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Synthetic Control under Out-of-Span Common Shocks: Diagnosis, Exposure Balance and Correction

跨度之外共同冲击下的合成控制:诊断、暴露平衡与修正

Synthetic control relies on pre-treatment fit to balance the unobserved factors that drive untreated outcomes. The argument fails when an observed common shock, such as a commodity price, moves with the latent factors before treatment and departs from them afterwards and pre-treatment fit then says almost nothing about the synthetic unit's exposure to the shock. I derive a period-specific bound that links the post-treatment bias of any weighting estimator to pre-treatment…

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Direct Learning of Treatment-Benefit Rankings for Restricted Mean Survival Time in Randomized Trials with Censoring

删失随机试验中限制平均生存时间处理获益排序的直接学习

In precision medicine, treatment decisions often depend more on identifying which patients are most likely to benefit from treatment than on accurately estimating benefit for every patient. However, existing methods estimate patient-specific treatment effects and derive patient rankings as a secondary step. We propose a direct ranking approach for conditional RMST treatment benefit in randomized trials with right-censored outcomes. We first construct a censoring-adjusted…

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Surrogate-powered Causal Inference with Censored Outcomes

利用辅助事件信息进行删失结局的因果推断

Clinical trials with survival endpoints lose information when participants are censored before death is observed. We develop target-preserving estimators that use posttreatment disease history, such as recurrence or progression, to recover information lost to censoring for marginal survival and restricted mean survival effects. The difficulty is that the intermediate event is downstream of treatment: naive adjustment can change the causal estimand, and the useful information…

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What does two-sample Mendelian randomization estimate when the exposure-outcome relationship is nonlinear?

暴露与结局关系非线性时,两样本孟德尔随机化估计什么?

Two-sample Mendelian randomization with summary statistics has become a popular MR design in Epidemiology. Its ratio estimate has an average causal effect interpretation only under strong untestable assumptions including linearity. We derive what the per-variant ratio, and the pooled and robust estimators built from it, estimate when a continuous exposure has a nonlinear effect, under two conditions on how genetic variation and unmeasured factors shape exposure: no…

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Minimax estimation of the expected conditional covariance under bounds on the covariate density

协变量密度有界条件下期望条件协方差的极小极大估计

In many scientific studies, evaluating the association between two responses requires adjusting for shared covariates. The expected conditional covariance measures this adjusted association and is used in conditional independence testing and treatment effect estimation. Researchers often estimate it using fitted conditional means, but removing the bias caused by the estimation errors of these conditional means remains a difficult task. This difficulty can increase when the…

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Network inference for SDEs with diverging dimension under small noise

小噪声下维度发散的网络随机微分方程推断

We consider inference for network stochastic differential equations in a small-noise, high-dimensional regime, where the diffusion coefficient vanishes with $\ep\to0$ while the network size and parameter dimension may diverge. We develop a minimum-distance estimation framework based on a deterministic measurement model that may omit nuisance terms in the drift, and derive a non-asymptotic error bound decomposing the estimation error into stochastic fluctuation, nuisance…

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Adversarial Estimation of Binary Configuration Probabilities under Sparse Dependence

稀疏依赖下二元配置概率的对抗估计

We consider the problem of estimating binary configuration probabilities, which is common in operations management applications, including product bundling, advertising, etc. Existing approaches typically model each assortment as a category and apply multinomial models to estimate the choice probabilities; while computationally convenient, these methods do not exploit independence structures in the joint distribution and may therefore be statistically inefficient when the…

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Optimal Community Recovery by Spectrally Initialized Variational EM in General Stochastic Block Models

一般随机块模型中谱初始化变分 EM 的最优社区恢复

We prove a Chernoff-exponent guarantee for the output of spectrally initialized batch variational EM after a prescribed iteration budget, without assuming global maximization of its variational objective. The iteration repeatedly estimates the entire block probability matrix and community proportions from the same sparse graph. We consider a fixed number of communities with proportions bounded away from zero and fixed, positive, distinct connectivity profiles; neither…

