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疾病预防的成本效果分析：结直肠癌筛查案例AI 解读

Cancer Screening has been widely recognized as an effective strategy for preventing the disease. Despite its effectiveness, determining when to start screening is complicated, because starting too early increases the number of screenings over lifetime and thus costs but starting too late may miss the cancer that could have been prevented. Therefore, to make an informed recommendation on the age to start screening, it is necessary to conduct cost-effectiveness analysis to…

多阈值断点回归设计下的安全政策学习AI 解读

The regression discontinuity (RD) design is widely used for program evaluation with observational data. The primary focus of the existing literature has been the estimation of the local average treatment effect at the existing treatment cutoff. In contrast, we consider policy learning under the RD design. Because the treatment assignment mechanism is deterministic, learning better treatment cutoffs requires extrapolation. We develop a robust optimization approach to finding…

交叉协方差函数的大规模多重检验及其在函数网络模型中的应用AI 解读

The estimation of functional networks through functional covariance and graphical models have recently attracted increasing attention in settings with high dimensional functional data, where the number of functional variables p is comparable to, and maybe larger than, the number of subjects. However, the existing methods all depend on regularization techniques, which make it unclear how the involved tuning parameters are related to the number of false edges. In this paper,…

秩变换子抽样：多重数据划分与可交换 p 值的推断AI 解读

Many testing problems are readily amenable to randomised tests such as those employing data splitting. However despite their usefulness in principle, randomised tests have obvious drawbacks. Firstly, two analyses of the same dataset may lead to different results. Secondly, the test typically loses power because it does not fully utilise the entire sample. As a remedy to these drawbacks, we study how to combine the test statistics or p-values resulting from multiple random…

大规模双重机器学习：预测客户行为的因果影响AI 解读

Causal Impact (CI) of customer actions are broadly used across the industry to inform both short- and long-term investment decisions of various types. In this paper, we apply the double machine learning (DML) methodology to estimate the CI values across 100s of customer actions of business interest and 100s of millions of customers. We operationalize DML through a causal ML library based on Spark with a flexible, JSON-driven model configuration approach to estimate CI at…

存在长期存活者时基于目标量的推断AI 解读

In this article, we develop nonparametric inference methods for comparing survival data across two samples, which are beneficial for clinical trials of novel cancer therapies where long-term survival is a critical outcome. These therapies, including immunotherapies or other advanced treatments, aim to establish durable effects. They often exhibit distinct survival patterns such as crossing or delayed separation and potentially leveling-off at the tails of survival curves,…

高维分位数预测的稀疏 PAC-Bayes 方法AI 解读

Quantile regression, a robust method for estimating conditional quantiles, has advanced significantly in fields such as econometrics, statistics, and machine learning. In high-dimensional settings, where the number of covariates exceeds sample size, penalized methods like lasso have been developed to address sparsity challenges. Bayesian methods, initially connected to quantile regression via the asymmetric Laplace likelihood, have also evolved, though issues with posterior…

有限监督下的增益建模AI 解读

Estimating causal effects in e-commerce tends to involve costly treatment assignments which can be impractical in large-scale settings. Leveraging machine learning to predict such treatment effects without actual intervention is a standard practice to diminish the risk. However, existing methods for treatment effect prediction tend to rely on training sets of substantial size, which are built from real experiments and are thus inherently risky to create. In this work we…

双重机器学习与面板数据：潜力、陷阱及可能的解决方案AI 解读

Estimating causal effect using machine learning (ML) algorithms can help to relax functional form assumptions if used within appropriate frameworks. However, most of these frameworks assume settings with cross-sectional data, whereas researchers often have access to panel data, which in traditional methods helps to deal with unobserved heterogeneity between units. In this paper, we explore how we can adapt double/debiased machine learning (DML) (Chernozhukov et al., 2018)…

用于异质性因果推断的分类变量有向图贝叶斯非参数混合模型AI 解读

Quantifying causal effects of exposures on outcomes, such as a treatment and a disease respectively, is a crucial issue in medical science for the administration of effective therapies. Importantly, any related causal analysis should account for all those variables, e.g. clinical features, that can act as risk factors involved in the occurrence of a disease. In addition, the selection of targeted strategies for therapy administration requires to quantify such treatment…

利用祖先关系学习含高斯噪声的线性无环因果模型AI 解读

This paper discusses algorithms for learning causal DAGs. The PC algorithm makes no assumptions other than the faithfulness to the causal model and can identify only up to the Markov equivalence class. LiNGAM assumes linearity and continuous non-Gaussian disturbances for the causal model, and the causal DAG defining LiNGAM is shown to be fully identifiable. The PC-LiNGAM, a hybrid of the PC algorithm and LiNGAM, can identify up to the distribution-equivalence pattern of a…

政策学习中的多臂老虎机算法：方法、实现与福利表现AI 解读

Static supervised learning-in which experimental data serves as a training sample for the estimation of an optimal treatment assignment policy-is a commonly assumed framework of policy learning. An arguably more realistic but challenging scenario is a dynamic setting in which the planner performs experimentation and exploitation simultaneously with subjects that arrive sequentially. This paper studies bandit algorithms for learning an optimal individualised treatment…

