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Sharp Bounds for Continuous-Valued Treatment Effects with Unobserved Confounders

存在未观测混杂时连续处理效应的锐界

In causal inference, treatment effects are typically estimated under the ignorability, or unconfoundedness, assumption, which is often unrealistic in observational data. By relaxing this assumption and conducting a sensitivity analysis, we introduce novel bounds and derive confidence intervals for the Average Potential Outcome (APO) - a standard metric for evaluating continuous-valued treatment or exposure effects. We demonstrate that these bounds are sharp under a…

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A note on the properties of the confidence set for the local average treatment effect obtained by inverting the score test

反演得分检验得到的局部平均处理效应置信集性质

We study the properties of the score confidence set for the local average treatment effect in non and semiparametric instrumental variable models. This confidence set is constructed by inverting a score test based on an estimate of the nonparametric influence function for the estimand, and is known to be uniformly valid in models that allow for arbitrarily weak instruments; because of this, the confidence set can have infinite diameter at some laws. We characterize the six…

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Conditional Triple Difference-in-Differences

条件三重差分法

Triple difference-in-differences designs are widely used to estimate causal effects in empirical work. Surveying the literature, we find that most applications include controls. We show that this standard practice is generally biased for the target causal estimand when covariate distributions differ across groups. To address this, we propose identifying a causal estimand by fixing the covariate distribution to that of one group. We then develop a double-robust estimator and…

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Efficiency of QMLE for dynamic panel data models with interactive effects

含交互效应动态面板模型的准极大似然估计效率

This paper studies the problem of efficient estimation of panel data models in the presence of an increasing number of incidental parameters. We formulate the dynamic panel as a simultaneous equations system, and derive the efficiency bound under the normality assumption. We then show that the Gaussian quasi-maximum likelihood estimator (QMLE) applied to the system achieves the normality efficiency bound without the normality assumption. Comparison of QMLE with the fixed…

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Estimating the Number of Components in Panel Data Finite Mixture Regression Models with an Application to Production Function Heterogeneity

面板有限混合回归的成分数估计及生产函数异质性应用

This paper develops statistical methods for determining the number of components in panel data finite mixture regression models with regression errors independently distributed as normal or more flexible normal mixtures. We analyze the asymptotic properties of the likelihood ratio test (LRT) and information criteria (AIC and BIC) for model selection in both conditionally independent and dynamic panel settings. Unlike cross-sectional normal mixture models, we show that panel…

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Causal effects on non-terminal event time with application to antibiotic usage and future resistance

非终末事件时间的因果效应:抗生素使用与未来耐药性

Comparing future antibiotic resistance levels resulting from different antibiotic treatments is challenging because some patients may survive only under one of the antibiotic treatments. We embed this problem within a semi-competing risks approach to study the causal effect on resistant infection, treated as a non-terminal event time. We argue that existing principal stratification estimands for such problems exclude patients for whom a causal effect is well-defined and is…

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Fisher's Randomization Test for Causality with General Types of Treatments

适用于一般处理类型的 Fisher 因果随机化检验

We extend Fisher's randomization test (FRT) to test conditional independence between observed outcomes and treatments given covariates in both randomized experiments and observational studies, with no restriction on the variable type of treatments. Under a generalized unconfoundedness assumption, we provide causal identification for this hypothesis. Our approach requires neither the no-interference nor the positive overlap assumption, making it a widely applicable tool for…

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Longitudinal weighted and trimmed treatment effects with flip interventions

基于翻转干预的纵向加权与修剪处理效应

Weighting and trimming are popular methods for addressing positivity violations in causal inference. While well-studied with single-timepoint data, standard methods do not easily generalize to address non-baseline positivity violations in longitudinal data, and remain vulnerable to such violations. In this paper, we extend weighting and trimming to longitudinal data via stochastic ``flip'' interventions, which maintain the treatment status of subjects who would have received…

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Fragility in Average Treatment Effect on the Treated under Limited Covariate Support

