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A Unified Framework for Specification Tests of Continuous Treatment Effect Models

连续处理效应模型设定检验的统一框架

We propose a general framework for the specification testing of continuous treatment effect models. We assume a general residual function, which includes the average and quantile treatment effect models as special cases. The null models are identified under the unconfoundedness condition and contain a nonparametric weighting function. We propose a test statistic for the null model in which the weighting function is estimated by solving an expanding set of moment equations.…

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Online Testing of Subgroup Treatment Effects Based on Value Difference

基于价值差异的子群处理效应在线检验

Online A/B testing plays a critical role in the high-tech industry to guide product development and accelerate innovation. It performs a null hypothesis statistical test to determine which variant is better. However, a typical A/B test presents two problems: (i) a fixed-horizon framework inflates the false-positive errors under continuous monitoring; (ii) the homogeneous effects assumption fails to identify a subgroup with a beneficial treatment effect. In this paper, we…

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Estimating the causal effect of an intervention in a time series setting: the C-ARIMA approach

时间序列干预因果效应的估计:C-ARIMA 方法

The Rubin Causal Model (RCM) is a framework that allows to define the causal effect of an intervention as a contrast of potential outcomes. In recent years, several methods have been developed under the RCM to estimate causal effects in time series settings. None of these makes use of ARIMA models, which are instead very common in the econometrics literature. In this paper, we propose a novel approach, C-ARIMA, to define and estimate the causal effect of an intervention in a…

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A generalized bootstrap procedure of the standard error and confidence interval estimation for inverse probability of treatment weighting

逆概率处理加权标准误与置信区间估计的广义自助法

The inverse probability of treatment weighting (IPTW) approach is commonly used in propensity score analysis to infer causal effects in regression models. Due to oversized IPTW weights and errors associated with propensity score estimation, the IPTW approach can underestimate the standard error of causal effect. To remediate this, bootstrap standard errors have been recommended to replace the IPTW standard error, but the ordinary bootstrap (OB) procedure might still result…

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Multiple imputation and test-wise deletion for causal discovery with incomplete cohort data

不完整队列数据因果发现中的多重插补与逐检验删除

Causal discovery algorithms estimate causal graphs from observational data. This can provide a valuable complement to analyses focussing on the causal relation between individual treatment-outcome pairs. Constraint-based causal discovery algorithms rely on conditional independence testing when building the graph. Until recently, these algorithms have been unable to handle missing values. In this paper, we investigate two alternative solutions: Test-wise deletion and multiple…

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Bayesian Sensitivity Analysis for Missing Data Using the E-value

利用 E-value 对缺失数据开展贝叶斯敏感性分析

Sensitivity Analysis is a framework to assess how conclusions drawn from missing outcome data may be vulnerable to departures from untestable underlying assumptions. We extend the E-value, a popular metric for quantifying robustness of causal conclusions, to the setting of missing outcomes. With motivating examples from partially-observed Facebook conversion events, we present methodology for conducting Sensitivity Analysis at scale with three contributions. First, we…

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SIMPLE: Statistical Inference on Membership Profiles in Large Networks

SIMPLE:大型网络中成员归属特征的统计推断

Network data is prevalent in many contemporary big data applications in which a common interest is to unveil important latent links between different pairs of nodes. Yet a simple fundamental question of how to precisely quantify the statistical uncertainty associated with the identification of latent links still remains largely unexplored. In this paper, we propose the method of statistical inference on membership profiles in large networks (SIMPLE) in the setting of…

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Causal Inference in the Time of Covid-19

COVID-19 疫情时期的因果推断

In this paper we develop statistical methods for causal inference in epidemics. Our focus is in estimating the effect of social mobility on deaths in the Covid-19 pandemic. We propose a marginal structural model motivated by a modified version of a basic epidemic model. We estimate the counterfactual time series of deaths under interventions on mobility. We conduct several types of sensitivity analyses. We find that the data support the idea that reduced mobility causes…

