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数据驱动的切换实验：理论权衡与经验贝叶斯设计AI 解读

We study the design and analysis of switchback experiments conducted on a single aggregate unit. The design problem is to partition the continuous time space into intervals and switch treatments between intervals, in order to minimize the estimation error of the treatment effect. We show that the estimation error depends on four factors: carryover effects, periodicity, serially correlated outcomes, and impacts from simultaneous experiments. We derive a rigorous bias-variance…

带阈值识别的生物标志物引导自适应富集生存试验设计AI 解读

Biomarker-guided designs are increasingly used to evaluate personalized treatments based on patients' biomarker status in Phase II and III clinical trials. With adaptive enrichment, these designs can improve the efficiency of evaluating the treatment effect in biomarker-positive patients by increasing their proportion in the randomized trial. While time-to-event outcomes are often used as the primary endpoint to measure treatment effects for a new therapy in severe diseases…

基于最优传输的多元随机占优及模型基准比较AI 解读

Stochastic dominance is an important concept in probability theory, econometrics and social choice theory for robustly modeling agents' preferences between random outcomes. While many works have been dedicated to the univariate case, little has been done in the multivariate scenario, wherein an agent has to decide between different multivariate outcomes. By exploiting a characterization of multivariate first stochastic dominance in terms of couplings, we introduce a…

调整潜在同质性以识别治疗社区中的同伴影响AI 解读

We investigate peer role model influence on successful graduation from Therapeutic Communities (TCs) for substance abuse and criminal behavior. We use data from 3 TCs that kept records of exchanges of affirmations among residents and their precise entry and exit dates, allowing us to form peer networks and define a causal effect of interest. The role model effect measures the difference in the expected outcome of a resident (ego) who can observe one of their peers graduate…

可识别异方差噪声模型下的有效因果发现AI 解读

Capturing the underlying structural causal relations represented by Directed Acyclic Graphs (DAGs) has been a fundamental task in various AI disciplines. Causal DAG learning via the continuous optimization framework has recently achieved promising performance in terms of both accuracy and efficiency. However, most methods make strong assumptions of homoscedastic noise, i.e., exogenous noises have equal variances across variables, observations, or even both. The noises in…

用于估计含潜变量因果结构的广义独立噪声条件AI 解读

We investigate the task of learning causal structure in the presence of latent variables, including locating latent variables and determining their quantity, and identifying causal relationships among both latent and observed variables. To this end, we propose a Generalized Independent Noise (GIN) condition for linear non-Gaussian acyclic causal models that incorporate latent variables, which establishes the independence between a linear combination of certain measured…

面板数据中的异质性处理效应AI 解读

We address a core problem in causal inference: estimating heterogeneous treatment effects using panel data with general treatment patterns. Many existing methods either do not utilize the potential underlying structure in panel data or have limitations in the allowable treatment patterns. In this work, we propose and evaluate a new method that first partitions observations into disjoint clusters with similar treatment effects using a regression tree, and then leverages the…

广义结果自适应 Lasso 的 Oracle 性质AI 解读

The generalized outcome-adaptive lasso (GOAL) is a variable selection for high-dimensional causal inference proposed by Baldé et al. [2023, {\em Biometrics} {\bfseries 79(1)}, 514--520]. When the dimension is high, it is now well established that an ideal variable selection method should have the oracle property to ensure the optimal large sample performance. However, the oracle property of GOAL has not been proven. In this paper, we show that the GOAL estimator enjoys the…

使用秩变量回归的因果解释AI 解读

In studies of educational production functions or intergenerational mobility, it is common to transform the key variables into percentile ranks. Yet, it remains unclear what the regression coefficient estimates with ranks of the outcome or the treatment. In this paper, we derive effective causal estimands for a broad class of commonly-used regression methods, including the ordinary least squares (OLS), two-stage least squares (2SLS), difference-in-differences (DiD), and…

未观测异质性引起的时间滞后偏差：随访起点不同的治疗组与对照组比较AI 解读

In comparative effectiveness research, treated and control patients might have a different start of follow-up as treatment is often started later in the disease trajectory. This typically occurs when data from treated and controls are not collected within the same source. Only patients who did not yet experience the event of interest whilst in the control condition end up in the treatment data source. In case of unobserved heterogeneity, these treated patients will have a…

提高平均处理效应跨人群迁移的估计效率AI 解读

We develop flexible, semiparametric estimators of the average treatment effect (ATE) transported to a new population ("target population") that offer potential efficiency gains. Transport may be of value when the ATE may differ across populations. We consider the setting where differences in the ATE are due to differences in the distribution of baseline covariates that modify the treatment effect ("effect modifiers"). First, we propose a collaborative one-step semiparametric…

捆绑商品补贴的学习效应：半参数方法AI 解读

Can temporary subsidies to bundles induce long-run changes in demand due to learning about the quality of one of the constituent goods? This paper provides theoretical support and empirical evidence on this mechanism. Theoretically, we introduce a model where an agent learns about the quality of an innovation through repeated consumption. We then assess the predictions of our theory in a randomised experiment in a ridesharing platform. The experiment subsidised car trips…