协变量支持有限时已处理者平均处理效应的脆弱性

This paper studies the identification of the average treatment effect on the treated (ATT) under unconfoundedness when covariate overlap is partial. A formal diagnostic is proposed to characterize empirical support -- the subset of the covariate space where ATT is point-identified due to the presence of comparable untreated units. Where support is absent, standard estimators remain computable but cease to identify meaningful causal parameters. A general sensitivity framework…

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Quantifying Treatment Effects: Estimating Risk Ratios in Causal Inference

量化处理效应:因果推断中的风险比估计

Randomized Controlled Trials (RCT) are the current gold standards to empirically measure the effect of a new drug. However, they may be of limited size and resorting to complementary non-randomized data, referred to as observational, is promising, as additional sources of evidence. In both RCT and observational data, the Risk Difference (RD) is often used to characterize the effect of a drug. Additionally, medical guidelines recommend to also report the Risk Ratio (RR),…

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Distinguishing Cause from Effect with Causal Velocity Models

利用因果速度模型区分原因与结果

Bivariate structural causal models (SCM) are often used to infer causal direction by examining their goodness-of-fit under restricted model classes. In this paper, we describe a parametrization of bivariate SCMs in terms of a causal velocity by viewing the cause variable as time in a dynamical system. The velocity implicitly defines counterfactual curves via the solution of initial value problems where the observation specifies the initial condition. Using tools from measure…

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A structural nested rate model for estimating the effects of time-varying exposure on recurrent event outcomes in the presence of death

死亡存在时估计时变暴露对复发事件影响的结构嵌套率模型

Assessing the causal effect of time-varying exposures on recurrent event processes is challenging in the presence of a terminating event. Our objective is to estimate both the short-term and delayed marginal causal effects of exposures on recurrent events while addressing the bias of a potentially correlated terminal event. Existing estimators based on marginal structural models and proportional rate models are unsuitable for estimating delayed marginal causal effects for…

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A Randomization-Based Method for Evaluating Time-Varying Treatment Effects

评价时变处理效应的随机化方法

Tests for paired censored outcomes have been extensively studied, with some justified in the context of randomization-based inference. These tests are primarily designed to detect an overall treatment effect across the entire follow-up period, providing limited insight into when the effect manifests and how it changes over time. In this article, we introduce new randomization-based tests for paired censored outcomes that enable both time-specific and long-term analysis of a…

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Forests for Differences: Robust Causal Inference Beyond Parametric DiD

用于双重差分的森林:超越参数模型的因果推断

This paper introduces the Difference-in-Differences Bayesian Causal Forest (DiD-BCF), a novel non-parametric model addressing key challenges in DiD estimation, such as staggered adoption and heterogeneous treatment effects. DiD-BCF provides a unified framework for estimating Average (ATE), Group-Average (GATE), and Conditional Average Treatment Effects (CATE). A core innovation, its Parallel Trends Assumption (PTA)-based reparameterization, enhances estimation accuracy and…

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Bayesian inference for dynamic spatial quantile models with interactive effects

含交互效应的动态空间分位数模型的贝叶斯推断

With the rapid advancement of information technology and data collection systems, large-scale spatial panel data presents new methodological and computational challenges. This paper introduces a dynamic spatial panel quantile model that incorporates unobserved heterogeneity. The proposed model captures the dynamic structure of panel data, high-dimensional cross-sectional dependence, and allows for heterogeneous regression coefficients. To estimate the model, we propose a…

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Economic and Policy Uncertainties and Firm Value: The Case of Consumer Durable Goods

经济与政策不确定性和企业价值:美国耐用品生产商

The objective of this study is to analyze the response of firm value, represented by the Tobin's Q (Q) for a group of twelve U.S. durable goods producers to uncertainties in the US Economy. The results, based on an estimated panel quantile regressions (PQR) and panel vector autoregressive MIDAS model (PVM), show that Q for these firms reacts negatively to the positive shocks to the current ratio, and debt-to-asset ratio and positively to operating income after depreciation…

