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早期肿瘤试验混合对照方法评估：基于MORPHEUS-UC的模拟研究AI 解读

Phase Ib/II oncology trials, despite their small sample sizes, aim to provide information for optimal internal company decision-making concerning novel drug development. Hybrid controls (a combination of the current control arm and controls from one or more sources of historical trial data [HTD]) can be used to increase the statistical precision. Here we assess combining two sources of Roche HTD to construct a hybrid control in targeted therapy for decision-making via an…

无预设空间权重限制的面板空间自回归模型快速两阶段变分贝叶斯估计AI 解读

This paper proposes a fast two-stage variational Bayesian (VB) algorithm to estimate unrestricted panel spatial autoregressive models. Using Dirichlet-Laplace priors, we are able to uncover the spatial relationships between cross-sectional units without imposing any a priori restrictions. Monte Carlo experiments show that our approach works well for both long and short panels. We are also the first in the literature to develop VB methods to estimate large covariance matrices…

不依赖评分等价性的基于排序的结构学习AI 解读

We propose an empirical Bayes formulation of the structure learning problem, where the prior specification assumes that all node variables have the same error variance, an assumption known to ensure the identifiability of the underlying causal directed acyclic graph (DAG). To facilitate efficient posterior computation, we approximate the posterior probability of each ordering by that of a best DAG model, which naturally leads to an order-based Markov chain Monte Carlo (MCMC)…

因果模型中最优干预设计的主动学习AI 解读

Sequential experimental design to discover interventions that achieve a desired outcome is a key problem in various domains including science, engineering and public policy. When the space of possible interventions is large, making an exhaustive search infeasible, experimental design strategies are needed. In this context, encoding the causal relationships between the variables, and thus the effect of interventions on the system, is critical for identifying desirable…

结合机器学习、混合 Logit 与非线性规划优化 B2B 产品报价AI 解读

In B2B markets, value-based pricing and selling has become an important alternative to discounting. This study outlines a modeling method that uses customer data (product offers made to each current or potential customer, features, discounts, and customer purchase decisions) to estimate a mixed logit choice model. The model is estimated via hierarchical Bayes and machine learning, delivering customer-level parameter estimates. Customer-level estimates are input into a…

集群生存数据的新方法：处理效应异质性估计与变量选择AI 解读

We recently developed a new method riAFT-BART to draw causal inferences about population treatment effect on patient survival from clustered and censored survival data while accounting for the multilevel data structure. The practical utility of this method goes beyond the estimation of population average treatment effect. In this work, we exposit how riAFT-BART can be used to solve two important statistical questions with clustered survival data: estimating the treatment…

可观测处理异质性下用于优效决策的贝叶斯多层多元逻辑回归AI 解读

In medical, social, and behavioral research we often encounter datasets with a multilevel structure and multiple correlated dependent variables. These data are frequently collected from a study population that distinguishes several subpopulations with different (i.e., heterogeneous) effects of an intervention. Despite the frequent occurrence of such data, methods to analyze them are less common and researchers often resort to either ignoring the multilevel and/or…

尊重随机占优的统计决策理论AI 解读

The statistical decision theory pioneered by Wald (1950) has used state-dependent mean loss (risk) to measure the performance of statistical decision functions across potential samples. We think it evident that evaluation of performance should respect stochastic dominance, but we do not see a compelling reason to focus exclusively on mean loss. We think it instructive to also measure performance by other functionals that respect stochastic dominance, such as quantiles of the…

校正幸存者偏差的可解释异质性治疗效应：出院后干预与再入院预防AI 解读

We used survival analysis to quantify the impact of postdischarge evaluation and management (E/M) services in preventing hospital readmission or death. Our approach avoids a specific pitfall of applying machine learning to this problem, which is an inflated estimate of the effect of interventions, due to survivors bias -- where the magnitude of inflation may be conditional on heterogeneous confounders in the population. This bias arises simply because in order to receive an…

动态离散选择模型的半参数贝叶斯估计AI 解读

We propose a tractable semiparametric estimation method for structural dynamic discrete choice models. The distribution of additive utility shocks in the proposed framework is modeled by location-scale mixtures of extreme value distributions with varying numbers of mixture components. Our approach exploits the analytical tractability of extreme value distributions in the multinomial choice settings and the flexibility of the location-scale mixtures. We implement the Bayesian…

银行、金融与保险中的因果推断综述AI 解读

Causal Inference plays an significant role in explaining the decisions taken by statistical models and artificial intelligence models. Of late, this field started attracting the attention of researchers and practitioners alike. This paper presents a comprehensive survey of 37 papers published during 1992-2023 and concerning the application of causal inference to banking, finance, and insurance. The papers are categorized according to the following families of domains: (i)…

面向后续处理效应估计的贝叶斯因果发现方法评测AI 解读

The practical utility of causality in decision-making is widespread and brought about by the intertwining of causal discovery and causal inference. Nevertheless, a notable gap exists in the evaluation of causal discovery methods, where insufficient emphasis is placed on downstream inference. To address this gap, we evaluate seven established baseline causal discovery methods including a newly proposed method based on GFlowNets, on the downstream task of treatment effect…

