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ACE：昂贵实验中因果推断的主动学习AI 解读

Experiments are the gold standard for causal inference. In many applications, experimental units can often be recruited or chosen sequentially, and the adaptive execution of such experiments may offer greatly improved inference of causal quantities over non-adaptive approaches, particularly when experiments are expensive. We thus propose a novel active learning method called ACE (Active learning for Causal inference with Expensive experiments), which leverages Gaussian…

预算约束下的 PAC-Bayes 处理分配AI 解读

This paper considers the estimation of treatment assignment rules when the policy maker faces a general budget or resource constraint. Utilizing the PAC-Bayesian framework, we propose new treatment assignment rules that allow for flexible notions of treatment outcome, treatment cost, and a budget constraint. For example, the constraint setting allows for cost-savings, when the costs of non-treatment exceed those of treatment for a subpopulation, to be factored into the…

连接频率学派与贝叶斯变点方法AI 解读

We show that the two-stage minimum description length (MDL) criterion widely used to estimate linear change-point (CP) models corresponds to the marginal likelihood of a Bayesian model with a specific class of prior distributions. This allows results from the frequentist and Bayesian paradigms to be bridged together. Thanks to this link, one can rely on the consistency of the number and locations of the estimated CPs and the computational efficiency of frequentist methods,…

低树秩贝叶斯向量自回归模型AI 解读

Vector autoregression has been widely used for modeling and analysis of multivariate time series data. In high-dimensional settings, model parameter regularization schemes inducing sparsity yield interpretable models and achieved good forecasting performance. However, in many data applications, such as those in neuroscience, the Granger causality graph estimates from existing vector autoregression methods tend to be quite dense and difficult to interpret, unless one…

利用混合人群试验评估生物标志物亚组疗效的贝叶斯元分析AI 解读

During drug development, evidence can emerge to suggest a treatment is more effective in a specific patient subgroup. Whilst early trials may be conducted in biomarker-mixed populations, later trials are more likely to enrol biomarker-positive patients alone, thus leading to trials of the same treatment investigated in different populations. When conducting a meta-analysis, a conservative approach would be to combine only trials conducted in the biomarker-positive subgroup.…

通过倾向得分加权幂先验将外部资料纳入治疗组AI 解读

The incorporation of "real-world data" to supplement the analysis of trials and improve decision-making has spurred the development of statistical techniques to account for introduced confounding. Recently, "hybrid" methods have been developed through which measured confounding is first attenuated via propensity scores and unmeasured confounding is addressed through (Bayesian) dynamic borrowing. Most efforts to date have focused on augmenting control arms with historical…

可微分的多目标因果贝叶斯实验设计AI 解读

We introduce a gradient-based approach for the problem of Bayesian optimal experimental design to learn causal models in a batch setting -- a critical component for causal discovery from finite data where interventions can be costly or risky. Existing methods rely on greedy approximations to construct a batch of experiments while using black-box methods to optimize over a single target-state pair to intervene with. In this work, we completely dispose of the black-box…

状态空间模型的高效变分近似AI 解读

Variational Bayes methods are a potential scalable estimation approach for state space models. However, existing methods are inaccurate or computationally infeasible for many state space models. This paper proposes a variational approximation that is accurate and fast for any model with a closed-form measurement density function and a state transition distribution within the exponential family of distributions. We show that our method can accurately and quickly estimate a…

具有自适应后验集中性质的贝叶斯稀疏因子模型AI 解读

In this paper, we propose a new Bayesian inference method for a high-dimensional sparse factor model that allows both the factor dimensionality and the sparse structure of the loading matrix to be inferred. The novelty is to introduce a certain dependence between the sparsity level and the factor dimensionality, which leads to adaptive posterior concentration while keeping computational tractability. We show that the posterior distribution asymptotically concentrates on the…

bqror：用于有序模型贝叶斯分位数回归的 R 软件包AI 解读

This article describes an R package bqror that estimates Bayesian quantile regression for ordinal models introduced in Rahman (2016). The paper classifies ordinal models into two types and offers computationally efficient, yet simple, Markov chain Monte Carlo (MCMC) algorithms for estimating ordinal quantile regression. The generic ordinal model with 3 or more outcomes (labeled ORI model) is estimated by a combination of Gibbs sampling and Metropolis-Hastings algorithm.…

非参数冲击下贝叶斯 VAR 的快速、变量排序不变推断AI 解读

The shocks which hit macroeconomic models such as Vector Autoregressions (VARs) have the potential to be non-Gaussian, exhibiting asymmetries and fat tails. This consideration motivates the VAR developed in this paper which uses a Dirichlet process mixture (DPM) to model the shocks. However, we do not follow the obvious strategy of simply modeling the VAR errors with a DPM since this would lead to computationally infeasible Bayesian inference in larger VARs and potentially a…

基于图像的处理效应异质性分析AI 解读

Randomized controlled trials (RCTs) are considered the gold standard for estimating the average treatment effect (ATE) of interventions. One use of RCTs is to study the causes of global poverty -- a subject explicitly cited in the 2019 Nobel Memorial Prize awarded to Duflo, Banerjee, and Kremer "for their experimental approach to alleviating global poverty." Because the ATE is a population summary, anti-poverty experiments often seek to unpack the effect variation around the…

