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ProCause: Generating Counterfactual Outcomes to Evaluate Prescriptive Process Monitoring Methods

ProCause:生成反事实结果以评估处方式流程监控方法

Prescriptive Process Monitoring (PresPM) is the subfield of Process Mining that focuses on optimizing processes through real-time interventions based on event log data. Evaluating PresPM methods is challenging due to the lack of ground-truth outcomes for all intervention actions in datasets. A generative deep learning approach from the field of Causal Inference (CI), RealCause, has been commonly used to estimate the outcomes for proposed intervention actions to evaluate a…

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Causal inference and racial bias in policing: New estimands and the importance of mobility data

警务种族偏见的因果推断:新目标参数与流动数据的重要性

Studying racial bias in policing is a critically important problem, but one that comes with a number of inherent difficulties due to the nature of the available data. In this manuscript we tackle multiple key issues in the causal analysis of racial bias in policing. First, we formalize race and place policing, the idea that individuals of one race are policed differently when they are in neighborhoods primarily made up of individuals of other races. We develop an estimand to…

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Statistical Performance Guarantee for Subgroup Identification with Generic Machine Learning

通用机器学习子群识别的统计性能保证

Across a wide array of disciplines, many researchers use machine learning (ML) algorithms to identify a subgroup of individuals who are likely to benefit from a treatment the most (``exceptional responders'') or those who are harmed by it. A common approach to this subgroup identification problem consists of two steps. First, researchers estimate the conditional average treatment effect (CATE) using an ML algorithm. Next, they use the estimated CATE to select those…

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Semiparametric model averaging for high-dimensional quantile regression with nonignorable nonresponse

不可忽略缺失下高维分位数回归的半参数模型平均

Model averaging has demonstrated superior performance for ensemble forecasting in high-dimensional framework, its extension to incomplete datasets remains a critical but underexplored challenge. Moreover, identifying the parsimonious model through averaging procedure in quantile regression demands urgent methodological innovation. In this paper, we propose a novel model averaging method for high-dimensional quantile regression with nonignorable missingness. The idea is to…

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Root-n-consistent Conditional ML estimation of dynamic panel logit models with fixed effects

固定效应动态面板 Logit 模型的根号 n 一致条件极大似然估计

In this paper we first propose a root-n-consistent Conditional Maximum Likelihood (CML) estimator for all the common parameters in the panel logit AR(p) model with strictly exogenous covariates and fixed effects. Our CML estimator (CMLE) converges in probability faster and is more easily computed than the kernel-weighted CMLE of Honoré and Kyriazidou (2000). Next, we propose a root-n-consistent CMLE for the coefficients of the exogenous covariates only. We also discuss new…

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An adaptive design for optimizing treatment assignment in randomized clinical trials

优化随机临床试验处理分配的自适应设计

The treatment assignment mechanism in a randomized clinical trial can be optimized for statistical efficiency within a specified class of randomization mechanisms. Optimal designs of this type have been characterized in terms of the variances of potential outcomes conditional on baseline covariates. Approximating these optimal designs requires information about the conditional variance functions, which is often unavailable or unreliable at the design stage. As a practical…

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Signal Lasso with Non-Convex Penalties for Efficient Network Reconstruction and Topology Inference

非凸惩罚信号套索用于高效网络重构与拓扑推断

Inferring network structures remains an interesting question for its importance on the understanding and controlling collective dynamics of complex systems. The existing shrinking methods such as Lasso-type estimation can not suitably reveal such property. A new method recently suggested, called by {\it signal lasso} (or its updating version: adaptive signal lasso) was proposed to solve the network reconstruction problem, where the signal parameter can be shrunk to either 0…

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Multiply Robust Inference of Average Treatment Effects by High-dimensional Empirical Likelihood

利用高维经验似然进行平均处理效应的多重稳健推断

In this paper, we develop a multiply robust inference procedure of the average treatment effect (ATE) for data with high-dimensional covariates. We consider the case where it is difficult to correctly specify a single parametric model for the propensity scores (PS). For example, the target population is formed from heterogeneous sources with different treatment assignment mechanisms. We propose a novel high-dimensional empirical likelihood weighting method under soft…

