Causal machine learning for high-dimensional mediation analysis using interventional effects mapped to a target trial
映射至目标试验的干预效应:高维中介分析中的因果机器学习
Causal mediation analysis examines causal pathways linking exposures to disease. The estimation of interventional effects, which are mediation estimands that overcome certain identifiability problems of natural effects, has been advanced through causal machine learning methods, particularly for high-dimensional mediators. Recently, it has been proposed interventional effects can be defined in each study by mapping to a target trial assessing specific hypothetical mediator…