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Counterfactual and Synthetic Control Method: Causal Inference with Instrumented Principal Component Analysis

反事实与合成控制:利用工具化主成分分析进行因果推断

In this paper, we propose a novel method for causal inference within the framework of counterfactual and synthetic control. Matching forward the generalized synthetic control method, our instrumented principal component analysis method instruments factor loadings with predictive covariates rather than including them as regressors. These instrumented factor loadings exhibit time-varying dynamics, offering a better economic interpretation. Covariates are instrumented through a…

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Group Sequential Testing of a Treatment Effect Using a Surrogate Marker

利用替代指标对处理效应进行群序贯检验

The identification of surrogate markers is motivated by their potential to make decisions sooner about a treatment effect. However, few methods have been developed to actually use a surrogate marker to test for a treatment effect in a future study. Most existing methods consider combining surrogate marker and primary outcome information to test for a treatment effect, rely on fully parametric methods where strict parametric assumptions are made about the relationship between…

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Bounding the probability of causality under ordinal outcomes

有序结果下因果归因概率的界限

The probability of causation (PC) is often used in liability assessments. In a legal context, for example, where a patient suffered the side effect after taking a medication and sued the pharmaceutical company as a result, the value of the PC can help assess the likelihood that the side effect was caused by the medication, in other words, how likely it is that the patient will win the case. Beyond the issue of legal disputes, the PC plays an equally large role when one wants…

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Bridging multiple worlds: multi-marginal optimal transport for causal partial-identification problem

连接多个潜在世界:因果部分识别的多边际最优传输方法

Under the prevalent potential outcome model in causal inference, each unit is associated with multiple potential outcomes but at most one of which is observed, leading to many causal quantities being only partially identified. The inherent missing data issue echoes the multi-marginal optimal transport (MOT) problem, where marginal distributions are known, but how the marginals couple to form the joint distribution is unavailable. In this paper, we cast the causal partial…

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Concentration of a sparse Bayesian model with Horseshoe prior in estimating high-dimensional precision matrix

稀疏贝叶斯 Horseshoe 先验在高维精度矩阵估计中的集中性

Precision matrices are crucial in many fields such as social networks, neuroscience, and economics, representing the edge structure of Gaussian graphical models (GGMs), where a zero in an off-diagonal position of the precision matrix indicates conditional independence between nodes. In high-dimensional settings where the dimension of the precision matrix \( p \) exceeds the sample size \( n \) and the matrix is sparse, methods like graphical Lasso, graphical SCAD, and CLIME…

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Using LASSO for Variable Selection in Exponential Random Graph models

使用LASSO进行指数随机图模型的变量选择

The paper demonstrates the use of LASSO-based estimation in network models. Taking the Exponential Random Graph Model (ERGM) as a flexible and widely used model for network data analysis, the paper focuses on the question of how to specify the (sufficient) statistics, that define the model structure. This includes both, endogenous network statistics (e.g. twostars, triangles, etc.) as well as statistics involving exogenous covariates; on the node as well as on the edge…

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Identifiable causal inference with noisy treatment and no side information

处理变量含噪且无辅助信息时的可识别因果推断

In some causal inference scenarios, the treatment variable is measured inaccurately, for instance in epidemiology or econometrics. Failure to correct for the effect of this measurement error can lead to biased causal effect estimates. Previous research has not studied methods that address this issue from a causal viewpoint while allowing for complex nonlinear dependencies and without assuming access to side information. For such a scenario, this study proposes a model that…

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Identification and multiply robust estimation in causal mediation analysis across principal strata

主分层间因果中介分析的识别与多重稳健估计

We consider assessing causal mediation in the presence of a post-treatment event (examples include noncompliance, a clinical event, or death). We identify natural mediation effects for the entire study population and for each principal stratum characterized by the joint potential values of the post-treatment event. We derive the efficient influence function for each mediation estimand, which motivates a set of multiply robust estimators for inference. The multiply robust…

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How to achieve model-robust inference in stepped wedge trials with model-based methods?

