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使用地理编码微观数据的双重差分AI 解读

This paper formalizes a common approach for estimating effects of treatment at a specific location using geocoded microdata. This estimator compares units immediately next to treatment (an inner-ring) to units just slightly further away (an outer-ring). I introduce intuitive assumptions needed to identify the average treatment effect among the affected units and illustrates pitfalls that occur when these assumptions fail. Since one of these assumptions requires knowledge of…

单人随机试验的样本量计算AI 解读

N-of-1 trials, single participant trials in which multiple treatments are sequentially randomized over the study period, can give direct estimates of individual-specific treatment effects. Combining n-of-1 trials gives extra information for estimating the population average treatment effect compared with randomized controlled trials and increases precision for individual-specific treatment effect estimates. In this paper, we present a procedure for designing n-of-1 trials.…

处理时点变化下双重差分与比较中断时间序列设计的统计功效AI 解读

This article develops new closed-form variance expressions for power analyses for commonly used difference-in-differences (DID) and comparative interrupted time series (CITS) panel data estimators. The main contribution is to incorporate variation in treatment timing into the analysis. The power formulas also account for other key design features that arise in practice: autocorrelated errors, unequal measurement intervals, and clustering due to the unit of treatment…

依赖条件下控制错误发现率的大规模实验处理效应检测AI 解读

Online controlled experiments (also known as A/B Testing) have been viewed as a golden standard for large data-driven companies since the last few decades. The most common A/B testing framework adopted by many companies use "average treatment effect" (ATE) as statistics. However, it remains a difficult problem for companies to improve the power of detecting ATE while controlling "false discovery rate" (FDR) at a predetermined level. One of the most popular FDR-control…

固定 T 下交互固定效应线性面板模型的估计AI 解读

This paper studies the estimation of linear panel data models with interactive fixed effects, where one dimension of the panel, typically time, may be fixed. To this end, a novel transformation is introduced that reduces the model to a lower dimension, and, in doing so, relieves the model of incidental parameters in the cross-section. The central result of this paper demonstrates that transforming the model and then applying the principal component (PC) estimator of…

β-Intact-VAE：有限重叠下因果效应的识别与估计AI 解读

As an important problem in causal inference, we discuss the identification and estimation of treatment effects (TEs) under limited overlap; that is, when subjects with certain features belong to a single treatment group. We use a latent variable to model a prognostic score which is widely used in biostatistics and sufficient for TEs; i.e., we build a generative prognostic model. We prove that the latent variable recovers a prognostic score, and the model identifies…

结果变量随机右删失时的两阶段最小二乘估计AI 解读

This note develops a simple two-stage least squares (2SLS) procedure to estimate the causal effect of some endogenous regressors on a randomly right censored outcome in the linear model. The proposal replaces the usual ordinary least squares regressions of the standard 2SLS by weighted least squares regressions. The weights correspond to the inverse probability of censoring. We show consistency and asymptotic normality of the estimator. The estimator exhibits good finite…

图结构辅助的分组网络自回归模型：贝叶斯非参数方法AI 解读

Vector autoregression model is ubiquitous in classical time series data analysis. With the rapid advance of social network sites, time series data over latent graph is becoming increasingly popular. In this paper, we develop a novel Bayesian grouped network autoregression model to simultaneously estimate group information (number of groups and group configurations) and group-wise parameters. Specifically, a graphically assisted Chinese restaurant process is incorporated…

大量代理控制变量AI 解读

A recent literature considers causal inference using noisy proxies for unobserved confounding factors. The proxies are divided into two sets that are independent conditional on the confounders. One set of proxies are `negative control treatments' and the other are `negative control outcomes'. Existing work applies to low-dimensional settings with a fixed number of proxies and confounders. In this work we consider linear models with many proxy controls and possibly many…

纵向观察数据中的生存因果推断：序贯试验与边际结构模型AI 解读

Longitudinal observational patient data can be used to investigate the causal effects of time-varying treatments on time-to-event outcomes. Several methods have been developed for controlling for the time-dependent confounding that typically occurs. The most commonly used is inverse probability weighted estimation of marginal structural models (MSM-IPTW). An alternative, the sequential trials approach, is increasingly popular, in particular in combination with the target…

警惕基尼指数：一种新的不平等测度AI 解读

The Gini index underestimates inequality for heavy-tailed distributions: for example, a Pareto distribution with exponent 1.5 (which has infinite variance) has the same Gini index as any exponential distribution (a mere 0.5). This is because the Gini index is relatively robust to extreme observations: while a statistic's robustness to extremes is desirable for data potentially distorted by outliers, it is misleading for heavy-tailed distributions, which inherently exhibit…

大量弱工具变量下的统计推断AI 解读

We develop a concept of weak identification in linear IV models in which the number of instruments can grow at the same rate or slower than the sample size. We propose a jackknifed version of the classical weak identification-robust Anderson-Rubin (AR) test statistic. Large-sample inference based on the jackknifed AR is valid under heteroscedasticity and weak identification. The feasible version of this statistic uses a novel variance estimator. The test has uniformly…

