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删失选择模型的分布回归方法AI 解读

We develop a distribution regression model with a censored selection rule, offering a semi-parametric generalization of the Heckman selection model. Our approach applies to the entire distribution, extending beyond the mean or median, accommodates non-Gaussian error structures, and allows for heterogeneous effects of covariates on both the selection and outcome distributions. By employing a censored selection rule, our model can uncover richer selection patterns according to…

不要丢弃单例：独立流失下配对实验的有效推断AI 解读

Pairwise randomization can yield substantial efficiency gains in experiments. Yet methodological guidance cautions against pairwise randomization, especially in settings with attrition, partly because common practices for estimation (i.e., pair fixed effects) imply discarding data from incomplete pairs thus exacerbating data loss from attrition. This practice of dropping incomplete pairs reduces statistical power of tests as well as precision of estimates, in paired…

存在溢出效应的实验与准实验：基于设计的检验和推断AI 解读

Economic policies rarely affect only their direct targets. To study these spillovers, researchers summarize who else was treated with a simple exposure measure, such as the share of treated neighbors within a radius. But for many settings, economic theory provides little guidance on choosing the functional form (e.g., ring) of that measure or its parameters (e.g., radius). We show that the data can inform both choices. Correctly specified exposure measures imply…

用于季节性传染病干预因果评估的贝叶斯疫情对齐AI 解读

Seasonal infectious-disease interventions are commonly evaluated with interrupted time-series or pre--post designs that align epidemics by calendar week. When epidemic onset, speed or peak timing differs between seasons, such comparisons confound a shift in epidemic phase with a change in disease burden. We propose a Bayesian causal count model in which season-specific affine transformations map calendar time to a latent epidemic clock, and intervention effects are estimated…

通过构造工具变量实现测量误差稳健的因果推断AI 解读

Measurement error can often be harmful when estimating causal effects. Two scenarios in which this is the case are in the estimation of (a) the average treatment effect when confounders are measured with error and (b) the natural indirect effect when the exposure and/or confounders are measured with error. Methods adjusting for measurement error typically require external data or knowledge about the measurement error distribution. Here, we propose methodology not requiring…

质心参照马氏匹配：大规模观察研究的因果推断框架AI 解读

Matching for causal inference can be computationally expensive at scale and can silently change the target population when overlap is limited. We propose Centroid-Referenced Mahalanobis Matching (CRM), which replaces global pairwise search with stratified sampling in two reference coordinates: each unit's Mahalanobis distance from the treated centroid and its Fisher coordinate along the treated-control mean shift. All covariates enter through the treated covariance geometry;…

个体化治疗效应预测校准的非参数评估AI 解读

An important aspect of the performance of algorithms that predict individualized treatment effects (ITE) is moderate calibration, i.e., the average treatment effect among individuals with predicted treatment effect of z being equal to z. The assessment of moderate calibration is challenging on two fronts: counterfactual responses are unobserved, and quantifying the conditional response function for models that generate continuous predicted values requires regularization.…

中断时间序列的因果中介分析：稳定中介加权及车辆排放政策应用AI 解读

Population-level policies are introduced at a fixed time and evaluated from a single series of aggregate outcomes, and the interrupted time series design estimates the total shift in an outcome after the intervention. When the policy is expected to act through a measurable pathway, the total effect is less informative than its decomposition into direct and indirect effects. We formulate causal mediation for a single interrupted time series and study stabilized mediator…

实验设计的极限：超越低维的协变量平衡AI 解读

We study how fast experimental designs can approach the semiparametric efficiency bound in finite samples, as measured by the excess variance of unadjusted treatment effect estimation. We prove an impossibility theorem: under weak conditions, no design can approach the variance bound uniformly over smooth outcome models unless covariate dimension $d \ll \log n$. Even in experiments with thousands of units, this permits only a handful of covariates. Motivated by this, we…

后验漂移与潜在隐藏混杂下的试验证据迁移AI 解读

Randomized trials provide internally valid treatment-effect evidence, but trial participants may not represent the target population. In contrast, observational studies are often closer to the target population, but their treatment assignment may be affected by possible hidden confounding. We develop a robust posterior-drift framework for estimating the average treatment effect in an observational target population when exact conditional-effect transportability may fail. The…

识别变异集中时固定效应回归的精确推断AI 解读

In fixed-effect regressions with many groups, fixed effects can absorb most identifying variation, leaving a handful of observations to carry what remains. When variation is this concentrated, conventional $t$-tests can reject a true null more than half the time, and any fixed critical value is either invalid or so conservative it has essentially no power. This paper builds an exact test from the design alone. A \textit{nuisance-annihilating contrast} is a linear combination…

