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生存结局治疗效应的随机化推断AI 解读

The log-rank test and Kaplan--Meier plot are standard tools for analyzing time-to-event data in randomized clinical trials, yet neither provides a summary of the magnitude of the treatment effect. Practitioners typically fill this gap by reporting a hazard ratio from a Cox proportional-hazards model or an acceleration factor from an accelerated failure time (AFT) model, but both require assumptions beyond those needed for the log-rank test or Kaplan--Meier estimator. We…

条件随机分组下同伴效应的估计与推断AI 解读

Empirical studies of peer effects often exploit conditional random assignment to peer groups within urns. We develop a GMM framework for estimation and inference in this setting. The framework separately identifies endogenous and contextual peer effects and nests tests of random peer-group assignment as a special case. It permits unknown heteroskedasticity and corrects finite-urn bias in variance estimation. Its asymptotic theory allows the number of peer groups to grow…

部分干扰下用于倾向得分估计的混合效应结果自适应 LassoAI 解读

Interference occurs when one individual's treatment or exposure affects another individual's outcome. In particular, we assume partial interference, where individuals are divided into groups such that there is no interference between individuals in different groups. In observational studies, inverse probability weighting (IPW) based on propensity scores is often used for causal effect estimation. However, under partial interference, the group-level propensity score must be…

个体与整群随机试验中存活期间目标量的双重稳健估计AI 解读

Randomized trials in chronic disease settings often measure treatment benefit through recurrent non-fatal events that are truncated by death, where conventional summaries either discard recurrences, conflate the treatment effect with survival, or treat death as censoring and forfeit a causal interpretation. While-alive estimands measure event burden per unit time alive, but doubly robust estimation for the exposure-weighted while-alive rate remains undeveloped, particularly…

利用生成式人工智能对非结构化数据开展因果推断AI 解读

We introduce GenAI-Powered Inference (GPI), a statistical framework for both causal and predictive inference using unstructured data, including text and images. GPI leverages open-source Generative Artificial Intelligence (GenAI) models---such as large language models and diffusion models---not only to generate unstructured data at scale but also to extract low-dimensional representations that are guaranteed to capture their underlying structure. Applying machine learning to…

权重不确定性下的合成控制：稳健识别与统计推断AI 解读

The synthetic control method estimates causal effects by comparing a treated unit with weighted controls matched on its pre-treatment trajectory. However, validity can be compromised when highly correlated controls leave the synthetic weights weakly determined or when treated-control relationships shift after treatment. We propose a new estimand, the weight-robust treatment effect, defined as the optimizer of a worst-case optimization problem over an uncertainty class of…

确定因果方向需要多少样本？双变量 LiNGAM 的尖锐极小极大界AI 解读

We study how many observations are needed to determine the causal direction between two linearly related variables. Classical LiNGAM theory shows that independent non-Gaussian disturbances identify the direction, but does not quantify the difficulty when the causal effect is weak or the disturbances are nearly Gaussian. Let $β$ bound the absolute structural coefficient from below, let $ν$ measure each standardized disturbance's distance from Gaussianity, and let the…

存在处理不依从与多个中介时零膨胀纵向数据的因果中介分析AI 解读

Understanding whether a digital marketing campaign is effective is central to designing effective customer engagement strategies. We analyze a large-scale, longitudinal promotional email campaign conducted by a U.S.\ retailer to evaluate how value-added incentives, such as free shipping, compare with traditional price discounts in influencing customer purchasing behavior. The analysis is complicated by non-compliance, due to not opening emails, multiple longitudinal…

修正线性单元回归AI 解读

This paper develops a regression framework for analyzing integrated conditional distribution and quantile functions. The proposed method, termed rectified linear unit (ReLU) regression, projects the ReLU-transformed outcome onto covariates and admits a closed-form estimator. Its population regression function is the best linear approximation to the integrated conditional distribution function of the outcome, and the corresponding convex conjugate, obtained via the…

中介分析的能量平衡权重AI 解读

Causal mediation analysis requires reconstruction of counterfactual distributions to estimate natural direct and indirect effects. Inverse probability weighting estimators rely on models for treatment assignment and mediator density ratios, whereas moment balancing approaches require researchers to specify in advance which functions of the covariates and mediators should be balanced. We propose Energy Balancing Weights for Mediation Analysis (EBWMA), which targets the joint…

选择偏差下恢复平均处理效应的图形规则AI 解读

Selection bias is a major obstacle toward valid causal inference in epidemiology. Over the past decade, several graphical rules based on causal diagrams have been proposed as sufficient identification conditions for addressing selection bias and recovering causal effects. However, these simple graphical rules are typically coupled with specific identification strategies and estimators. In this article, we show two important cases of selection bias that fall outside the scope…

多区域临床试验中区域处理效应的有效估计AI 解读

A multi-regional clinical trial (MRCT) is a single clinical trial conducted in multiple regions simultaneously under a common protocol, which may be used to support parallel submissions to multiple regulatory authorities. For a regional regulatory authority, treatment effects defined specifically for its own region are more relevant to consider than overall treatment effects based on all regions included in an MRCT. A regional treatment effect can be estimated consistently…

