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When Treatments Spill Over: A Neural Framework for Spatiotemporal Causal Effect Estimation

当处理发生溢出:时空因果效应估计的神经网络框架

Real-world public health policies are often enacted by local jurisdictions, but their effects can ripple through connected populations. For causal evaluation, this creates a difficult spatiotemporal problem: intermittent policy updates create path-level treatments, and because spillover depends on neighboring treatment paths along with the focal-unit's own history, controlling time-varying confounding requires high-dimensional, multimodal information from both sources. To…

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Eigenvalue-Decomposition Cost Denoising for Predict-then-Optimize

Predict-then-optimize methods learn a mapping from features to unknown edge costs. They then solve the shortest-path problem on the predicted costs. We study a feature-free alternative for the case where the decision-maker observes many noisy cost vectors on a fixed network. The cost vectors are denoised by an eigenvalue decomposition (PCA) of their covariance matrix. Dijkstra's algorithm then runs on the result. We test this on the $5\times5$ grid of \citet{elmachtoub2022},…

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Rate-Based Causal Discovery for Heavy-Tailed Models

重尾模型中的基于比率的因果发现

In many complex systems, such as river networks and financial markets, extreme events propagate from causes to their effects, and the largest observations carry the most information about the underlying causal structure. Existing methods for causal discovery in extremes, however, are tailored to specific mechanisms, such as linear or max-linear models. This work develops causal discovery for heavy-tailed homogeneous structural causal models, a flexible class that contains…

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Identification and Estimation of Treatment Effects from Network Data with Confounded Social Links

社会网络数据中处理效应的识别与估计:当社会连接存在混杂时

In observational network data, the adoption of a treatment and the formation of social ties often depend on the same characteristics that affect outcomes. We propose a generalized propensity score for each unit's effective treatment, built from a model for treatment assignment and a dyadic model for network formation, which may include latent node heterogeneity. The score is marginalized over the network given covariates rather than conditioned on the realized network, and…

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Inference for Heterogeneous Graphical Models using Doubly High-Dimensional Linear-Mixed Models

双重高维线性混合模型下异质图模型的推断

Inferring the structure of population-level functional connectivity networks from multi-subject functional magnetic resonance imaging data is essential for understanding the connectivity patterns underlying cognitive and behavioral functions. Graphical models provide a formal statistical framework for inferring the graph structure. However, the multi-level nature of functional magnetic resonance imaging data---where each level corresponds, for instance, to a…

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Simple Standard Errors for Complicated (Quasi-)Experimental Designs

复杂(准)实验设计下的简单标准误

We develop standard errors for estimates of causal effects in settings where the distribution of treatment exposures is known but potentially exhibits complicated dependence patterns across units. Such dependence arises, for example, in settings with spillovers/interference across units or when the treatment assignment is spatially correlated. Our variance estimator generalizes several properties of the Neyman variance estimator for completely randomized experiments to…

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Robust Inference for Dyadic Data with Spatially Dependent Nodes

We develop inference for complete dyadic samples with spatial dependence governed by geographic distances between nodes, covering settings beyond the scope of existing dyadic inference theory. We propose spatial variance and corrected block jackknife estimators consistent in nondegenerate and degenerate Gaussian cases. Under degeneracy, spatial subsampling consistently estimates possibly non-Gaussian limits. Combining the jackknife with subsampling yields the max…

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Network Experiments with Edge Treatments and Node Outcomes

边处理与节点结果的网络实验

We present a methodology for analyzing node-level outcomes while experimenting with edge-level treatments in a population connected by an undirected graph. Under our design, nodes are randomly assigned to test or control, and each edge inherits the treatment of its endpoints, with conflicts resolved by randomization. We use each node's assigned status as an instrument for its treatment exposure. We show that the Wald estimator is consistent for the global average treatment…

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Sharp bounds for within-household encouragement designs with interference