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Nonparametric Heterogeneous Treatment Effect Estimation in Repeated Cross Sectional Designs

重复截面设计中的非参数异质性处理效应估计

Identifying heterogeneity in a population's response to a health or policy intervention is crucial for evaluating and informing policy decisions. We propose a novel heterogeneous treatment effect estimator in the difference-in-differences design with repeated cross sectional data, where we observe different samples of a population at two time periods separated by the onset of a policy intervention, as well as samples of a population that serves as the control. Our estimator…

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Distributional conformal prediction

分布共形预测

We propose a robust method for constructing conditionally valid prediction intervals based on models for conditional distributions such as quantile and distribution regression. Our approach can be applied to important prediction problems including cross-sectional prediction, k-step-ahead forecasts, synthetic controls and counterfactual prediction, and individual treatment effects prediction. Our method exploits the probability integral transform and relies on permuting…

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Combining Real-World and Randomized Control Trial Data Using Data-Adaptive Weighting via the On-Trial Score

通过试验参与评分自适应加权整合真实世界与随机试验数据

Clinical trials with a hybrid control arm (a control arm constructed from a combination of randomized patients and real-world data on patients receiving usual care in standard clinical practice) have the potential to decrease the cost of randomized trials while increasing the proportion of trial patients given access to novel therapeutics. However, due to stringent trial inclusion criteria and differences in care and data quality between trials and community practice, trial…

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Transfer learning of individualized treatment rules from experimental to real-world data

从实验数据向真实世界迁移学习个体化治疗规则

Individualized treatment effect lies at the heart of precision medicine. Interpretable individualized treatment rules (ITRs) are desirable for clinicians or policymakers due to their intuitive appeal and transparency. The gold-standard approach to estimating the ITRs is randomized experiments, where subjects are randomized to different treatment groups and the bias is minimized to the extent possible. However, experimental data are limited in external validity because of…

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Choice Set Confounding in Discrete Choice

离散选择中的选择集混杂

Standard methods in preference learning involve estimating the parameters of discrete choice models from data of selections (choices) made by individuals from a discrete set of alternatives (the choice set). While there are many models for individual preferences, existing learning methods overlook how choice set assignment affects the data. Often, the choice set itself is influenced by an individual's preferences; for instance, a consumer choosing a product from an online…

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Matrix Completion, Counterfactuals, and Factor Analysis of Missing Data

矩阵补全、反事实与缺失数据的因子分析

This paper proposes an imputation procedure that uses the factors estimated from a tall block along with the re-rotated loadings estimated from a wide block to impute missing values in a panel of data. Assuming that a strong factor structure holds for the full panel of data and its sub-blocks, it is shown that the common component can be consistently estimated at four different rates of convergence without requiring regularization or iteration. An asymptotic analysis of the…

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On the Distinction Between "Conditional Average Treatment Effects" (CATE) and "Individual Treatment Effects" (ITE) Under Ignorability Assumptions

可忽略性假设下条件平均治疗效应与个体治疗效应的区别

Recent years have seen a swell in methods that focus on estimating "individual treatment effects". These methods are often focused on the estimation of heterogeneous treatment effects under ignorability assumptions. This paper hopes to draw attention to the fact that there is nothing necessarily "individual" about such effects under ignorability assumptions and isolating individual effects may require additional assumptions. Such individual effects, more often than not, are…

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Weighted asymmetric least squares regression with fixed-effects

带固定效应的加权非对称最小二乘回归

The fixed-effects model estimates the regressor effects on the mean of the response, which is inadequate to summarize the variable relationships in the presence of heteroscedasticity. In this paper, we adapt the asymmetric least squares (expectile) regression to the fixed-effects model and propose a new model: expectile regression with fixed-effects $(\ERFE).$ The $\ERFE$ model applies the within transformation strategy to concentrate out the incidental parameter and…

