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随机系数模型的切片 Wasserstein 距离与扩散方法AI 解读

We propose a new minimum-distance estimator for linear random coefficient models. This estimator integrates the recently advanced sliced Wasserstein distance with the nearest neighbor methods, both of which enhance computational efficiency. We demonstrate that the proposed method is consistent in approximating the true distribution. Moreover, our formulation naturally leads to a diffusion process-based algorithm and is closely connected to treatment effect distribution…

从边际结构模型精确模拟纵向数据AI 解读

Simulating longitudinal data from specified marginal structural models is a crucial but challenging task for evaluating causal inference methods and informing study design. While data generation typically proceeds in a fully conditional manner using structural equations according to a temporal ordering, it is difficult to ensure alignment between conditional distributions and the target marginal causal effects, which presents a fundamental challenge. To address this, we…

分数解释型异质处理效应模型中的平均处理效应估计与推断AI 解读

In many practical situations, randomly assigning treatments to subjects is uncommon due to feasibility constraints. For example, economic aid programs and merit-based scholarships are often restricted to those meeting specific income or exam score thresholds. In these scenarios, traditional approaches to estimating treatment effects typically focus solely on observations near the cutoff point, thereby excluding a significant portion of the sample and potentially leading to…

利用主层分层分析受损随机实验AI 解读

Although randomized controlled trials have long been regarded as the ``gold standard'' for evaluating treatment effects, there is no natural prevention from post-treatment events. For example, non-compliance makes the actual treatment different from the assigned treatment, truncation-by-death renders the outcome undefined or ill-defined, and missingness prevents the outcomes from being measured. In this paper, we develop a statistical analysis framework using principal…

无需匹配的目标试验模拟：利用观察数据更高效评估疫苗有效性AI 解读

Real-world vaccine effectiveness has increasingly been studied using matching-based approaches, particularly in observational cohort studies following the target trial emulation framework. Although matching is appealing in its simplicity, it suffers important limitations in terms of clarity of the target estimand and the efficiency or precision with which is it estimated. Scientifically justified causal estimands of vaccine effectiveness may be difficult to define owing to…

用于数字广告边际处理效应估计的多单元实验AI 解读

Randomized experiments with treatment and control groups are an important tool to measure the impacts of interventions. However, in experimental settings with one-sided noncompliance extant empirical approaches may not produce the estimands a decision maker needs to solve the problem of interest. For example, these experimental designs are common in digital advertising settings but typical methods do not yield effects that inform the intensive margin: how many consumers…

右删失事件时间数据的回归型近端因果推断AI 解读

Unmeasured confounding is one of the major concerns in causal inference from observational data. Proximal causal inference (PCI) is an emerging methodological framework to detect and potentially account for confounding bias by carefully leveraging a pair of negative control exposure (NCE) and outcome (NCO) variables, also known as treatment and outcome confounding proxies. Although regression-based PCI is well developed for binary and continuous outcomes, analogous PCI…

用于实验设计的合成控制AI 解读

This article studies experimental design in settings where the experimental units are large aggregate entities (e.g., markets), and only one or a small number of units can be exposed to the treatment. In such settings, randomization of the treatment may result in treated and control groups with very different characteristics at baseline, inducing biases. We propose a variety of experimental non-randomized synthetic control designs (Abadie, Diamond and Hainmueller, 2010,…

大量弱工具变量与处理效应异质性下的推断AI 解读

This paper considers inference in a linear instrumental variable regression model with many potentially weak instruments, in the presence of heterogeneous treatment effects. I first show that existing test procedures, including those that are robust to either weak instruments or heterogeneous treatment effects, can be arbitrarily oversized. I propose a novel and valid test based on a score statistic and a ``leave-three-out" variance estimator. In the presence of…

通过结构边际化与自回归因果顺序实现贝叶斯因果推断AI 解读

The traditional two-stage approach to causal inference first identifies a single causal model (or equivalence class of models), which is then used to answer causal queries. However, this neglects any epistemic model uncertainty. In contrast, Bayesian causal inference does incorporate epistemic uncertainty into query estimates via Bayesian marginalisation (posterior averaging) over all causal models. While principled, this marginalisation over entire causal models, i.e., both…

动态离散与连续选择模型：识别与条件选择概率估计AI 解读

This paper develops a general framework for dynamic models in which individuals simultaneously make both discrete and continuous choices. The framework incorporates a wide range of unobserved heterogeneity. I show that such models are nonparametrically identified. Based on constructive identification arguments, I build a novel two-step estimation method in the lineage of Hotz and Miller (1993) and Arcidiacono and Miller (2011) but extended to simultaneous discrete-continuous…

地球观测与机器学习用于因果推断的范围综述：贫困地理研究的启示AI 解读

Earth observation (EO) data such as satellite imagery can have far-reaching impacts on our understanding of the geography of poverty, especially when coupled with machine learning (ML) and computer vision. Early research used computer vision to predict living conditions in areas with limited data, but recent studies increasingly focus on causal analysis. Despite this shift, the use of EO-ML methods for causal inference lacks thorough documentation, and best practices are…

