Penalized Cox Regression with Graph-Structured Distribution-Valued Predictors
图结构分布值预测变量的惩罚Cox回归
We propose the Graph-Fused Distributional Cox Model (GFDCM), a penalized survival analysis framework for distribution-valued predictors organized on a known graph. Modern neuroimaging studies collect high-dimensional voxel-level measurements across multiple regions of interest (ROIs) with rich spatial dependency structures. Rather than reducing these to scalar summaries, GFDCM models the full distribution of voxel intensities within each ROI, retaining region-specific…