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Randomized Experiments with Ambiguous Record Linkage

记录链接存在歧义时的随机实验

Randomized experiments are often linked to administrative data to measure outcomes, but coarse identifiers can leave multiple administrative records consistent with each experimental unit. We show that unbiased estimation of the sample average treatment effect is possible without resolving these ambiguous links or specifying an outcome model. Our key linkage requirement is that the true administrative outcome is contained among the candidate outcomes for each experimental…

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Rate-Based Causal Discovery for Heavy-Tailed Models

重尾模型中的基于比率的因果发现

In many complex systems, such as river networks and financial markets, extreme events propagate from causes to their effects, and the largest observations carry the most information about the underlying causal structure. Existing methods for causal discovery in extremes, however, are tailored to specific mechanisms, such as linear or max-linear models. This work develops causal discovery for heavy-tailed homogeneous structural causal models, a flexible class that contains…

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Comparing randomized trials

随机试验的比较:试验参与效应与效应迁移

Disagreements between randomized trials that address the same causal question pose challenges for the interpretation and synthesis of evidence. We sketch a causal framework for comparing the results of randomized trials that explicitly accommodates the possibility of trial engagement effects. Using counterfactual outcomes defined under joint interventions on treatment assignment and trial-related actions, we compare trial-native treatment effects with the effects transported…

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Identification and Estimation of Treatment Effects from Network Data with Confounded Social Links

社会网络数据中处理效应的识别与估计:当社会连接存在混杂时

In observational network data, the adoption of a treatment and the formation of social ties often depend on the same characteristics that affect outcomes. We propose a generalized propensity score for each unit's effective treatment, built from a model for treatment assignment and a dyadic model for network formation, which may include latent node heterogeneity. The score is marginalized over the network given covariates rather than conditioned on the realized network, and…

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Global Inference for High Dimensional Quantile Regression with Heterogeneity

异质性高维分位数回归的全局推断

Quantile regression has received considerable attention in high dimensional methodology due to its robustness and ability to accommodate heteroskedasticity. Despite this attention, current inferential methods for high dimensional quantile regression have significant limitations---only testing significance, testing at a single quantile at a time, or assuming homoskedasticity. To generalize the inferences that can be drawn in high dimensional quantile regression, we introduce…

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Inference for Heterogeneous Graphical Models using Doubly High-Dimensional Linear-Mixed Models

双重高维线性混合模型下异质图模型的推断

Inferring the structure of population-level functional connectivity networks from multi-subject functional magnetic resonance imaging data is essential for understanding the connectivity patterns underlying cognitive and behavioral functions. Graphical models provide a formal statistical framework for inferring the graph structure. However, the multi-level nature of functional magnetic resonance imaging data---where each level corresponds, for instance, to a…

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Is Inference Conditional on Not Rejecting a Pre-test Less Reliable than Unconditional Inference?

Researchers often report an estimate and confidence interval only if a specification test does not reject - for example, only if a pre-trend test supports a difference-in-differences design. Does this make the reported confidence interval less reliable? We show that when the identifying assumptions hold, the answer is no: conditional on passing the pre-test, the confidence interval may over-cover but cannot under-cover. When the assumptions fail, pre-testing can reduce…

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Choosing the Dictionary and Penalty for IV-LASSO

IV-LASSO 的工具变量字典与惩罚选择

Estimating the first stage of an instrumental variables (IV) model with the least absolute shrinkage and selection operator (LASSO) requires choosing a dictionary of technical instruments and a penalty level. First-order asymptotic theory offers no guidance on these choices, as any consistent implementation yields a structural parameter estimator with the same limiting distribution. In finite samples, however, these choices can have a substantial impact on the resulting…

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GMM for Panel Data Quantile Regression

面板数据分位数回归的GMM方法

This paper develops a smoothed generalized method of moments (GMM) framework for panel quantile models with individual-specific fixed-effects and endogenous regressors. By smoothing the indicator in the quantile moment conditions and profiling out the individual effects through smoothed individual quantile restrictions, the proposed estimator can be implemented using standard GMM algorithms. We establish consistency, asymptotic normality, and feasible inference under weak…

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Predicting the Distribution of Treatment Effects: A Covariate-Adjustment Approach

预测处理效应分布:协变量调整方法

Important questions for impact evaluation require knowledge not only of average effects, but of the distribution of treatment effects. The inability to observe individual counterfactuals makes answering these empirical questions challenging. I propose an inference approach for points of the distribution of treatment effects that uses predicted counterfactuals through covariate adjustment. I provide finite-sample valid inference using sample-splitting and asymptotically valid…

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Nested Instrumental Variables Analysis: Switcher Average Treatment Effect, Identification, Efficient Estimation and Generalizability

嵌套工具变量分析:转换者平均处理效应及可推广性

Instrumental variables (IVs) are widely used to estimate causal effects from non-randomized data. A canonical example is a randomized trial with noncompliance, in which the randomized treatment assignment serves as an IV for the non-ignorable treatment received. Under a monotonicity assumption, a valid IV nonparametrically identifies the average treatment effect among a latent complier subgroup, whose generalizability is often under debate. In many studies, there exist…

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Simple Standard Errors for Complicated (Quasi-)Experimental Designs

复杂(准)实验设计下的简单标准误

We develop standard errors for estimates of causal effects in settings where the distribution of treatment exposures is known but potentially exhibits complicated dependence patterns across units. Such dependence arises, for example, in settings with spillovers/interference across units or when the treatment assignment is spatially correlated. Our variance estimator generalizes several properties of the Neyman variance estimator for completely randomized experiments to…

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A Theory of the Mechanics of Information: Generalization Through Measurement of Uncertainty (Learning is Measuring)