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Considerations for Estimating Causal Effects of Informatively Timed Treatments

具有信息性处理时点的因果效应估计

Epidemiological studies are often concerned with estimating causal effects of a sequence of treatment decisions on survival outcomes. In many settings, treatment decisions do not occur at fixed, pre-specified followup times. Rather, timing varies across subjects in ways that may be informative of subsequent treatment decisions and potential outcomes. Awareness of the issue and its potential solutions is lacking in the literature, which motivate this work. Here, we formalize…

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Treatment effects at the margin: Everyone is marginal

边际上的处理效应:每个人都处于边际

This paper develops a framework for identifying treatment effects when a policy simultaneously alters both the incentive to participate and the outcome of interest -- such as hiring decisions and wages in response to employment subsidies; or working decisions and wages in response to job trainings. This framework was inspired by my PhD project on a Belgian reform that subsidised first-time hiring, inducing entry by marginal firms yet meanwhile changing the wages they pay.…

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Discovering Heterogeneous Treatment Effects in Regression Discontinuity Designs

回归不连续设计中的异质性处理效应发现

The paper proposes a causal supervised machine learning algorithm to uncover treatment effect heterogeneity in sharp and fuzzy regression discontinuity (RD) designs. We develop a criterion for building an honest ``regression discontinuity tree'', where each leaf contains the RD estimate of a treatment conditional on the values of some pre-treatment covariates. It is a priori unknown which covariates are relevant for capturing treatment effect heterogeneity, and it is the…

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Change Point Detection on A Separable Model for Dynamic Networks

动态网络可分离模型的变点检测

This paper studies the unsupervised change point detection problem in time series of networks using the Separable Temporal Exponential-family Random Graph Model (STERGM). Inherently, dynamic network patterns are complex due to dyadic and temporal dependence, and change points detection can identify the discrepancies in the underlying data generating processes to facilitate downstream analysis. In particular, the STERGM that utilizes network statistics and nodal attributes to…

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Doubly robust estimation and sensitivity analysis with outcomes truncated by death in multi-arm clinical trials

多组临床试验中死亡截断结局的双重稳健估计与敏感性分析

In clinical trials, the observation of participant outcomes may frequently be hindered by death, leading to ambiguity in defining a scientifically meaningful final outcome for those who die. Principal stratification methods are valuable tools for addressing the average causal effect among always-survivors, i.e., the average treatment effect among a subpopulation defined as those who would survive regardless of treatment assignment. Although robust methods for the…

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Inference on Nonlinear Counterfactual Functionals under a Multiplicative IV Model

乘法工具变量模型下非线性反事实泛函的推断

Instrumental variable (IV) methods play a central role in causal inference, particularly in settings where treatment assignment is confounded by unobserved variables. IV methods have been extensively developed in recent years and applied across diverse domains, from economics to epidemiology. In this work, we study the recently introduced multiplicative IV (MIV) model and demonstrate its utility for causal inference beyond the average treatment effect. In particular, we show…

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Causal machine learning methods and use of cross-fitting in settings with high-dimensional confounding

高维混杂下的因果机器学习方法与交叉拟合

Observational epidemiological studies commonly seek to estimate the causal effect of an exposure on an outcome. Adjustment for potential confounding bias in modern studies is challenging due to the presence of high-dimensional confounding, which occurs when there are many confounders relative to sample size or complex relationships between continuous confounders and exposure and outcome. Doubly robust methods such as Augmented Inverse Probability Weighting (AIPW) and…

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When Is Causal Inference Possible? A Statistical Test for Unmeasured Confounding

何时可以进行因果推断?未测量混杂的统计检验

This paper clarifies a fundamental difference between causal inference and traditional statistical inference by formalizing a mathematical distinction between their respective parameters. We connect two major approaches to causal inference, the potential outcomes framework and causal structure graphs, which are typically studied separately. While the unconfoundedness assumption in the potential outcomes framework cannot be assessed from an observational dataset alone, causal…