Experiments with spillovers create incentives for strategic behavior: when one household member's treatment can affect another, take-up decisions become interdependent. We propose an instrumental-variables framework grounded in game theory, in which take-up is a Nash equilibrium among a small number of agents, and all variables are discrete. Under minimal assumptions, without specifying how equilibria are selected, we derive sharp non-parametric bounds for direct, indirect,…

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Network inference for SDEs with diverging dimension under small noise

小噪声下维度发散的网络随机微分方程推断

We consider inference for network stochastic differential equations in a small-noise, high-dimensional regime, where the diffusion coefficient vanishes with $\ep\to0$ while the network size and parameter dimension may diverge. We develop a minimum-distance estimation framework based on a deterministic measurement model that may omit nuisance terms in the drift, and derive a non-asymptotic error bound decomposing the estimation error into stochastic fluctuation, nuisance…

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Optimal Community Recovery by Spectrally Initialized Variational EM in General Stochastic Block Models

一般随机块模型中谱初始化变分 EM 的最优社区恢复

We prove a Chernoff-exponent guarantee for the output of spectrally initialized batch variational EM after a prescribed iteration budget, without assuming global maximization of its variational objective. The iteration repeatedly estimates the entire block probability matrix and community proportions from the same sparse graph. We consider a fixed number of communities with proportions bounded away from zero and fixed, positive, distinct connectivity profiles; neither…

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Direct estimation and inference of differential Granger causality between two high-dimensional time series

Comparing dependence structures between two related multivariate time series is of fundamental interest in many scientific applications, where changes may occur in both directed temporal interactions and contemporaneous connectivity. Modeling each time series by a vector autoregressive (VAR) model, we propose a new framework for estimation and inference of differential Granger causality (DiffGC) and differential network (DiffNet) structures in high dimensions. The proposed…

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Partial Identification under Imperfect Measurement: A Distributionally Robust Approach

不完美测量下的部分识别:分布鲁棒方法

Imperfect measurements allow different underlying distributions to generate the same observations. Restrictions linking unobserved components can make it difficult to characterize all compatible distributions and compute the resulting range of parameter values. We ask how to construct computable parameter bounds and tighten them without additional data or stronger assumptions. We develop a general framework for partial identification under imperfect measurement based on…

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Network-Constrained Matching and Randomization-Based Inference for Causal Effects

网络约束匹配与因果效应的随机化推断

Matching is widely used to mimic randomized experiments by forming matched sets in which treated and control units differ only randomly with respect to observed covariates. However, when the study population consists of interconnected units from a single network or a small number of networks, matching solely on observed covariates may produce matched units that are more closely connected in the network than would occur by chance. This increased network proximity within…

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A Path-Dependent Agent-Based Microsimulation of Crime and Violence Reduction Policy Portfolios in Bolivia: Survey Calibration, Adaptive Emulator Ensembles, Global Sensitivity, Tempered MCMC, and Multi-Objective Policy Analysis

玻利维亚犯罪与暴力治理政策组合的路径依赖主体微观模拟

This study develops a survey-calibrated, path-dependent agent-based microsimulation for evaluating crime and violence reduction policies in Bolivia. A synthetic population is constructed from the 2025 Household Survey and the fourth-quarter 2025 Continuous Employment Survey using official expansion weights and cross-survey donor matching. The model combines heterogeneous agents, place-based risk, criminal adaptation, institutional capacity, community organization, and…

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A robust regression approach to synthetic control with interference

存在干扰时合成控制的稳健回归方法

Synthetic control methods are widely used for policy evaluation, but most existing approaches rule out interference among units, compromising validity when such effects are present. We develop a framework that accommodates contaminated donor pools and unknown interference patterns through two stages: factor-model adjustment for unobserved confounding, followed by robust regression in which direct and interference effects appear as a sparse outlier component. We study two…

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Mining Causality: AI-Assisted Search for Instrumental Variables