如何用模型方法实现阶梯楔形试验的模型稳健推断?

A stepped wedge design is a unidirectional crossover design where clusters are randomized to distinct treatment sequences. While model-based analysis of stepped wedge designs is standard practice to evaluate treatment effects accounting for clustering and adjusting for covariates, their properties under misspecification have not been systematically explored. In this article, we focus on model-based methods, including linear mixed models and generalized estimating equations…

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Estimation and Inference for Three-Dimensional Panel Data Models

三维面板数据模型的估计与推断

Hierarchical panel data models have recently garnered significant attention. This study contributes to the relevant literature by introducing a novel three-dimensional (3D) hierarchical panel data model, which integrates panel regression with three sets of latent factor structures: one set of global factors and two sets of local factors. Instead of aggregating latent factors from various nodes, as seen in the literature of distributed principal component analysis (PCA), we…

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The First-stage F Test with Many Weak Instruments

大量弱工具变量下的第一阶段 F 检验

A widely adopted approach for detecting weak instruments is to use the first-stage $F$ statistic. While this method was developed with a fixed number of instruments, its performance with many instruments remains insufficiently explored. We show that the first-stage $F$ test exhibits distorted sizes for detecting many weak instruments, regardless of the choice of pretested estimators or Wald tests. These distortions occur due to the inadequate approximation using classical…

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Anytime-Valid Inference for Double/Debiased Machine Learning of Causal Parameters

因果参数双重去偏机器学习的任意时点有效推断

Double (debiased) machine learning (DML) has seen widespread use in recent years for learning causal/structural parameters, in part due to its flexibility and adaptability to high-dimensional nuisance functions as well as its ability to avoid bias from regularization or overfitting. However, the classic double-debiased framework is only valid asymptotically for a predetermined sample size, thus lacking the flexibility of collecting more data if sharper inference is needed,…

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Cross-validation on Extreme Regions

极端区域上的交叉验证

We conduct a non asymptotic study of the Cross Validation (CV) estimate of the generalization risk for learning algorithms dedicated to extreme regions of the covariates space. In this Extreme Value Analysis context, the risk function measures the algorithm's error given that the norm of the input exceeds a high quantile. The main challenge within this framework is the negligible size of the extreme training sample with respect to the full sample size and the necessity to…

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Estimation and Inference for Causal Functions with Multiway Clustered Data

多维聚类数据下因果函数的估计与推断

This paper proposes methods of estimation and uniform inference for a general class of causal functions, such as the conditional average treatment effects and the continuous treatment effects, under multiway clustering. The causal function is identified as a conditional expectation of an adjusted (Neyman-orthogonal) signal that depends on high-dimensional nuisance parameters. We propose a two-step procedure where the first step uses machine learning to estimate the…

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Ensemble Doubly Robust Bayesian Inference via Regression Synthesis

通过回归合成开展集成双重稳健贝叶斯推断

The doubly robust estimator, which models both the propensity score and outcomes, is a popular approach to estimate the average treatment effect in the potential outcome setting. The primary appeal of this estimator is its theoretical property, wherein the estimator achieves consistency as long as either the propensity score or outcomes is correctly specified. In most applications, however, both are misspecified, leading to considerable bias that cannot be checked. In this…

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Weighted Regression with Sybil Networks

女巫网络下的加权回归

In many online domains, Sybil networks -- or cases where a single user assumes multiple identities -- is a pervasive feature. This complicates experiments, as off-the-shelf regression estimators at least assume known network topologies (if not fully independent observations) when Sybil network topologies in practice are often unknown. The literature has exclusively focused on techniques to detect Sybil networks, leading many experimenters to subsequently exclude suspected…

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An MPEC Estimator for the Sequential Search Model

