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近端因果框架下的个体化函数型处理规则AI 解读

Estimating individualized treatment regimes (ITRs) is fundamental in data-driven personalized decision-making problems, such as precision medicine. Most of the ITR literature either focuses on categorical/continuous treatments or assumes no unmeasured confounding. In this paper, we make the first attempt to estimate the optimal individualized functional treatment regime (IFTR) for observational data where the treatment is a function and unmeasured confounding is present. We…

观察数据因果推断中的最优传输入门AI 解读

The theory of optimal transportation has developed into a powerful and elegant framework for comparing probability distributions, with wide-ranging applications in all areas of science. The fundamental idea of analyzing probabilities by comparing their underlying state space naturally aligns with the core idea of causal inference, where understanding and quantifying counterfactual states is paramount. Despite this intuitive connection, explicit research at the intersection…

层级复合终点的连续加权胜率比AI 解读

Hierarchical composite endpoints are commonly used in clinical trials when component out- comes differ in clinical importance. The win ratio compares patients across treatment groups according to a pre-specified order of clinical priority and has an intuitive interpretation. A strict hierarchical rule, however, uses a lower-priority endpoint only when all higher-priority endpoints are tied or non-informative. This may reduce power when the treatment effect is mainly ex-…

生存结局协变量调整中平衡加权与增广方法的联系AI 解读

Covariate adjustment improves the efficiency of treatment-effect analyses in randomized clinical trials, provided the adjustment targets the correct quantity. For time-to-event endpoints, two marginal targets are of primary interest: the log-rank test for the presence of a treatment effect and the marginal hazard ratio for its magnitude. Existing covariate adjustment approaches reach these targets by different ways. Augmentation adjusts the log-rank score by regressing…

带节点乘性效应的网络潜在空间模型AI 解读

Latent space models represent network nodes as points in a geometric space, with connection probabilities determined by distances between latent positions under a fixed metric, typically Euclidean, spherical, or hyperbolic. We generalize the classical formulation by introducing nodal multiplicative effects motivated by a local deformation of the latent metric. This modification approximates a conformal deformation of the metric tensor while preserving the logistic predictor…

目标加权 Neyman 分配：总体迁移下异质性处理效应的实验设计AI 解读

Randomized experiments are often run in one population to guide decisions in another. Allocating by experimental proportions wastes budget on groups that rarely appear in deployment, whereas allocating by deployment proportions under-samples groups that are hard to measure precisely. We propose \textbf{TWNA} (Target-Weighted Neyman Allocation), a two-stage stratified design that uses pilot estimates of group--arm outcome variances to allocate final-stage sample sizes and…

以历史选择作为实际考虑集的 Logit 模型一致估计AI 解读

A key challenge in choice modeling lies in specifying the consideration set, the subset of alternatives that individuals actually evaluate when making choices, which is unobserved (latent) to the researcher. The classical homo economicus assumption posits that individuals assess the full universal set of alternatives, a behaviorally implausible premise. Practical options include directly asking individuals, which introduces behavioral biases; treating the consideration set…

稀疏双边互动模型中的互补性AI 解读

This paper studies complementarities in two-sided interaction models when only a sparse subset of potential matches is realized. I introduce the Tukey model, adding one complementarity parameter to two-way fixed effects. Variation within a four-cycle in the observed matching network identifies this parameter, while connectedness permits identification of agent productivities. I propose a cycle-based estimator that avoids estimating latent productivities. The estimator is…

网络干扰下异质性处理效应：基于节点连通性的非参数方法AI 解读

In network settings, interference between units makes causal inference more challenging as outcomes may depend on the treatments received by others in the network. Typical estimands in network settings focus on treatment effects aggregated across individuals in the population. We propose a framework for estimating node-wise counterfactual means, allowing for more granular insights into the impact of network structure on treatment effect heterogeneity. We develop a doubly…

随机对照试验中预后协变量调整的第一阶段估计不确定性AI 解读

Prognostic covariate adjustment (PROCOVA) is a two-sample two-stage estimation method for covariate adjustment in randomized controlled trials. In the first stage, a prognostic score, defined as the conditional expectation of an outcome given covariates under the control treatment, is estimated using historical data. In the second stage, analysis of covariance with the estimated prognostic score and treatment assignment as explanatory variables is performed, and the average…

对抗式因果干预证伪AI 解读

Generative models can reproduce an observational distribution while encoding an incorrect causal structure. We study a sequential game in which a structural causal generator proposes observational and interventional distributions, while an adversarial experimentalist selects interventions intended to maximally falsify the generator. The discriminator is therefore not merely a real-versus-synthetic classifier: it is indexed by an intervention and tests whether the generator…

分类处理与二元近端结局微随机试验的因果效应估计及样本量计算AI 解读

Micro-randomized trials (MRTs) provide a framework for evaluating the marginal and moderated effects of mobile health (mHealth) interventions. In many applications, treatments take the form of categorical variables with multiple levels, such as different message contents or delivery strategies. Many scientifically meaningful longitudinal outcomes in mHealth studies are binary, such as whether a participant opens an app, engages with content, or completes a target behavior…