实现最优收敛率的自适应分裂平衡随机森林AI 解读

In this paper, we propose a new random forest algorithm that constructs the trees using a novel adaptive split-balancing method. Rather than relying on the widely-used random feature selection, we propose a permutation-based balanced splitting criterion. The adaptive split balancing forest (ASBF), achieves minimax optimality under the Lipschitz class. Its localized version, which fits local regressions at the leaf level, attains the minimax rate under the broad Hölder class $\mathcal{H}^{q,β}$…

持续混杂下通过数据结合开展长期因果推断AI 解读

We study the identification and estimation of long-term treatment effects when both experimental and observational data are available. Since the long-term outcome is observed only after a long delay, it is not measured in the experimental data, but only recorded in the observational data. However, both types of data include observations of some short-term outcomes. In this paper, we uniquely tackle the challenge of persistent unmeasured confounders, i.e., some unmeasured…

政策约束下最优动态处理分配规则的估计AI 解读

Many policies involve dynamics in their treatment assignments, where individuals receive sequential interventions over multiple stages. We study estimation of an optimal dynamic treatment regime that guides the optimal treatment assignment for each individual at each stage based on their history. We propose an empirical welfare maximization approach in this dynamic framework, which estimates the optimal dynamic treatment regime using data from an experimental or…

倾向得分处理效应估计方法的模拟比较AI 解读

In observational studies, the recorded treatment assignment is not purely random, but it is influenced by external factors such as patient characteristics, reimbursement policies, and existing guidelines. Therefore, the treatment effect can be estimated only after accounting for confounding factors. Propensity score (PS) methods are a family of methods that is widely used for this purpose. Although they are all based on the estimation of the a posteriori probability of…

使用局部模型的不变因果预测AI 解读

We consider the task of identifying the causal parents of a target variable among a set of candidates from observational data. Our main assumption is that the candidate variables are observed in different environments which may, under certain assumptions, be regarded as interventions on the observed system. We assume a linear relationship between target and candidates, which can be different in each environment with the only restriction that the causal structure is invariant…

异质加性处理效应模型下平均处理效应的估计与推断AI 解读

Randomized experiments are the gold standard for estimating treatment effects, yet network interference challenges the validity of traditional estimators by violating the stable unit treatment value assumption and introducing bias. While cluster randomized experiments mitigate this bias, they encounter limitations in handling network complexity and fail to distinguish between direct and indirect effects. To address these challenges, we develop a design-based asymptotic…

观察性研究中的效应混叠AI 解读

In experimental design, aliasing of effects occurs in fractional factorial experiments, where certain low order factorial effects are indistinguishable from certain high order interactions: low order contrasts may be orthogonal to one another, while their higher order interactions are aliased and not identified. In observational studies, aliasing occurs when certain combinations of covariates -- e.g., time period and various eligibility criteria for treatment -- perfectly…

无需显式无环约束的可扩展变分因果发现AI 解读

Bayesian causal discovery offers the power to quantify epistemic uncertainties among a broad range of structurally diverse causal theories potentially explaining the data, represented in forms of directed acyclic graphs (DAGs). However, existing methods struggle with efficient DAG sampling due to the complex acyclicity constraint. In this study, we propose a scalable Bayesian approach to effectively learn the posterior distribution over causal graphs given observational data…

用归一化流实现后非线性模型的因果发现AI 解读

Post-nonlinear (PNL) causal models stand out as a versatile and adaptable framework for modeling intricate causal relationships. However, accurately capturing the invertibility constraint required in PNL models remains challenging in existing studies. To address this problem, we introduce CAF-PoNo (Causal discovery via Normalizing Flows for Post-Nonlinear models), harnessing the power of the normalizing flows architecture to enforce the crucial invertibility constraint in…

基于潜在获益的干预效应AI 解读

Optimal treatment rules are mappings from individual patient characteristics to tailored treatment assignments that maximize mean outcomes. In this work, we introduce a conditional potential benefit (CPB) metric that measures the expected improvement under an optimally chosen treatment compared to the status quo, within covariate strata. The potential benefit combines (i) the magnitude of the treatment effect, and (ii) the propensity for subjects to naturally select a…

自适应加权随机隔离：网络干扰下因果效应的实验设计AI 解读

Recently, causal inference under interference has gained increasing attention in the literature. In this paper, we focus on randomized designs for estimating the total treatment effect (TTE), defined as the average difference in potential outcomes between fully treated and fully controlled groups. We propose a simple design called weighted random isolation (WRI) along with a restricted difference-in-means estimator (RDIM) for TTE estimation. Additionally, we derive a novel…

用不完全竞争数据拒绝完全竞争假设的统计困难AI 解读

We theoretically prove why statistically rejecting the null hypothesis of perfect competition is challenging, known as a common problem in the literature. We also assess the finite sample performance of the conduct parameter test in homogeneous goods markets, showing that statistical power increases with the number of markets, a larger conduct parameter, and a stronger demand rotation instrument. However, even with a moderate number of markets and five firms, rejecting the…