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Large language models are increasingly used to classify text at scale. Because their outputs are stochastic, it is common to query a model several times per item and aggregate the results, and latent class models offer a principled way to convert such repeated ratings into estimates of outcome prevalence and of the model's error rates. These models assume that repeated ratings of the same item are conditionally independent given the true label. We examine this assumption…

选择偏差下恢复平均处理效应的图形规则AI 解读

Selection bias is a major obstacle toward valid causal inference in epidemiology. Over the past decade, several graphical rules based on causal diagrams have been proposed as sufficient identification conditions for addressing selection bias and recovering causal effects. However, these simple graphical rules are typically coupled with specific identification strategies and estimators. In this article, we show two important cases of selection bias that fall outside the scope…

利用处理后变量研究预测性处理效应异质性的经验分层AI 解读

Post-treatment variables (PVs), such as intercurrent events, treatment noncompliance, and behavioral responses to treatment, provide information about individuals' post-treatment responses and may help characterize heterogeneity in treatment effects on the primary outcome. This paper develops an empirical stratification framework to study the treatment effect heterogeneity across baseline-predicted PV response profiles. Specifically, we construct empirical scores from…

迈向连续处理的 R-learnerAI 解读

The R-learner is widely used in causal inference due to its flexibility and efficiency in estimating the conditional average treatment effect. However, extending the R-learner framework from binary to continuous treatments introduces a non-identifiability issue, as the functional zero constraint inherent to the conditional average treatment effect cannot be directly imposed in the R-loss under continuous treatments. To address this, we propose a two-step identification…

连续主分层的半参数局部化分析AI 解读

Principal stratification is essential for revealing causal mechanisms involving post-treatment intermediate variables, in real-world applications like surrogate marker evaluation. Principal stratification analysis with continuous intermediate variables is increasingly common but challenging due to the infinite principal strata and the nonidentifiability and nonregularity of principal causal effects. Inspired by recent research, we resolve these challenges by first using a…