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Identifying the desert decision rule to assess and achieve fairness

识别应得决策规则以评估与实现公平

We study fairness in decision-making when the data may encode systematic bias. Existing approaches typically impose fairness constraints while predicting the observed decision, which may itself be unfair. We propose a novel framework for characterising and addressing fairness issues by introducing the notion of desert decision, a latent variable representing the decision an individual rightfully deserves based on their actions, efforts, or abilities. This formulation shifts…

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Identifying Genetic Variants for Obesity: A Knowledge Integration Quantile Regression (KIQR) Approach for Ultra-High-Dimensional Data

面向肥胖遗传变异的超高维数据知识整合分位数回归方法

Obesity is widely recognized as a serious and pervasive health concern. We study obesity through body mass index (BMI), which is known to be highly heritable, and identify important genetic risk factors for BMI from hundreds of thousands of single nucleotide polymorphisms (SNPs) in the Framingham Study data. Several challenges arise when using traditional genome-wide association studies (GWAS): (1) They suffer from a low power due to a combination of a limited number of…

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Omitted-Variable Sensitivity Analysis for Generalizing Randomized Trials

随机试验结果推广的遗漏变量敏感性分析

Randomized controlled trials (RCTs) yield internally valid causal effect estimates, but generalizing these results to target populations with different characteristics requires an untestable selection ignorability assumption: conditional on observed covariates, trial participation must be independent of potential outcomes. This assumption fails when unobserved effect modifiers are distributed differently between trial and target populations. We develop a sensitivity analysis…

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Identifying Causal Effects Using Instrumental Variables from the Auxiliary Dataset

利用辅助数据集中的工具变量识别因果效应

Instrumental variable approaches have gained popularity for estimating causal effects in the presence of unmeasured confounders. However, the availability of instrumental variables in the primary dataset is often challenged due to stringent and untestable assumptions. This paper presents a novel method to identify and estimate causal effects by utilizing instrumental variables from the auxiliary dataset, incorporating a structural equation model, even in scenarios with…

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Identifiability of causal effects with non-Gaussianity and auxiliary covariates

利用非高斯性与辅助协变量识别因果效应

Assessing causal effects in the presence of unmeasured confounding is challenging. Although auxiliary variables, such as instrumental variables, are commonly used to identify causal effects, they are often unavailable in practice due to stringent and untestable conditions. To address this issue, previous researches have utilized linear structural equation models to show that the causal effect is identifiable when noise variables of the treatment and outcome are both…

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Combining BART and Principal Stratification to estimate the effect of intermediate on primary outcomes with application to estimating the effect of family planning on employment in sub-Saharan Africa

结合 BART 与主分层估计中间变量效应:撒哈拉以南非洲计划生育与就业

There is interest in learning about the causal effect of family planning (FP) on empowerment related outcomes. Experimental data related to this question are available from trials in which FP programs increase access to FP. While program assignment is unconfounded, FP uptake and subsequent empowerment may share common causes. We use principal stratification to estimate the causal effect of an intermediate FP outcome on a primary outcome of interest, among women affected by a…

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Combining BART and Principal Stratification to estimate the effect of intermediate variables on primary outcomes with application to estimating the effect of family planning on employment in Nigeria and Senegal

结合 BART 与主分层估计避孕使用对就业的影响:尼日利亚与塞内加尔

There is interest in learning about the causal effects of modern contraceptive use on empowerment outcomes. Data on this question often come from family planning (FP) programs that increase access to FP and facilitate contraceptive use among some women, rather than directly assigning use. Women whose contraceptive behavior changes because of these programs ("compliers") may differ from target populations in ways that alter the consequences of contraceptive use for…

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Mediation analysis with unmeasured confounding between parallel mediators and outcome

平行中介与结果之间存在未测混杂的中介分析

Mediation analysis extending beyond single mediators has gained significant attention in recent years. However, related methods often assume the absence of unmeasured mediator-outcome confounding. To address this, we develop a mediation analysis framework that accounts for such confounding within a linear structural equation model with parallel mediators. Specifically, we introduce a pseudo proxy variable to capture unmeasured confounding, allowing us to identify causal…