利用负对照结局事件时间提高传染病预防试验效率AI 解读

Baseline covariate adjustment can enhance the efficiency of randomized trials by improving precision of treatment effect estimates. However, the precision gain depends on how strongly the baseline covariates are prognostic for the primary outcome. In randomized trials of infectious disease prevention interventions (e.g., vaccines or passively administered antibodies), an individual's exposure to the pathogen is a leading prognostic factor but is rarely measurable at…

网络模型中基于成对差分的分布回归方法AI 解读

I develop an estimation and inference framework for distribution regression in dyadic network settings with two-way fixed effects that vary across thresholds of the outcome. I show that identification of the structural parameters is achieved through binarization of the outcome at each threshold, and estimate the model by conditional maximum likelihood, which "differences out" the fixed effects and circumvents the incidental parameter problem. The estimator remains…

利用代理变量对因果效应进行部分识别AI 解读

Proximal causal inference is a framework for evaluating the causal effects in the presence of unmeasured confounding. For point identification, it leverages a pair of proxy variables to identify a bridge function that matches the dependence of potential outcomes or treatment variables on the hidden factors to corresponding functions of observed proxies. Unique identification requires that proxies are sufficiently relevant for hidden factors, a requirement that has previously…

获益—风险评价中结局期望排序概率的统一因果推断框架AI 解读

We developed a unified covariate-adjusted causal inference framework for estimating the desirability of outcome ranking (DOOR) probability for benefit-risk evaluation in randomized trials and observational studies. The framework expresses the DOOR probability as a bilinear functional of the marginal ordinal outcome distributions under the two treatment strategies, estimates conditional ordinal distributions through sequential risk-set hazards, and derives the efficient…

网络实验的设计型极小极大理论AI 解读

Network experiments are used throughout the social and medical sciences to investigate causal effects under the presence of interference. While a large body of work has developed improved statistical procedures, the fundamental limits of statistical estimation in these settings is less well understood. In this paper, we develop and investigate a design-based theory of minimax risk for network experiments under an arbitrary neighborhood interference model. Our notion of…

二元结局下 Fisher 尖锐零假设的差分隐私检验AI 解读

Across many disciplines, causal inference often relies on randomized experiments with binary outcomes. In such experiments, often analysts are interested in testing Fisher's sharp null hypothesis, i.e., the treatment has zero effect on the outcome for every study subject. Sometimes the outcomes are sensitive and must be kept confidential, for example, when they comprise physical or mental health measurements. Releasing test statistics or p-values computed with the…

处理组特异非高斯误差下平均处理效应的结构化半参数估计AI 解读

This paper studies average treatment effect (ATE) estimation for continuous outcomes when the treatment-covariate mean is structured but the error distributions are unknown and may differ across treatment arms in scale, skewness, or tail behavior. We introduce a semiparametric model with a finite-dimensional mean, or a prespecified basis expansion, and separate unrestricted additive error laws for treated and control outcomes. The central theoretical contribution is the…

不完整数据下的不平等界限AI 解读

We study inequality measures when outcomes are observed only in intervals, as in historical tabulations, privacy-protected grouped data, and modern surveys. We develop a nonparametric framework for sharp identification and inference with grouped and interval-valued data, covering brackets and overlapping intervals. For a class of inequality indices, sharp bounds are attained by discrete distributions with finite support, reducing the problem to optimization;…

类别型工具变量模型：刻画、部分识别与统计推断AI 解读

We study categorical instrumental variable (IV) models with instrument, treatment and outcome taking finitely many values. We derive a simple closed-form characterization of the set of joint distributions of potential outcomes that are compatible with a given observed data distribution in terms of a minimal set of inequalities. These inequalities unify several different IV models defined by versions of the independence and exclusion restriction assumptions. They lead to…

对哪个目标量最好？时变处理的纵向匹配与目标试验模拟已知真值基准AI 解读

On a non-collapsible survival mechanism, longitudinal-matching and target-trial-emulation methods are not competing estimators of one truth but answers to different causal questions, so a benchmark that scores them against a single "true hazard ratio" fabricates bias. We provide the direct comparison of relative efficiency, variance estimation, and model sensitivity that reviews find lacking. On a deliberately non-collapsible continuous-time Cox mechanism with known truth,…

对提前反应与平行趋势违背的联合敏感性分析AI 解读

Two key identifying assumptions used to justify difference-in-differences are parallel trends and no anticipation, yet both may fail in practice. I propose a class of assumptions that constitute deviations from no anticipation and derive closed-form, sharp bounds for several common treatment effect parameters while simultaneously relaxing parallel trends. Deviations from both assumptions are jointly disciplined using observed pre-trends. When some anticipation is imposed,…

利用因果森林估计出行方式转变的异质性AI 解读

Objectives: While causal analysis of travel behavior is an emerging field, estimating heterogeneity in mode choice through causal modeling remains unexplored. This study demonstrates the application of a novel causal method, causal forest, to quantify the heterogeneity in travel mode choice shifts caused by the COVID-19 pandemic. Methods: We applied causal forests, a non-parametric causal machine learning method, to 802,935 trip records from the 2017 and 2022 waves of the…