空间场景下设计型推断中的结果建模AI 解读

In the face of spatial interference, researchers are often interested in estimating treatment effects at specific points located in space. Wang et al. (2025) and Pollmann (2023) provide design-based frameworks for estimating spillover effects on points located across a range of distances from interventions. Although these frameworks are design-based, we show their proposed estimands rely on outcomes that are directly unobservable and therefore, require outcome modeling. When…

GFCM：面向因果发现的尾部敏感混合类型条件独立检验AI 解读

Constraint-based causal discovery like PC and FCI depends on its conditional independence test. Partial correlation and the Generalised Covariance Measure (GCM) detect only the conditional covariance of residuals, so they miss dependence in the mean's nonlinear part, the scale, and the tails. Tests that detect more are biased inside PC, not scalable, only continuous, or not aimed at the tails. Our Generalised Feature Covariance Measure (GFCM) is valid, sensitive beyond…

随机潜在选择与潜在结果AI 解读

Applied econometricians typically model each individual as having fixed outcomes under treatment and control and, in instrumental-variables (IV) settings, fixed treatment decisions under each value of the instrument. This paper asks what changes when outcomes and treatment allocations or choices are stochastic at the individual level. In the model, each individual has a stable (but possibly stochastic) response type consisting of two objects: a treatment choice probability…

多中心随机试验中的稳健协变量调整AI 解读

Augmented inverse probability weighting and G-computation with canonical generalized linear models have become increasingly popular for estimating the average treatment effect (ATE) in randomized experiments. These methods leverage outcome prediction models to adjust for imbalances in baseline covariates across treatment arms, improving power compared to unadjusted analyses, while controlling Type I error, even when models are misspecified. In multi-center trials they are…

异质主体模型的有限信息估计AI 解读

We develop a method for estimating and testing a single block of a macroeconomic model with heterogeneous agents, without placing assumptions on the structure of the rest of the economy. In a large class of models, individual agents' decisions depend on the macroeconomy only through their expectations of the evolution of a finite-dimensional vector of "sufficient statistics" (e.g., asset returns or aggregate earnings). Our estimator selects the structural parameters that…

随机实验的锐极小极大理论AI 解读

We study minimax-optimal designs and estimators for estimating the sample average treatment effect in finite population randomized experiments, where both design and estimator are unrestricted. For binary potential outcomes, we show this minimax risk is equivalent to the minimax risk $ρ_n^*$ of an estimation problem with $2$ unknown parameters. We leverage this reduction to establish a second-order risk expansion $ρ_n^* = n^{-1} - Cn^{-4/3} + o_n(n^{-4/3})$ for an explicit…

未知干扰下利用面板数据学习处理效应AI 解读

When comparison units may also respond to treatment, panel comparisons reflect both the treatment effect and spillovers. If the interference pattern is unknown, observed outcomes alone do not separate the two. I characterize what can nevertheless be learned from panel outcomes under general restrictions, without requiring an exposure mapping or prior classification of affected donors. The framework scales validity bounds for every convex donor weight by its fit before…

广义贝叶斯政策学习AI 解读

This study proposes a General Bayes framework for policy learning. We consider decision problems in which a decision-maker chooses an action from a given set to maximize expected welfare. Typical examples include treatment choice and portfolio optimization. In such problems, the statistical target is a decision rule, and predicting each potential outcome is not necessarily of primary interest. We formulate this policy-learning problem through loss-based Bayesian updating.…

基于图神经网络的网络数据因果中介分析AI 解读

Causal mediation analysis is typically formulated under no interference, an assumption often violated in networked populations. We develop a nonparametric framework for a single large observed network that allows simultaneous treatment and mediator spillovers and high-dimensional network confounding. Exposure and mediator mappings define causal estimands without restricting the true interference mechanism, separating own from spillover effects without prespecified…

测量误差下分布函数、跳跃及区间概率的估计AI 解读

We consider the classical additive measurement-error model $X=Y+Z$, where the latent random variable $Y$ has unknown distribution $F_Y$ and the error $Z$ has a known distribution. We develop direct estimators for three functionals of $F_Y$: (i) $F_Y(x)$ at continuity points; (ii) interval probabilities $F_Y(y)-F_Y(x)$ when $x<y$ are continuity points; and (iii) the size of a jump at a prespecified discontinuity. We derive non-asymptotic bias and variance bounds, and…

部分识别下处理选择的局部渐近理论AI 解读

We provide a new asymptotic framework to derive approximately optimal treatment assignments when sampling noise from data is compounded by fundamental uncertainty due to partial identification. We recenter the reduced-form parameter around its \emph{least-favorable} configuration and consider drifting parameter sequences that yield both diminishing levels of sampling uncertainty and of partial identification. We characterize the limiting decision problem as a normal location…

群变换污染下结构化结果的因果推断：可观测商空间、无损约化与精确随机化检验AI 解读

Structured potential outcomes such as microscopy images may be recorded after an unknown, unit-specific transformation. If that transformation can depend on treatment, covariates or the intrinsic outcome, raw-coordinate analyses may mix biological effects with acquisition geometry. We study the unrestricted observation model X = Γ . Y(A) and characterize its observable information: a target is uniformly recoverable exactly when it is constant on group orbits, while a Borel…