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Controlling for Unmeasured Confounding in Panel Data Using Minimal Bridge Functions: From Two-Way Fixed Effects to Factor Models

以最小桥函数控制面板数据中的未观测混杂:从双向固定效应到因子模型

We develop a new approach for identifying and estimating average causal effects in panel data under a linear factor model with unmeasured confounders. Compared to other methods tackling factor models such as synthetic controls and matrix completion, our method does not require the number of time periods to grow infinitely. Instead, we draw inspiration from the two-way fixed effect model as a special case of the linear factor model, where a simple difference-in-differences…

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Improving Inference from Simple Instruments through Compliance Estimation

通过依从率估计改进简单工具变量的统计推断

Instrumental variables (IV) regression is widely used to estimate causal treatment effects in settings where receipt of treatment is not fully random, but there exists an instrument that generates exogenous variation in treatment exposure. While IV can recover consistent treatment effect estimates, they are often noisy. Building upon earlier work in biostatistics (Joffe and Brensinger, 2003) and relating to an evolving literature in econometrics (including Abadie et al.,…

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Estimating populational-average hazard ratios in the presence of unmeasured confounding

存在未测量混杂时总体平均风险比的估计

The Cox regression model and its associated hazard ratio (HR) are frequently used for summarizing the effect of treatments on time to event outcomes. However, the HR's interpretation strongly depends on the assumed underlying survival model. The challenge of interpreting the HR has been the focus of a number of recent works. Besides, several alternative measures have been proposed in order to deal with these concerns. The marginal Cox regression models include an…

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Discussion on "Bayesian Regression Tree Models for Causal Inference: Regularization, Confounding, and Heterogeneous Effects" by Hahn, Murray and Carvalho

对《用于因果推断的贝叶斯回归树模型》的讨论

Hahn et al. (2020) offers an extensive study to explicate and evaluate the performance of the BCF model in different settings and provides a detailed discussion about its utility in causal inference. It is a welcomed addition to the causal machine learning literature. I will emphasize the contribution of the BCF model to the field of causal inference through discussions on two topics: 1) the difference between the PS in the BCF model and the Bayesian PS in a Bayesian…

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Model-assisted analyses of cluster-randomized experiments

整群随机实验的模型辅助分析

Cluster-randomized experiments are widely used due to their logistical convenience and policy relevance. To analyze them properly, we must address the fact that the treatment is assigned at the cluster level instead of the individual level. Standard analytic strategies are regressions based on individual data, cluster averages, and cluster totals, which differ when the cluster sizes vary. These methods are often motivated by models with strong and unverifiable assumptions,…

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Robust Density Power Divergence Estimates for Panel Data Models

面板数据模型的稳健密度幂散度估计

The panel data regression models have become one of the most widely applied statistical approaches in different fields of research, including social, behavioral, environmental sciences, and econometrics. However, traditional least-squares-based techniques frequently used for panel data models are vulnerable to the adverse effects of the data contamination or outlying observations that may result in biased and inefficient estimates and misleading statistical inference. In…

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A Structural Model of Business Card Exchange Networks

名片交换网络的结构模型

Social and professional networks affect labor market dynamics, knowledge diffusion and new business creation. To understand the determinants of how these networks are formed in the first place, we analyze a unique dataset of business cards exchanges among a sample of over 240,000 users of the multi-platform contact management and professional social networking tool for individuals Eight. We develop a structural model of network formation with strategic interactions, and we…

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Optimal Covariate Balancing Conditions in Propensity Score Estimation

倾向得分估计中的最优协变量平衡条件

Inverse probability of treatment weighting (IPTW) is a popular method for estimating the average treatment effect (ATE). However, empirical studies show that the IPTW estimators can be sensitive to the misspecification of the propensity score model. To address this problem, researchers have proposed to estimate propensity score by directly optimizing the balance of pre-treatment covariates. While these methods appear to empirically perform well, little is known about how the…

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