经济与金融中的贝叶斯预测：现代综述AI 解读

The Bayesian statistical paradigm provides a principled and coherent approach to probabilistic forecasting. Uncertainty about all unknowns that characterize any forecasting problem -- model, parameters, latent states -- is able to be quantified explicitly, and factored into the forecast distribution via the process of integration or averaging. Allied with the elegance of the method, Bayesian forecasting is now underpinned by the burgeoning field of Bayesian computation,…

自动推断聚类数与因子数的动态有限因子分析混合模型AI 解读

Mixtures of factor analysers (MFA) models represent a popular tool for finding structure in data, particularly high-dimensional data. While in most applications the number of clusters, and especially the number of latent factors within clusters, is mostly fixed in advance, in the recent literature models with automatic inference on both the number of clusters and latent factors have been introduced. The automatic inference is usually done by assigning a nonparametric prior…

用于时间序列结构发现的序贯蒙特卡洛学习AI 解读

This paper presents a new approach to automatically discovering accurate models of complex time series data. Working within a Bayesian nonparametric prior over a symbolic space of Gaussian process time series models, we present a novel structure learning algorithm that integrates sequential Monte Carlo (SMC) and involutive MCMC for highly effective posterior inference. Our method can be used both in "online" settings, where new data is incorporated sequentially in time, and…

无转移支付的多对一双边匹配：识别与估计AI 解读

In a setting of many-to-one two-sided matching with non-transferable utilities, e.g., college admissions, we study conditions under which preferences of both sides are identified with data on one single market. Regardless of whether the market is centralized or decentralized, assuming that the observed matching is stable, we show nonparametric identification of preferences of both sides under certain exclusion restrictions. To take our results to the data, we use Monte Carlo…

大型贝叶斯向量自回归的变分推断AI 解读

We propose a novel variational Bayes approach to estimate high-dimensional vector autoregression (VAR) models with hierarchical shrinkage priors. Our approach does not rely on a conventional structural VAR representation of the parameter space for posterior inference. Instead, we elicit hierarchical shrinkage priors directly on the matrix of regression coefficients so that (1) the prior structure directly maps into posterior inference on the reduced-form transition matrix,…

类别变量图模型的联合结构学习与因果效应估计AI 解读

We consider a a collection of categorical random variables. Of special interest is the causal effect on an outcome variable following an intervention on another variable. Conditionally on a Directed Acyclic Graph (DAG), we assume that the joint law of the random variables can be factorized according to the DAG, where each term is a categorical distribution for the node-variable given a configuration of its parents. The graph is equipped with a causal interpretation through…

评估政策对心理福祉影响的贝叶斯中断时间序列：英格兰福利改革应用AI 解读

Factors contributing to social inequalities are also associated with negative mental health outcomes leading to disparities in mental well-being. We propose a Bayesian hierarchical model which can evaluate the impact of policies on population well-being, accounting for spatial/temporal dependencies. Building on an interrupted time series framework, our approach can evaluate how different profiles of individuals are affected in different ways, whilst accounting for their…

高维潜变量模型的混合无校正 Langevin 方法AI 解读

The exact estimation of latent variable models with big data is known to be challenging. The latents have to be integrated out numerically, and the dimension of the latent variables increases with the sample size. This paper develops a novel approximate Bayesian method based on the Langevin diffusion process. The method employs the Fisher identity to integrate out the latent variables, which makes it accurate and computationally feasible when applied to big data. In contrast…

多元时间序列贝叶斯谱分析的非参数修正似然AI 解读

This paper presents a novel approach to Bayesian nonparametric spectral analysis of stationary multivariate time series. Starting with a parametric vector-autoregressive model, the parametric likelihood is nonparametrically adjusted in the frequency domain to account for potential deviations from parametric assumptions. We show mutual contiguity of the nonparametrically corrected likelihood, the multivariate Whittle likelihood approximation and the exact likelihood for…

歧视评估成绩单AI 解读

We develop an Empirical Bayes grading scheme that balances the informativeness of the assigned grades against the expected frequency of ranking errors. Applying the method to a massive correspondence experiment, we grade the racial biases of 97 U.S. employers. A four-grade ranking limits the chances that a randomly selected pair of firms is mis-ranked to 5% while explaining nearly half of the variation in firms' racial contact gaps. The grades are presented alongside…

纵向数据极端值的统计建模框架及精英游泳应用AI 解读

We develop methods, based on extreme value theory, for analysing observations in the tails of longitudinal data, i.e., a data set consisting of a large number of short time series, which are typically irregularly and non-simultaneously sampled, yet have some commonality in the structure of each series and exhibit independence between time series. Extreme value theory has not been considered previously for the unique features of longitudinal data. Across time series the data…

半参数后验校正AI 解读

We present a new approach to semiparametric inference using corrected posterior distributions. The method allows us to leverage the adaptivity, regularization and predictive power of nonparametric Bayesian procedures to estimate low-dimensional functionals of interest without being restricted by the holistic Bayesian formalism. Starting from a conventional nonparametric posterior, we target the functional of interest by transforming the entire distribution with a Bayesian…