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Matched Triple-Differences: A Framework for Covariate Adjustment

匹配三重差分:协变量调整框架

A common empirical strategy in triple-differences (DDD) is to include either covariate trends or covariate levels to a three-way fixed effects (3WFE) regression. This strategy is typically motivated by the conditional parallel gaps assumption which assumes that deviations from parallel trends are similar among units with comparable observed covariates. We formally study both 3WFE specifications and show that, in general, neither consistently estimates the average treatment…

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Bootstrap Inference with a Randomly Assigned Regressor: Covariance Filtering and the Limits of Marginal Resampling

随机分配回归变量的自助法推断:协方差过滤与边际重抽样的局限

Random assignment can make ordinary least squares (OLS) inference insensitive to outcome dependence, yet iid resampling can still fail because assignment and resampling need not remove the same covariance terms. With binary treatment, the iid variance target differs from the sampling variance by exactly minus aggregate cross-unit covariance of treatment effects. Under a Gaussian first-order limit, positive covariance leads to over-rejection and negative covariance to…

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Structural Causal Models for Extremes: an Approach Based on Exponent Measures

We introduce a new formulation of structural causal models for extremes, called the extremal structural causal model (eSCM). Unlike conventional structural causal models, where randomness is governed by a probability distribution, eSCMs use an exponent measure, an infinite-mass law that naturally arises in the analysis of multivariate extremes. Central to this framework are activation variables, which abstract the single-big-jump principle, along with additional…

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Direct estimation and inference of differential Granger causality between two high-dimensional time series

Comparing dependence structures between two related multivariate time series is of fundamental interest in many scientific applications, where changes may occur in both directed temporal interactions and contemporaneous connectivity. Modeling each time series by a vector autoregressive (VAR) model, we propose a new framework for estimation and inference of differential Granger causality (DiffGC) and differential network (DiffNet) structures in high dimensions. The proposed…

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Partial Identification under Imperfect Measurement: A Distributionally Robust Approach

不完美测量下的部分识别:分布鲁棒方法

Imperfect measurements allow different underlying distributions to generate the same observations. Restrictions linking unobserved components can make it difficult to characterize all compatible distributions and compute the resulting range of parameter values. We ask how to construct computable parameter bounds and tighten them without additional data or stronger assumptions. We develop a general framework for partial identification under imperfect measurement based on…

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Towards causal effect estimation with learned instrument representations

Instrumental variable (IV) methods mitigate bias from unobserved confounding in observational causal inference but rely on the availability of a valid instrument, which can often be difficult or infeasible to identify in practice. In this paper, we propose a representation learning approach that constructs instrumental representations from observed covariates, which could enable IV-based estimation even in the absence of an explicit instrument. Our model (ZNet) achieves this…

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Network-Constrained Matching and Randomization-Based Inference for Causal Effects

网络约束匹配与因果效应的随机化推断

Matching is widely used to mimic randomized experiments by forming matched sets in which treated and control units differ only randomly with respect to observed covariates. However, when the study population consists of interconnected units from a single network or a small number of networks, matching solely on observed covariates may produce matched units that are more closely connected in the network than would occur by chance. This increased network proximity within…

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Neymanian inference in randomized experiments

随机实验中的 Neyman 式推断

In his seminal 1923 work, Neyman studied the variance estimation problem for the difference-in-means estimator of the average treatment effect in completely randomized experiments. He proposed a variance estimator that is conservative in general and unbiased under homogeneous treatment effects. While widely used under complete randomization, there is no unique or natural way to extend this estimator to more complex designs. To this end, we show that Neyman's estimator can be…

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Co-Supervised Tree Synthesis for Interpretable Subgroup Identification and Honest Treatment Effect Inference in Randomized Trials

