal effect parameters from participating in a binary treatment in a difference in differences (DID) setup when the parallel trends assumption holds after conditioning on observed covariates. Relative to existing work in the econometrics literature, we consider the case where the value of covariates can change over time and, potentially, where participating in the treatment can affect the covariates themselves. We…

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Efficient estimation of longitudinal treatment effects using difference-in-differences and machine learning

利用双重差分与机器学习高效估计纵向处理效应

Difference-in-differences is based on a parallel trends assumption, which states that changes over time in average potential outcomes are independent of treatment assignment, possibly conditional on covariates. With time-varying treatments, parallel trends assumptions can identify many types of parameters, but most work has focused on group-time average treatment effects and similar parameters conditional on the treatment trajectory. This paper focuses instead on…

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Sensitivity Analysis of Inverse Probability Weighting Estimators of Causal Effects in Observational Studies with Multivalued Treatments

多值处理观察性研究中因果效应逆概率加权估计的敏感性分析

One of the fundamental challenges in drawing causal inferences from observational studies is that the assumption of no unmeasured confounding is not testable from observed data. Therefore, assessing sensitivity to this assumption's violation is important to obtain valid causal conclusions in observational studies. Although several sensitivity analysis frameworks are available in the casual inference literature, very few of them are applicable to observational studies with…

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Semiparametric Estimation of Treatment Effects in Observational Studies with Heterogeneous Partial Interference

异质性部分干扰下观测研究处理效应的半参数估计

In many observational studies in social science and medicine, subjects or units are connected, and one unit's treatment and attributes may affect another's treatment and outcome, violating the stable unit treatment value assumption (SUTVA) and resulting in interference. To enable feasible estimation and inference, many previous works assume exchangeability of interfering units (neighbors). However, in many applications with distinctive units, interference is heterogeneous…

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Contamination Bias in Linear Regressions

线性回归中的污染偏差

We study regressions with multiple treatments and a set of controls that is flexible enough to purge omitted variable bias. We show that these regressions generally fail to estimate convex averages of heterogeneous treatment effects -- instead, estimates of each treatment's effect are contaminated by non-convex averages of the effects of other treatments. We discuss three estimation approaches that avoid such contamination bias, including the targeting of easiest-to-estimate…

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Interpreting TSLS Estimators in Information Provision Experiments

信息提供实验中两阶段最小二乘估计量的解释

To estimate the causal effects of beliefs on actions, researchers often run information provision experiments. We consider the causal interpretation of two-stage least squares (TSLS) estimators in these experiments. We characterize common TSLS estimators as weighted averages of causal effects, and interpret these weights under general belief updating conditions that nest parametric models from the literature. Our framework accommodates TSLS estimators for both passive and…

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The disruption index suffers from citation inflation and is confounded by shifts in scholarly citation practice

颠覆性指数受到引用膨胀与引用实践变化的混淆

Measuring the rate of innovation in academia and industry is fundamental to monitoring the efficiency and competitiveness of the knowledge economy. To this end, a disruption index (CD) was recently developed and applied to publication and patent citation networks (Wu et al., Nature 2019; Park et al., Nature 2023). Here we show that CD systematically decreases over time due to secular growth in research and patent production, following two distinct mechanisms unrelated to…

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