挖掘因果关系:人工智能辅助搜索工具变量

The instrumental variables (IVs) method is a leading empirical strategy for causal inference. Finding IVs is a heuristic and creative process, and justifying their validity---especially exclusion restrictions---is largely rhetorical. We propose using large language models (LLMs) to search for new IVs through narratives and counterfactual reasoning, similar to how a human researcher would. The stark difference, however, is that LLMs can dramatically accelerate this process…

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A General Design-Based Framework and Estimator for Randomized Experiments

随机实验的一般设计型框架与估计器

We describe a widely applicable design-based framework for drawing causal inference in randomized experiments. Causal effects are defined as linear functionals evaluated at unit-level potential outcome functions. Assumptions about the potential outcome functions are encoded as function spaces. This makes the framework expressive, allowing experimenters to formulate and investigate a wide range of causal questions that previously could not be investigated with design-based…

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Bayesian Neural-Net-Assisted Multi-Treatment Mixture Cure Survival Model with Application in Pediatric Oncology

贝叶斯神经网络辅助多处理混合治愈生存模型:儿科肿瘤应用

Estimating covariate-conditional treatment effects in multi-arm oncology studies is complicated when treatment arms have common distributional features and a non-negligible fraction of patients achieve long-term remission. We propose a joint mixture cure model with covariate-dependent mixtures of log-normal kernels with treatment-specific inclusions. Both linear and neural-network-assisted non-linear covariate links are proposed. Specifically, the susceptible survival…

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Partitioning Time in Target Trial Emulation

目标试验模拟中的时间划分

In target trial emulation, the treatment strategies that patients follow are inferred from the treatments they actually receive in routine care. However, in most settings, the outcome may preclude the observation of planned treatment, giving rise to immortal time bias through misclassification of treatment strategy, while markers of treatment response may influence subsequent treatment decisions, giving rise to time-varying confounding. A key step toward unbiased treatment…

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Randomization Tests in Switchback Experiments

交替处理实验中的随机化检验

Switchback experiments assign an experimental unit, such as a market or a platform, to treatment or control over successive blocks of time. Inference can be challenging because these experiments often contain only a small number of randomized blocks, while outcomes may exhibit serial dependence, seasonality, and treatment effects that persist across periods. We develop a conditional randomization test for the null of no total treatment effect that is finite-sample valid…

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Big Wins, Small Net Gains: Direct and Spillover Effects of First Industry Entries in Puerto Rico

本地收益大、净收益小:波多黎各首次行业进入的直接与溢出效应

I study how first sizable industry entries reshape local and neighboring labor markets in Puerto Rico. Using over a decade of quarterly municipality--industry data (2014Q1--2025Q1), I identify ``first sizable entries'' as large, persistent jumps in establishments, covered employment, and wage bill, and treat these as shocks to local industry presence at the municipio--industry level. Methodologically, I combine staggered-adoption difference-in-differences estimators that are…

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Graph-Split Bayesian Causal Forest for Spatial Heterogeneous Treatment Effect Estimation

图分割贝叶斯因果森林:空间异质性处理效应估计

In spatial observational studies, treatment assignment and outcomes often exhibit spatial dependence patterns, and treatment effects may vary across space and subpopulations due to both measured and unmeasured spatially structured confounders. Accounting for spatial dependence while estimating heterogeneous treatment effects (HTEs) is a central task in spatial causal inference. Causal Bayesian additive regression tree methods are popular nonparametric methods for modeling…

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Identification and efficient estimation of compliance and network causal effects in cluster-randomized trials

整群随机试验中依从效应与网络因果效应的识别和有效估计

Treatment noncompliance is pervasive in infectious disease cluster-randomized trials. Although all individuals within a cluster are assigned the same treatment condition, the treatment uptake status may vary across individuals due to noncompliance. We propose a semiparametric framework to evaluate the individual compliance effect and network assignment effect within principal stratum exhibiting different patterns of noncompliance. The individual compliance effect captures…

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