共同监督树合成:随机试验中的可解释亚组识别与诚实处理效应推断

Identifying patient subgroups with heterogeneous treatment effects is central to precision medicine, yet existing approaches face a tension. Black-box methods estimate individualized effects well but yield no interpretable subgroups, while tree-based methods produce explicit partitions but are unstable and less accurate in moderate-sample trials. We propose CausalSynthTree, a co-supervised method in which black-box causal estimators guide construction of an interpretable…

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A Path-Dependent Agent-Based Microsimulation of Crime and Violence Reduction Policy Portfolios in Bolivia: Survey Calibration, Adaptive Emulator Ensembles, Global Sensitivity, Tempered MCMC, and Multi-Objective Policy Analysis

玻利维亚犯罪与暴力治理政策组合的路径依赖主体微观模拟

This study develops a survey-calibrated, path-dependent agent-based microsimulation for evaluating crime and violence reduction policies in Bolivia. A synthetic population is constructed from the 2025 Household Survey and the fourth-quarter 2025 Continuous Employment Survey using official expansion weights and cross-survey donor matching. The model combines heterogeneous agents, place-based risk, criminal adaptation, institutional capacity, community organization, and…

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Risk-Calibrated Balancing for High-Dimensional Causal Extrapolation

高维因果外推中的风险校准平衡

In observational causal inference, covariate balancing is widely used to reduce source-target covariate shift, but under weak overlap in high dimensions, stronger balance can induce concentrated weights and increase variance. Balance measures how well the target covariate distribution is represented, but does not by itself determine how reliably the counterfactual mean can be estimated. We develop risk-calibrated balancing for the average treatment effect on the treated,…

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Goodness-of-Fit Testing for Groupwise Spherical Error Structures

组内球形误差结构的拟合优度检验

The analysis of large data panels is important in econometrics and beyond. Prediction and inference methods for such data typically rely on simplifying model assumptions for the covariance structure of errors. One convenient assumption is what we call groupwise sphericity: that errors are uncorrelated across individuals and have constant variance within certain groups. While theoretically useful, in large panels groupwise sphericity is often too restrictive to apply in…

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Flexible Nonparametric Inference for Causal Effects under the Front-Door Model

前门模型下因果效应的灵活非参数推断

Evaluating causal treatment effects in observational studies requires addressing confounding. While the back-door criterion enables identification through adjustment for observed covariates, it fails in the presence of unmeasured confounding. The front-door criterion offers an alternative by leveraging variables that fully mediate the treatment effect and are unaffected by unmeasured confounders of the treatment-outcome pair. We develop novel one-step and targeted minimum…

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Pragmatic DML with AI-Learned Representations

使用 AI 学习表征的实用双重机器学习

Text, images, and other rich covariates are increasingly compressed into AI-learned representations and then used as controls in causal analysis. We study when this approach is valid and develop a practical framework for causal inference with learned representations. For a broad class of estimands, an imperfect representation distorts the target causal parameter by the product of two representation errors: one in the outcome regression and one in the balancing weight (or…

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Cross-Fitting Under Nonregularity: Normality and Inference via Locality

非正则情形下的交叉拟合:基于局部性的正态性与推断

Cross-fitting is routine in much of applied research. While conventional confidence intervals that ignore cross-fold dependence are asymptotically valid in several settings, they undercover in many applications that share a common form of nonregularity: from the classic cross-validation problem of testing whether a fitted model outperforms another, to testing for heterogeneous treatment effects with machine learning, to estimating the value of a potentially non-unique…

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Evaluating Threshold Policies in Randomized Threshold Designs: A Cautionary Tale for Regression Discontinuity Designs

随机阈值设计中的政策评估:对回归不连续设计的警示

Many policies assign treatment according to whether a score crosses a cutoff. Regression discontinuity (RD) designs identify the effect of treatment assignment, but the threshold policy itself may also reshape individuals' incentives, inducing behavioral responses that affect outcomes even holding treatment status fixed---a channel that conventional RD designs cannot capture. We develop a framework that exploits randomized variation in policy thresholds, together with…

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