厘清整群随机试验的选择偏差：目标参数与估计AI 解读

In cluster randomized trials, patients are typically recruited after clusters are randomized, and the recruiters and patients may not be blinded to the assignment. This often leads to differential recruitment and consequently systematic differences in baseline characteristics of the recruited patients between intervention and control arms, inducing post-randomization selection bias. We rigorously define causal estimands in the presence of selection bias. We elucidate the…

因果推断中的数据整合AI 解读

Integrating data from multiple heterogeneous sources has become increasingly popular to achieve a large sample size and diverse study population. This paper reviews development in causal inference methods that combines multiple datasets collected by potentially different designs from potentially heterogeneous populations. We summarize recent advances on combining randomized clinical trial with external information from observational studies or historical controls, combining…

利用多变量孟德尔随机化分离共享聚集遗传预测因子的性状效应AI 解读

When genetic variants in a gene cluster are associated with a disease outcome, the causal pathway from the variants to the outcome can be difficult to disentangle. For example, the chemokine receptor gene cluster contains genetic variants associated with various cytokines. Associations between variants in this cluster and stroke risk may be driven by any of these cytokines. Multivariable Mendelian randomization is an extension of standard univariable Mendelian randomization…

通过局部图学习因果结构AI 解读

We consider the problem of learning causal structures in sparse high-dimensional settings that may be subject to the presence of (potentially many) unmeasured confounders, as well as selection bias. Based on the structure found in common families of large random networks and examining the representation of local structures in linear structural equation models (SEM), we propose a new local notion of sparsity for consistent structure learning in the presence of latent and…

随机试验推断向目标人群扩展时的异质性处理效应回归估计AI 解读

Methods for extending -- generalizing or transporting -- inferences from a randomized trial to a target population involve conditioning on a large set of covariates that is sufficient for rendering the randomized and non-randomized groups exchangeable. Yet, decision-makers are often interested in examining treatment effects in subgroups of the target population defined in terms of only a few discrete covariates. Here, we propose methods for estimating subgroup-specific…

因果矩阵补全AI 解读

Matrix completion is the study of recovering an underlying matrix from a sparse subset of noisy observations. Traditionally, it is assumed that the entries of the matrix are "missing completely at random" (MCAR), i.e., each entry is revealed at random, independent of everything else, with uniform probability. This is likely unrealistic due to the presence of "latent confounders", i.e., unobserved factors that determine both the entries of the underlying matrix and the…

通过嵌入结合离散选择模型与神经网络：形式、可解释性及表现AI 解读

This study proposes a novel approach that combines theory and data-driven choice models using Artificial Neural Networks (ANNs). In particular, we use continuous vector representations, called embeddings, for encoding categorical or discrete explanatory variables with a special focus on interpretability and model transparency. Although embedding representations within the logit framework have been conceptualized by Pereira (2019), their dimensions do not have an absolute…

不完美工具变量下处理效应的非参数界AI 解读

This paper extends the identification results in Nevo and Rosen (2012) to nonparametric models. We derive nonparametric bounds on the average treatment effect when an imperfect instrument is available. As in Nevo and Rosen (2012), we assume that the correlation between the imperfect instrument and the unobserved latent variables has the same sign as the correlation between the endogenous variable and the latent variables. We show that the monotone treatment selection and…

推广与迁移分析中的亚组效应估计AI 解读

Methods for extending -- generalizing or transporting -- inferences from a randomized trial to a target population involve conditioning on a large set of covariates that is sufficient for rendering the randomized and non-randomized groups exchangeable. Yet, decision-makers are often interested in examining treatment effects in subgroups of the target population defined in terms of only a few discrete covariates. Here, we propose methods for estimating subgroup-specific…

通过营养干预试验的现实模拟评估目标最大似然估计的稳健性AI 解读

Several recently developed methods have the potential to harness machine learning in the pursuit of target quantities inspired by causal inference, including inverse weighting, doubly robust estimating equations and substitution estimators like targeted maximum likelihood estimation. There are even more recent augmentations of these procedures that can increase robustness, by adding a layer of cross-validation (cross-validated targeted maximum likelihood estimation and…

离散情形下因果推断的自动化方法AI 解读

When causal quantities cannot be point identified, researchers often pursue partial identification to quantify the range of possible values. However, the peculiarities of applied research conditions can make this analytically intractable. We present a general and automated approach to causal inference in discrete settings. We show causal questions with discrete data reduce to polynomial programming problems, and we present an algorithm to automatically bound causal effects…

医疗补助人群推广分析中的条件跨设计综合估计量AI 解读

While much of the causal inference literature has focused on addressing internal validity biases, both internal and external validity are necessary for unbiased estimates in a target population of interest. However, few generalizability approaches exist for estimating causal quantities in a target population when the target population is not well-represented by a randomized study but is reflected when additionally incorporating observational data. To generalize to a target…