序贯搜寻模型的 MPEC 估计器

This paper proposes a constrained maximum likelihood estimator for sequential search models, using the MPEC (Mathematical Programming with Equilibrium Constraints) approach. This method enhances numerical accuracy while avoiding ad hoc components and errors related to equilibrium conditions. Monte Carlo simulations show that the estimator performs better in small samples, with lower bias and root-mean-squared error, though less effectively in large samples. Despite these…

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Benchmarking Estimators for Natural Experiments: A Novel Dataset and a Doubly Robust Algorithm

自然实验估计器的基准评测:新数据集与双重稳健算法

Estimating the effect of treatments from natural experiments, where treatments are pre-assigned, is an important and well-studied problem. We introduce a novel natural experiment dataset obtained from an early childhood literacy nonprofit. Surprisingly, applying over 20 established estimators to the dataset produces inconsistent results in evaluating the nonprofit's efficacy. To address this, we create a benchmark to evaluate estimator accuracy using synthetic outcomes,…

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Incorporating external data for analyzing randomized clinical trials: A transfer learning approach

利用外部数据分析随机临床试验:迁移学习方法

Randomized clinical trials are the gold standard for analyzing treatment effects, but high costs and ethical concerns can limit recruitment, potentially leading to invalid inferences. Incorporating external trial data with similar characteristics into the analysis using transfer learning appears promising for addressing these issues. In this paper, we present a formal framework for applying transfer learning to the analysis of clinical trials, considering three key…

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Jeffreys-prior penalty for high-dimensional logistic regression: A conjecture about aggregate bias

高维逻辑回归中 Jeffreys 先验惩罚的聚合偏差猜想

Firth (1993, Biometrika) shows that the maximum Jeffreys' prior penalized likelihood estimator in logistic regression has asymptotic bias decreasing with the square of the number of observations when the number of parameters is fixed, which is an order faster than the typical rate from maximum likelihood. The widespread use of that estimator in applied work is supported by the results in Kosmidis and Firth (2021, Biometrika), who show that it takes finite values, even in…

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Extreme Quantile Treatment Effects under Endogeneity: Evaluating Policy Effects for the Most Vulnerable Individuals

内生性下的极端分位数处理效应:评估最弱势群体的政策效果

We introduce a novel method for estimating and conducting inference about extreme quantile treatment effects (QTEs) in the presence of endogeneity. Our approach is applicable to a broad range of empirical research designs, including instrumental variables design and regression discontinuity design, among others. By leveraging regular variation and subsampling, the method ensures robust performance even in extreme tails, where data may be sparse or entirely absent. Simulation…

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A tutorial on panel data analysis using partially observed Markov processes via the R package panelPomp

使用 R 包 panelPomp 分析部分可观测马尔可夫面板过程的教程

The R package panelPomp supports analysis of panel data via a general class of partially observed Markov process models (PanelPOMP). This package tutorial describes how the mathematical concept of a PanelPOMP is represented in the software and demonstrates typical use-cases of panelPomp. Monte Carlo methods used for POMP models require adaptation for PanelPOMP models due to the higher dimensionality of panel data. The package takes advantage of recent advances for PanelPOMP,…

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Multiply-Robust Causal Change Attribution

多重稳健的因果变化归因

Comparing two samples of data, we observe a change in the distribution of an outcome variable. In the presence of multiple explanatory variables, how much of the change can be explained by each possible cause? We develop a new estimation strategy that, given a causal model, combines regression and re-weighting methods to quantify the contribution of each causal mechanism. Our proposed methodology is multiply robust, meaning that it still recovers the target parameter under…

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Co-Developing Causal Graphs with Domain Experts Guided by Weighted FDR-Adjusted p-values

以加权多重检验调整后的 p 值辅助领域专家共建因果图

This paper proposes an approach facilitating co-design of causal graphs between subject matter experts and statistical modellers. Modern causal analysis starting with formulation of causal graphs provides benefits for robust analysis and well-grounded decision support. Moreover, this process can enrich the discovery and planning phase of data science projects. The key premise is that plotting relevant statistical information on a causal graph structure can facilitate an…

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