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Individual Treatment Effect: Prediction Intervals and Sharp Bounds

个体处理效应的预测区间与锐界

Individual treatment effect (ITE) is often regarded as the ideal target of inference in causal analyses and has been the focus of several recent studies. In this paper, we describe the intrinsic limits regarding what can be learned concerning ITEs given data from large randomized experiments. We consider when a valid prediction interval for the ITE is informative and when it can be bounded away from zero. The joint distribution over potential outcomes is only partially…

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Integrating tumor burden with survival outcome for treatment effect evaluation in oncology trials

结合肿瘤负荷与生存结局评价肿瘤试验处理效应

In early-phase cancer clinical trials, the limited availability of data presents significant challenges in developing a framework to efficiently quantify treatment effectiveness. To address this, we propose a novel utility-based Bayesian approach for assessing treatment effects in these trials, where data scarcity is a major concern. Our approach synthesizes tumor burden, a key biomarker for evaluating patient response to oncology treatments, and survival outcome, a widely…

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Using Forests in Multivariate Regression Discontinuity Designs

多评分断点回归设计中的森林方法

We discuss estimation and inference of conditional treatment effects in regression discontinuity (RD) designs with multiple scores. In addition to local linear regressions and the minimax-optimal estimator more recently proposed by Imbens and Wager (2019), we argue that two variants of random forests, honest regression forests and local linear forests, should be added to the toolkit of applied researchers working with multivariate RD designs; their validity follows from…

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Debiased regression adjustment in completely randomized experiments with moderately high-dimensional covariates

中等高维协变量下完全随机实验的去偏回归调整

Completely randomized experiment is the gold standard for causal inference. When the covariate information for each experimental candidate is available, one typical way is to include them in covariate adjustments for more accurate treatment effect estimation. In this paper, we investigate this problem under the randomization-based framework, i.e., that the covariates and potential outcomes of all experimental candidates are assumed as deterministic quantities and the…

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Quantile-Optimal Policy Learning under Unmeasured Confounding

未观测混杂下的分位数最优政策学习

We study quantile-optimal policy learning where the goal is to find a policy whose reward distribution has the largest $α$-quantile for some $α\in (0, 1)$. We focus on the offline setting whose generating process involves unobserved confounders. Such a problem suffers from three main challenges: (i) nonlinearity of the quantile objective as a functional of the reward distribution, (ii) unobserved confounding issue, and (iii) insufficient coverage of the offline dataset. To…

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Structure-agnostic Optimality of Doubly Robust Learning for Treatment Effect Estimation

处理效应估计中双重稳健学习的结构无关最优性

Average treatment effect estimation is the most central problem in causal inference with application to numerous disciplines. While many estimation strategies have been proposed in the literature, the statistical optimality of these methods has still remained an open area of investigation, especially in regimes where these methods do not achieve parametric rates. In this paper, we adopt the recently introduced structure-agnostic framework of statistical lower bounds, which…

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Automatic Doubly Robust Forests

自动双重稳健随机森林

This paper proposes the automatic Doubly Robust Random Forest (DRRF) algorithm for estimating the conditional expectation of a moment functional in the presence of high-dimensional nuisance functions. DRRF extends the automatic debiasing framework based on the Riesz representer to the conditional setting and enables nonparametric, forest-based estimation (Athey et al., 2019; Oprescu et al., 2019). In contrast to existing methods, DRRF does not require prior knowledge of the…

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Practically significant differences between conditional distribution functions

条件分布函数之间具有实际意义的差异

In the framework of semiparametric distribution regression, we consider the problem of comparing the conditional distribution functions corresponding to two samples. In contrast to testing for exact equality, we are interested in the (null) hypothesis that the $L^2$ distance between the conditional distribution functions does not exceed a certain threshold in absolute value. The consideration of these hypotheses is motivated by the observation that in applications, it is…

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