椭圆分布多元随机效应模型的客观贝叶斯推断与 Gibbs 采样AI 解读

In this paper, we present the Bayesian inference procedures for the parameters of the multivariate random effects model derived under the assumption of an elliptically contoured distribution when the Berger and Bernardo reference and the Jeffreys priors are assigned to the model parameters. We develop a new numerical algorithm for drawing samples from the posterior distribution, which is based on the hybrid Gibbs sampler. The new approach is compared to the two…

利用贝叶斯非参数依赖混合模型估计限制平均生存时间AI 解读

Restricted mean survival time (RMST) is an intuitive summary statistic for time-to-event random variables, and can be used for measuring treatment effects. Compared to hazard ratio, its estimation procedure is robust against the non-proportional hazards assumption. We propose nonparametric Bayeisan (BNP) estimators for RMST using a dependent stick-breaking process prior mixture model that adjusts for mixed-type covariates. The proposed Bayesian estimators can yield both…

动态高斯图模型的变点检测：新冠疫情期间美国股市的依赖变化AI 解读

Reliable estimates of volatility and correlation are fundamental in economics and finance for understanding the impact of macroeconomics events on the market and guiding future investments and policies. Dependence across financial returns is likely to be subject to sudden structural changes, especially in correspondence with major global events, such as the COVID-19 pandemic. In this work, we are interested in capturing abrupt changes over time in the dependence across US…

博弈中的稳定结果与信息：一个实证框架AI 解读

Empirically, many strategic settings are characterized by stable outcomes in which players' decisions are publicly observed, yet no player takes the opportunity to deviate. To analyze such situations in the presence of incomplete information, we build an empirical framework by introducing a novel solution concept that we call Bayes stable equilibrium. Our framework allows the researcher to be agnostic about players' information and the equilibrium selection rule. The Bayes…

通过变分因果推理提升目标条件强化学习的泛化能力AI 解读

As a pivotal component to attaining generalizable solutions in human intelligence, reasoning provides great potential for reinforcement learning (RL) agents' generalization towards varied goals by summarizing part-to-whole arguments and discovering cause-and-effect relations. However, how to discover and represent causalities remains a huge gap that hinders the development of causal RL. In this paper, we augment Goal-Conditioned RL (GCRL) with Causal Graph (CG), a structure…

多国宏观经济风险监测AI 解读

We propose a multicountry quantile factor augmeneted vector autoregression (QFAVAR) to model heterogeneities both across countries and across characteristics of the distributions of macroeconomic time series. The presence of quantile factors allows for summarizing these two heterogeneities in a parsimonious way. We develop two algorithms for posterior inference that feature varying level of trade-off between estimation precision and computational speed. Using monthly data…

缺失数据模型的贝叶斯敏感性分析AI 解读

In causal inference, sensitivity analysis is important to assess the robustness of study conclusions to key assumptions. We perform sensitivity analysis of the assumption that missing outcomes are missing completely at random. We follow a Bayesian approach, which is nonparametric for the outcome distribution and can be combined with an informative prior on the sensitivity parameter. We give insight in the posterior and provide theoretical guarantees in the form of…

弱识别下 GMM 的不可容许性AI 解读

We consider estimation in moment condition models and show that under any bound on identification strength, asymptotically admissible (i.e. undominated) estimators in a wide class of estimation problems must be uniformly continuous in the sample moment function. GMM estimators are in general discontinuous in the sample moments, and are thus inadmissible. We show, by contrast, that bagged, or bootstrap aggregated, GMM estimators as well as quasi-Bayes posterior means have…

工作障碍功能评估量表的自编码稀疏贝叶斯 IRT 内因子分解、校准与摊销推断AI 解读

The Work Disability Functional Assessment Battery (WD-FAB) is a multidimensional item response theory (IRT) instrument designed for assessing work-related mental and physical function based on responses to an item bank. In prior iterations it was developed using traditional means -- linear factorization and null hypothesis statistical testing for item partitioning/selection, and finally, posthoc calibration of disjoint unidimensional IRT models. As a result, the WD-FAB, like…

存在处理后混杂变量时因果中介分析的贝叶斯非参数方法AI 解读

We propose a new Bayesian non-parametric (BNP) method for estimating the causal effects of mediation in the presence of a post-treatment confounder. We specify an enriched Dirichlet process mixture (EDPM) to model the joint distribution of the observed data (outcome, mediator, post-treatment confounders, treatment, and baseline confounders). The proposed BNP model allows more confounder-based clusters than clusters for the outcome and mediator. For identifiability, we use…

用于构建临床试验合成对照组的贝叶斯非参数共同原子回归AI 解读

The availability of electronic health records (EHR) has opened opportunities to supplement increasingly expensive and difficult to carry out randomized controlled trials (RCT) with evidence from readily available real world data. In this paper, we use EHR data to construct synthetic control arms for treatment-only single arm trials. We propose a novel nonparametric Bayesian common atoms mixture model that allows us to find equivalent population strata in the EHR and the…

贝叶斯预测决策综合AI 解读

Decision-guided perspectives on model uncertainty expand traditional statistical thinking about managing, comparing and combining inferences from sets of models. Bayesian predictive decision synthesis (BPDS) advances conceptual and theoretical foundations, and defines new methodology that explicitly integrates decision-analytic outcomes into the evaluation, comparison and potential combination of candidate models. BPDS extends recent theoretical and practical advances based…