DoWhy-GCM：用于图因果模型推断的 DoWhy 扩展AI 解读

We present DoWhy-GCM, an extension of the DoWhy Python library, which leverages graphical causal models. Unlike existing causality libraries, which mainly focus on effect estimation, DoWhy-GCM addresses diverse causal queries, such as identifying the root causes of outliers and distributional changes, attributing causal influences to the data generating process of each node, or diagnosis of causal structures. With DoWhy-GCM, users typically specify cause-effect relations via…

面向人类偏好的语言模型优化是一个因果推断问题AI 解读

As large language models (LLMs) see greater use in academic and commercial settings, there is increasing interest in methods that allow language models to generate texts aligned with human preferences. In this paper, we present an initial exploration of language model optimization for human preferences from direct outcome datasets, where each sample consists of a text and an associated numerical outcome measuring the reader's response. We first propose that language model…

将增广平衡权重表示为线性回归AI 解读

We provide a novel characterization of augmented balancing weights, also known as automatic debiased machine learning (AutoDML). These popular doubly robust or de-biased machine learning estimators combine outcome modeling with balancing weights - weights that achieve covariate balance directly in lieu of estimating and inverting the propensity score. When the outcome and weighting models are both linear in some (possibly infinite) basis, we show that the augmented estimator…

基于回归的近端因果推断AI 解读

Negative controls are increasingly used to evaluate the presence of potential unmeasured confounding in observational studies. Beyond the use of negative controls to detect the presence of residual confounding, proximal causal inference (PCI) was recently proposed to de-bias confounded causal effect estimates, by leveraging a pair of treatment and outcome negative control or confounding proxy variables. While formal methods for statistical inference have been developed for…

DoubleML：R 中双重机器学习的面向对象实现AI 解读

The R package DoubleML implements the double/debiased machine learning framework of Chernozhukov et al. (2018). It provides functionalities to estimate parameters in causal models based on machine learning methods. The double machine learning framework consist of three key ingredients: Neyman orthogonality, high-quality machine learning estimation and sample splitting. Estimation of nuisance components can be performed by various state-of-the-art machine learning methods…

用于因果效应估计的校准与共形倾向得分AI 解读

Propensity scores are commonly used to estimate treatment effects from observational data. We argue that the probabilistic output of a learned propensity score model should be calibrated -- i.e., a predictive treatment probability of 90% should correspond to 90% of individuals being assigned the treatment group -- and we propose simple recalibration techniques to ensure this property. We prove that calibration is a necessary condition for unbiased treatment effect estimation…

从短期实验推断持续处理的长期因果效应AI 解读

We study inference on the long-term causal effect of a continual exposure to a novel intervention, which we term a long-term treatment, based on an experiment involving only short-term observations. Key examples include the long-term health effects of regularly-taken medicine or of environmental hazards and the long-term effects on users of changes to an online platform. This stands in contrast to short-term treatments or "shocks," whose long-term effect can reasonably be…

LongBet：面板数据中的异质性处理效应估计AI 解读

This paper introduces a novel approach for estimating heterogeneous treatment effects of binary treatment in panel data, particularly focusing on short panel data with large cross-sectional data and observed confoundings. In contrast to traditional literature in difference-in-differences method that often relies on the parallel trend assumption, our proposed model does not necessitate such an assumption. Instead, it leverages observed confoundings to impute potential…

小规模先导实验下奈曼分配的表现AI 解读

The Neyman Allocation is used in many papers on experimental design, which typically assume that researchers have access to large pilot studies. This may be unrealistic. To understand the properties of the Neyman Allocation with small pilots, we study its behavior in an asymptotic framework that takes pilot size to be fixed even as the size of the main wave tends to infinity. Our analysis shows that the Neyman Allocation can lead to estimates of the ATE with higher…

用于多元时间序列因果预测的组合式动态建模AI 解读

Theoretical developments in sequential Bayesian analysis of multivariate dynamic models underlie new methodology for causal prediction. This extends the utility of existing models with computationally efficient methodology, enabling routine exploration of Bayesian counterfactual analyses with multiple selected time series as synthetic controls. Methodological contributions also define the concept of outcome adaptive modelling to monitor and inferentially respond to changes…

存在潜在混杂变量时 LiNGAM 模型的因果效应识别AI 解读

We study the generic identifiability of causal effects in linear non-Gaussian acyclic models (LiNGAM) with latent variables. We consider the problem in two main settings: When the causal graph is known a priori, and when it is unknown. In both settings, we provide a complete graphical characterization of the identifiable direct or total causal effects among observed variables. Moreover, we propose efficient algorithms to certify the graphical conditions. Finally, we propose…

迈向因果基础模型：因果推断与注意力机制的对偶关系AI 解读

Foundation models have brought changes to the landscape of machine learning, demonstrating sparks of human-level intelligence across a diverse array of tasks. However, a gap persists in complex tasks such as causal inference, primarily due to challenges associated with intricate reasoning steps and high numerical precision requirements. In this work, we take a first step towards building causally-aware foundation models for treatment effect estimations. We propose a novel,…