森林核平衡权重：由结局引导的因果推断特征AI 解读

While balancing covariates between groups is central for observational causal inference, selecting which features to balance remains a challenging problem. Kernel balancing is a promising approach that first estimates a kernel that captures similarity across units and then balances a (possibly low-dimensional) summary of that kernel, indirectly learning important features to balance. In this paper, we propose forest kernel balancing, which leverages the underappreciated fact…

adjustedCurves：在 R 中估计混杂调整后的生存曲线AI 解读

Kaplan-Meier curves stratified by treatment allocation are the most popular way to depict causal effects in studies with right-censored time-to-event endpoints. If the treatment is randomly assigned and the sample size of the study is adequate, this method produces unbiased estimates of the population-averaged counterfactual survival curves. However, in observational studies, this is no longer the case. Instead, specific methods that allow adjustment for confounding must be…

学习该学什么：结合实验与观察证据的实验设计AI 解读

Experiments deliver credible treatment-effect estimates but, because they are costly, are often restricted to specific sites, small populations, or particular mechanisms. A common practice across several fields is therefore to combine experimental estimates with reduced-form or structural external (observational) evidence to answer broader policy questions, such as those involving general equilibrium effects or external validity. We develop a unified framework for the design…

时变调节效应的选择后推断AI 解读

Causal effect moderation investigates how the effect of interventions (or treatments) on outcome variables changes based on observed characteristics of individuals, known as potential effect moderators. With advances in data collection, datasets containing many observed features as potential moderators have become increasingly common. High-dimensional analyses often lack interpretability, with important moderators masked by noise, while low-dimensional, marginal analyses…

调查抽样与因果推断中的最优控制变量AI 解读

We propose a family of control variate estimators for variance reduction in design-based survey sampling and causal inference, with and without interference. In these settings, inverse probability weighting (IPW) estimators are widely used, but may have large variance when sampling, treatment, or exposure probabilities are small. Building on the observation that several common estimators, including the Hajek estimator, the normalized estimator, the augmented inverse…

加权最小二乘估计量对遗漏变量的敏感性AI 解读

We introduce tools for assessing the sensitivity, to unobserved confounding, of a common estimator of causal effects that employs weights: the weighted linear regression of the outcome on the treatment and observed covariates. This estimator's bias is a function of two intuitive weighted partial $R^2$ values: (i) the proportion of weighted variance in the treatment that unobserved confounding explains given the covariates and (ii) the proportion of weighted variance in the…

目标点处的条件随机占优检验AI 解读

This paper introduces a test for conditional stochastic dominance between two distributions at prespecified values of a conditioning covariate, referred to as target points. The test uses a one-sided Kolmogorov--Smirnov statistic computed from induced order statistics, the outcomes attached to the conditioning observations closest to the target point, and compares it to a critical value that, given the number of neighbors, requires no resampling, kernel smoothing, or…

临床试验序贯多重插补：仅有基线数据的早期退出者扩展AI 解读

Under the ICH E9 (R1) addendum, treatment policy strategies for intercurrent events target the treatment effect regardless of treatment discontinuation. Sequential multiple imputation (MI) models that condition each visit's imputation on discontinuation status or pattern reduce bias relative to mixed models and standard MI, but require every subject to contribute at least one post-baseline observation, an assumption violated by subjects who withdraw before any post-baseline…

多元有序选择中依赖关系的结构AI 解读

When individuals make simultaneous decisions across multiple ordered dimensions, standard multivariate ordered choice models impose narrow bracketing: each dimension is decided as if the others did not exist. We develop a general rectangular structure model capturing broad bracketing while nesting the standard model. The framework introduces two layers of dependence, one through the decision-threshold structure and the other through the correlation of latent utilities. We…

分位数限制、揭示排序与多项选择的边界AI 解读

This paper analyzes when choice probabilities reveal rankings of deterministic utility indices in semiparametric discrete choice models. It begins with binary choice, where quantile thresholds guarantee ranking recovery, and shows that such thresholds can arise either from behavioral departures from utility maximization (e.g., limited attention) under exchangeable unobservables, or from non-exchangeable unobservables under standard utility maximization. These behavioral and…

NP-LEAP：借用历史数据的非参数潜在可交换性先验AI 解读

Bayesian dynamic borrowing (BDB) methods leverage historical data to reduce treatment effect uncertainty, yet existing approaches rely on parametric outcome models susceptible to misspecification. We propose the nonparametric latent exchangeability prior (NP-LEAP), an outcome-agnostic, assumption-lean framework to borrow information from historical data. The NP-LEAP performs individual-level exchangeability assessment, inducing Bayesian model averaging over all possible…

主方案试验：从目标量定义到治疗效应的稳健推断AI 解读

Master protocol trials use a single overarching protocol to evaluate multiple interventions, diseases, or disease subtypes, where individuals are often randomized to different subsets of intervention arms based on individual characteristics, enrollment timing, and intervention availability. While offering increased flexibility, this constrained and non-uniform intervention assignment poses two fundamental inferential challenges: the precise definition of treatment effects…

似然模型偶然参数问题的 Neyman 正交化方法AI 解读

A popular approach to perform inference on a target parameter in the presence of nuisance parameters is to construct estimating equations that are orthogonal to the nuisance parameters, in the sense that their expected first derivative is zero. Such first-order orthogonalization allows the estimator of the nuisance parameters to converge at a slower-than-parametric rate. It may, however, not suffice when the nuisance parameters are very imprecisely estimated. Leading…