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A Nonparametric Framework for Universal Difference-in-Differences

通用双重差分的非参数框架

Difference-in-differences (DiD) is a popular approach to evaluate treatment effects in settings where both pre- and post-treatment measurements of the outcome are available. Despite its popularity, existing methods face important limitations. Specifically, they either: (i) only apply to continuous outcomes and the average treatment effect on the treated; (ii) are sensitive to the transformation of the outcome; (iii) rely on a no unmeasured confounding assumption given…

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Retrospective Counterfactual Prediction by Conditioning on the Factual Outcome: A Cross-World Approach

以事实结果为条件的回溯反事实预测:跨世界方法

Retrospective causal questions ask what would have happened to an observed individual had they received a different treatment. We study the problem of estimating $μ(x,y)=\mathbb{E}[Y(1)\mid X=x,Y(0)=y]$, the expected counterfactual outcome for an individual with covariates $x$ and observed outcome $y$, and constructing valid prediction intervals under the Neyman-Rubin superpopulation model. This quantity is generally not identified without additional assumptions. To link the…

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Cross-World Assumption and Refining Prediction Intervals for Individual Treatment Effects

跨世界假设与个体处理效应预测区间的细化

While average treatment effects (ATE) and conditional average treatment effects (CATE) provide valuable population- and subgroup-level summaries, they fail to capture uncertainty at the individual level. For high-stakes decision-making, individual treatment effect (ITE) estimates must be accompanied by valid prediction intervals that reflect heterogeneity and unit-specific uncertainty. However, the fundamental unidentifiability of ITEs limits the ability to derive precise…

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Enhanced inference for distributions and quantiles of individual treatment effects in various experiments

多类实验中个体处理效应分布与分位数的改进推断

Understanding treatment effect heterogeneity has become increasingly important in many fields. In this paper we study distributions and quantiles of individual treatment effects to provide a more comprehensive and robust understanding of treatment effects beyond usual averages, despite they are more challenging to infer due to nonidentifiability from observed data. Recent randomization-based approaches offer finite-sample valid inference for treatment effect distributions…

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Maximin Learning of Individualized Treatment Effect on Multi-Domain Outcomes

多领域结局下个体化处理效应的最大最小学习

Precision mental health requires treatment decisions that account for heterogeneous symptoms reflecting multiple clinical domains. However, existing methods for estimating individualized treatment effects (ITE) rely on a single summary outcome or a specific set of observed symptoms or measures, which are sensitive to symptom selection and limit generalizability to unmeasured yet clinically relevant domains. We propose DRIFT, a new maximin framework for estimating robust ITEs…

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Non-robustness of diffusion estimates on networks with measurement error

测量误差下网络扩散估计的非稳健性

Network diffusion models are used to study disease transmission, information spread, technology adoption, and other socio-economic processes. We show that estimates of these diffusions are highly non-robust to mismeasurement. First, even when the network is measured perfectly, small and local mismeasurement in the initial seed generates a large shift in the locations of the expected diffusion. Second, if instead the initial seed is known, even a vanishingly small share of…

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Bayesian analysis of the causal reference-based model for missing data in clinical trials, accommodating partially observed post-intercurrent event data

纳入部分伴发事件后观测的临床试验因果参考模型贝叶斯分析

When treatment policy estimands are of interest, clinical trials often attempt to collect patient data after intercurrent events (ICEs), although such data are often limited. Retrieved dropout imputation methods, which use pre-ICE and available post-ICE data to impute missing post-ICE outcomes, are commonly applied but often yield treatment effect estimates with large standard errors (SEs) and may encounter convergence issues when post-ICE data are sparse. Reference-based…

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A framework for joint assessment of a terminal event and a score existing only in the absence of the terminal event

终末事件与仅在事件未发生时存在的评分之联合评估框架

Analysis of data from randomized controlled trials in vulnerable populations requires special attention when assessing treatment effect by a score measuring, e.g., disease stage or activity together with onset of prevalent terminal events. In reality, it is impossible to disentangle a disease score from the terminal event, since the score is not clinically meaningful after this event. In this work, we propose to assess treatment interventions simultaneously on the terminal…