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HAL-Based Plug-in Estimation with Pointwise Asymptotic Normality of the Causal Dose-Response Curve

基于 HAL 的因果剂量反应曲线插件估计与逐点渐近正态性

Estimating and obtaining reliable inference for the marginally adjusted causal dose-response curve for continuous treatments without relying on parametric assumptions is a well-known statistical challenge. Parametric models risk introducing significant bias through model misspecification, compromising the accurate representation of the underlying data and dose-response relationship. On the other hand, nonparametric models face difficulties as the dose-response curve is not…

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Inference on Partially Identified Parameters with Separable Nuisance Parameters: a Two-Stage Method

可分离辅助参数下部分识别参数的两阶段推断

This paper develops a two-stage method for inference on partially identified parameters in moment inequality models with separable nuisance parameters. In the first stage, the nuisance parameters are estimated separately, and in the second stage, the identified set for the parameters of interest is constructed using a refined chi-squared test with variance correction that accounts for the first-stage estimation error. We establish the asymptotic validity of the proposed…

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A mixture logistic model for panel data with a Markov structure

具有马尔可夫结构的面板数据混合逻辑回归模型

In this study, we propose a mixture logistic regression model with a Markov structure, and consider the estimation of model parameters using maximum likelihood estimation. We also provide a forward type variable selection algorithm to choose the important explanatory variables to reduce the number of parameters in the proposed model.

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Inspection-Guided Randomization: A Flexible and Transparent Restricted Randomization Framework for Better Experimental Design

检查引导随机化:灵活透明的受限随机化实验设计框架

Randomized experiments are considered the gold standard for estimating causal effects. However, out of the set of possible randomized assignments, some may be likely to produce poor effect estimates and misleading conclusions. Restricted randomization is an experimental design strategy that filters out undesirable treatment assignments, but its application has primarily been limited to ensuring covariate balance in two-arm studies where the target estimand is the average…

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Estimating the average treatment effect in cluster-randomized trials with misclassified outcomes and non-random validation subsets

结局误分类与非随机验证子集下整群随机试验的平均处理效应估计

Randomized trials are viewed as the benchmark for assessing causal effects of treatments on outcomes of interest. Nonetheless, challenges such as measurement error can undermine the standard causal assumptions for randomized trials. In ASPIRE, a cluster-randomized trial, pediatric primary care clinics were assigned to one of two treatments aimed at promoting clinician delivery of a secure firearm program to parents during well-child visits. A key outcome of interest is thus…

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Matching-Based Nonparametric Estimation of Group Average Treatment Effects

基于匹配的组平均处理效应非参数估计

Heterogeneous treatment effects, which vary according to individual covariates, are crucial in fields such as personalized medicine and tailored treatment strategies. In many applications, rather than considering the heterogeneity induced by all covariates, practitioners focus on a few key covariates to develop tailored treatment decisions. Based on this, we aim to estimate the group average treatment effects (GATEs), which represent heterogeneous treatment effects across…

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Causal Inference in Longitudinal Data under Unknown Interference

未知干扰结构下纵向数据的因果推断

In longitudinal studies where units are embedded in space or a social network, interference may arise, meaning that a unit's outcome can depend on treatment histories of others. The presence of interference poses significant challenges for causal inference, particularly when the interference structure -- how a unit's outcome responds to others' influences -- is complex, heterogeneous, and unknown to researchers. This paper develops a general framework for identifying and…

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Causal Effect Identification and Inference with Endogenous Exposures and a Light-tailed Error

内生暴露与轻尾误差下的因果效应识别和推断

Endogeneity poses significant challenges in causal inference across various research domains. This paper proposes a novel approach to identify and estimate causal effects in the presence of endogeneity. We consider a structural equation with endogenous exposures and an additive error term. Assuming the light-tailedness of the error term, we show that the causal effect can be identified by contrasting extreme conditional quantiles of the outcome given the exposures. Unlike…

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