Traditional machine learning relies on explicit models and domain assumptions, often limiting flexibility and interpretability. We introduce a "model-free" framework of instance-based learning using surprisal (information theoretic uncertainty) to directly analyze and perform inferences from raw data, eliminating distribution modeling, reducing bias, and enabling efficient updates including direct edits and deletion of training data. By quantifying relevance through…

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Formalization and consistency of clone-censor-weight

克隆—删失—加权方法的形式化与一致性

Target trial emulation has become a standard framework for causal inference from observational data. Within this paradigm, the clone-censor-weight (CCW) methodology provides a practical way to deal with complex treatment and adherence definitions when treatment regimes are not distinguishable at baseline. Despite its increasing use, the statistical interpretation of CCW remains limited. In this work, we formalize the CCW methodology from a statistical viewpoint based on…

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The Panel Information Matrix Test

面板信息矩阵检验

The Information Matrix (IM) test is a natural specification check for likelihood-based models, yet cross-sectional implementations are often badly sized, confound neglected heterogeneity with distributional misspecification, and require third derivatives. We develop the panel information matrix (PIM) test for models with fixed effects. Explicit fixed effects isolate functional-form misspecification from time-invariant unobserved heterogeneity. Although the profile maximum…

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Prediction-Powered Data Fusion for Treatment Effect Estimation

用于处理效应估计的预测驱动数据融合

Randomized controlled trials (RCTs) identify treatment effects without confounding but are often small, whereas observational studies (OBS) are large but may be confounded. Many estimators combining a small RCT with a large OBS have been developed for the average treatment effect (ATE) and the conditional ATE (CATE). However, existing ATE estimators either make assumptions on the OBS or do not borrow enough power from them. The CATE has been studied less than the ATE.…

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Estimation of Average Effects in Short $T$ Heterogeneous Panels

短时间维度异质性面板中的平均效应估计

The commonly used two-way fixed effects estimator is biased under correlated heterogeneity and can lead to misleading inference. The mean group estimator proposed by \cite{PesaranSmith1995} is robust to correlated heterogeneity but requires the individual estimators to have second-order moments that could fail if the number of estimated coefficients ($k$) is close to the time dimension ($T$) of the panel. This paper focuses on panels where $T-k$ is mall (including $T=k$),…

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Overstuffed sandwiches and separation anxiety: finite-sample variance estimation for penalized GEE with near-separated binary data

近分离二元数据中惩罚GEE的有限样本方差估计

Penalized generalized estimating equations (PGEE) stabilize point estimation for longitudinal binary data under near-separation, but inference still depends on how the sandwich variance is corrected. Existing corrections for PGEE can overadjust in high-leverage directions, require restrictive pooling assumptions, or add global regularization without explaining the bias. We establish first-order asymptotics for PGEE along convergent interior-root sequences and derive a matrix…

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Scalable likelihood-based inference for limited dependent variable models

受限因变量模型中可扩展的似然推断

Limited dependent variable models are central to empirical economics, but likelihood-based inference is infeasible when likelihoods involve high-dimensional integration over latent variables. This paper proposes Stochastically Estimated Gradient Ascent (SEGA), a scalable estimation approach for limited dependent variable models. Using Fisher's identity, SEGA replaces the intractable likelihood score with an unbiased augmented data score evaluated at a single conditional draw…

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Robust Causal Inference for EHR-based Studies of Point Exposures with Missingness in Eligibility Criteria

Missingness in variables that define study eligibility criteria is a seldom addressed challenge in electronic health record (EHR)-based settings. Patients with incomplete eligibility information are typically excluded from analysis without consideration of the (implicit) assumptions being made, leaving study conclusions subject to potential selection bias. In an effort to ascertain eligibility for more patients, researchers may look back further in time prior to study…

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When Does Inexact Matching Ensure Balance and Inference without Adjustment?

非精确匹配何时能在无需调整的情况下保证平衡与有效推断?

One-to-one matching without replacement is a classical approach to constructing comparable treated and control samples in the design of observational studies. It pairs each treated unit with a distinct control while minimizing a covariate distance objective. With continuous covariates, the matched pairs generally remain inexact, which contributes to bias in downstream analysis. Its key theoretical properties, such as the resulting imbalance between matched pairs and when it…

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Treatment Effect Modification by Latent Classes

潜在类别对处理效应的调节

Many treatments have effects that plausibly vary by latent classes. For example, the effect of personalized video recommendations may be stronger for users who seek a new discovery than for users seeking to rewatch something familiar. In the context of user journeys on digital platforms, we can conceptualize user moods as dynamic latent states that lead to distinct action distributions. Because mood is unobserved, we infer it from a user's pre-treatment actions using a…

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Adaptively Combining Randomized and External Control Data Using a Mixture Prior in the Presence of Heterogeneity

存在异质性时利用混合先验自适应结合随机试验与外部对照

When resources are limited in a randomized trial, a common strategy is to augment data from the control arm with external controls. We propose a hybrid group sequential Bayesian design that uses this approach to compare time-to-event distributions. The design allows between-treatment effects to differ between patient subgroups, and adaptively combines subgroups that have similar hazard functions. The aim is to reduce the control arm sample size without compromising the…

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Policy Learning with Weak Signals

弱信号下的政策学习

Policy learning in digital experimentation faces three challenges: weak signal-to-noise ratios, rich covariate spaces, and massive data volumes. We formalize this regime by modeling treatment-effect estimates from increasingly fine covariate partitions as Gaussian observations with bounded signal-to-noise ratios. We establish that, in general, the optimal treatment policy is not learnable in this setting. Even learning the optimal policy value suffers from impractically slow…

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