Mixed-Response State-Space Model for Analyzing Multi-Dimensional Digital Phenotypes
分析多维数字表型的混合响应状态空间模型
Digital technologies (e.g., mobile phones) can be used to obtain objective, frequent, and real-world digital phenotypes from individuals. However, modeling these data poses substantial challenges since observational data are subject to confounding and various sources of variabilities. For example, signals on patients' underlying health status and treatment effects are mixed with variation due to the living environment and measurement noises. The digital phenotype data thus…