映射至目标试验的干预效应：高维中介分析中的因果机器学习AI 解读

Causal mediation analysis examines causal pathways linking exposures to disease. The estimation of interventional effects, which are mediation estimands that overcome certain identifiability problems of natural effects, has been advanced through causal machine learning methods, particularly for high-dimensional mediators. Recently, it has been proposed interventional effects can be defined in each study by mapping to a target trial assessing specific hypothetical mediator…

双重稳健 t 统计量能够承受多弱的重叠？AI 解读

In the presence of sufficiently weak overlap, it is known that no regular root-n-consistent estimators exist and standard estimators may fail to be asymptotically normal. This paper shows that a thresholded version of the standard doubly robust estimator is asymptotically normal with well-calibrated Wald confidence intervals even when constructed using nonparametric estimates of the propensity score and conditional mean outcome. The analysis implies a cost of weak overlap in…

检测处理效应异质性时可忽略组内相关系数的整群随机试验AI 解读

Accurately estimating the intra-class correlation coefficient (ICC) is crucial for adequately powering clustered randomized trials (CRTs). Challenges arise due to limited prior data on the specific outcome within the target population, making accurate ICC estimation difficult. Furthermore, ICC can vary significantly across studies, even for the same outcome, influenced by factors like study design, participant characteristics, and the specific intervention. Power…

具有多个异质结局的基因组数据因果推断AI 解读

With the evolution of single-cell RNA sequencing techniques into a standard approach in genomics, it has become possible to conduct cohort-level causal inferences based on single-cell-level measurements. However, the individual gene expression levels of interest are not directly observable; instead, only repeated proxy measurements from each individual's cells are available, providing a derived outcome to estimate the underlying outcome for each of many genes. In this paper,…

分类处理的微随机试验：因果效应估计与样本量计算AI 解读

Micro-randomized trials (MRTs) are widely used to assess the marginal and moderated effect of mobile health (mHealth) treatments delivered via mobile devices. In many applications, the mHealth treatments are categorical with multiple levels such as different types of message contents, but existing analysis and sample size calculation methods for MRTs only focus on binary treatment options (i.e., prompt vs. no prompt). We extended the causal excursion effect definition and…

贝叶斯多元逻辑模型中的因子预训练AI 解读

This article focuses on inference in logistic regression for high-dimensional binary outcomes. A popular approach induces dependence across the outcomes by including latent factors in the linear predictor. Bayesian approaches are useful for characterizing uncertainty in inferring the regression coefficients, factors and loadings, while also incorporating hierarchical and shrinkage structure. However, Markov chain Monte Carlo algorithms for posterior computation face…

利用替代指标信息进行高效检验AI 解读

In modern clinical trials, there is immense pressure to use surrogate markers in place of an expensive or long-term primary outcome to make more timely decisions about treatment effectiveness. However, using a surrogate marker to test for a treatment effect can be difficult and controversial. Existing methods tend to either rely on fully parametric methods where strict assumptions are made about the relationship between the surrogate and the outcome, or assume the surrogate…

因果有向无环图的摘要化：完整版本AI 解读

Causal inference aids researchers in discovering cause-and-effect relationships, leading to scientific insights. Accurate causal estimation requires identifying confounding variables to avoid false discoveries. Pearl's causal model uses causal DAGs to identify confounding variables, but incorrect DAGs can lead to unreliable causal conclusions. However, for high dimensional data, the causal DAGs are often complex beyond human verifiability. Graph summarization is a logical…

衰减随机缺失框架：部分标注数据中的模型双重稳健因果推断AI 解读

In modern large-scale observational studies, data collection constraints often result in partially labeled datasets, posing challenges for reliable causal inference, especially due to potential labeling bias and relatively small size of the labeled data. This paper introduces a decaying missing-at-random (decaying MAR) framework and associated approaches for doubly robust causal inference on treatment effects in such semi-supervised (SS) settings. This simultaneously…

结局均值函数一般半参数约束下的有效估计与数据融合AI 解读

We provide a novel characterization of semiparametric efficiency in a generic supervised learning setting where the outcome mean function -- defined as the conditional expectation of the outcome of interest given the other observed variables -- is restricted to lie in some known semiparametric function class. The primary motivation is causal inference where a researcher running a randomized controlled trial often has access to an auxiliary observational dataset that is…

利用偏度准则处理因果发现中的异方差噪声AI 解读

Real-world data often violates the equal-variance assumption (homoscedasticity), making it essential to account for heteroscedastic noise in causal discovery. In this work, we explore heteroscedastic symmetric noise models (HSNMs), where the effect $Y$ is modeled as $Y = f(X) + σ(X)N$, with $X$ as the cause and $N$ as independent noise following a symmetric distribution. We introduce a novel criterion for identifying HSNMs based on the skewness of the score (i.e., the…

将推断推广至目标总体时应对正值性违背AI 解读

Enhancing the external validity of trial results is essential for their applicability to real-world populations. However, violations of the positivity assumption can limit both the generalizability and transportability of findings. To address positivity violations in estimating the average treatment effect for a target population, we propose a framework that integrates characterizing the underrepresented group and performing sensitivity analysis for inference in the original…