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A Calibration Framework for Inference with Partially Observed Data

部分观测数据推断的校准框架

Missing data is an universal problem in statistics. We develop a unified framework for estimating parameters defined by general estimating equations under a missing-at-random (MAR) mechanism, based on generalized entropy calibration weighting. We construct weights by minimizing a convex entropy subject to (i) balancing constraints on a data-adaptive calibration function, estimated using flexible machine-learning predictors with cross-fitting, and (ii) a debiasing constraint…

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Targeted learning of heterogeneous treatment effect curves for right censored or left truncated time-to-event data

右删失或左截断生存数据中异质处理效应曲线的目标学习

In recent years, there has been growing interest in causal machine learning estimators for quantifying subject-specific effects of a binary treatment on time-to-event outcomes. Estimation approaches have been proposed which attenuate the inherent regularisation bias in machine learning predictions, with each of these estimators addressing measured confounding, right censoring, and in some cases, left truncation. However, the existing approaches are found to exhibit…

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The relative value of interventional and observational samples in Bayesian Causal Linear Gaussian Models

贝叶斯线性高斯因果模型中干预与观测样本的相对价值

We investigate the asymptotic properties of Bayesian bivariate causal discovery for Gaussian Linear Structural Equation Models (SEMs) with heteroscedastic noise. We demonstrate that with purely observational data, the posterior distribution over the models fails to consistently identify the true causal structure - a consequence of the fundamental non-identifiability within the Markov Equivalence Class. Specifically, if the true generating mechanism corresponds to a connected…

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Complete Causal Identification from Ancestral Graphs under Selection Bias

选择偏差下祖先图的完备因果识别

Many causal discovery algorithms, including the celebrated FCI algorithm, output a Partial Ancestral Graph (PAG). PAGs serve as an abstract graphical representation of the underlying causal structure, modeled by directed acyclic graphs with latent and selection variables. This paper develops a characterization of the set of extended-type conditional independence relations that are invariant across all causal models represented by a PAG. This theory allows us to formulate a…

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Randomization Inference For the Always-Reporter Average Treatment Effect

始终报告者平均处理效应的随机化推断

This article studies randomization inference for treatment effects in randomized controlled trials with attrition, where outcomes are observed for only a subset of units. We assume monotonicity in reporting behavior as in \cite{lee2009training} and focus on the average treatment effect for always-reporters (AR-ATE), defined as units whose outcomes are observed under both treatment and control. Because always-reporter status is only partially revealed by observed assignment…

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Randomization Inference in Two-Sided Market Experiments

双边市场实验中的随机化推断

Randomized experiments are increasingly employed in two-sided markets, such as buyer--seller platforms, to evaluate the effects of marketplace interventions. These experiments must reflect the underlying two-sided market structure in their design and can therefore be challenging to analyze. In this paper, we develop a randomization inference framework for outcomes from two-sided experiments, with a focus on testing and inference for two-sided spillover effects. Our approach…

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Regularized Regression by Composition: Identifiability, Structured Penalization, and Statistical Guarantees for Multi-Flow Distributional Models

基于复合的正则化回归:多流分布模型的可识别性、结构化惩罚与统计保证

Regression by composition provides a flexible framework for constructing conditional distributions through sequential group actions. However, when multiple flows act on the same distribution, the model becomes non-identifiable, leading to flat likelihood regions and unstable estimates. We introduce a structured regularization framework that resolves this issue by assigning flow-specific penalties. The resulting estimator is defined as a penalized maximum likelihood problem…

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Causal Network Discovery from Interventional Count Data with Latent Linear DAGs

潜在线性 DAG 下干预计数数据的因果网络发现

The increasing availability of interventional data offers new opportunities for causal discovery, with gene perturbation studies providing a prominent example. Such data are typically count-valued and subject to substantial measurement error arising from technical variability and latent state heterogeneity. Motivated by these challenges, we study identification and estimation in latent linear structural causal models for interventional count data. We propose a latent linear…

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