Doubly robust estimators of the restricted mean time in favor estimands in individual- and cluster-randomized trials
个体与整群随机试验中治疗占优限制平均时间的双重稳健估计
Progressive multi-state survival outcomes are common in trials with recurrent or sequential events and require treatment effect estimands that remain interpretable without proportional intensity or Markov assumptions. The restricted mean time in favor of treatment (RMT-IF) extends the restricted mean survival time to ordered multi-state processes and provides such an interpretable estimand. However, existing RMT-IF methods are nonparametric, assume covariate-independent…