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模型误设下观测研究中倾向得分模型与因果估计量的应用AI 解读

Propensity score (PS) methods are widely used in observational studies to reduce confounding and estimate causal treatment effects. However, the validity of PS-based causal estimators depends heavily on correct model specification, and model misspecification may lead to substantial bias and instability. In this study, we systematically evaluate the performance of commonly used causal estimators, including response surface modeling (RSM), inverse probability weighting (IPW),…

利用倾向得分加权与分部借用幂先验增强临床试验对照组AI 解读

Borrowing external data can improve estimation efficiency but may introduce bias when populations differ in covariate distributions or outcome variability. A proper balance needs to be maintained between the two datasets to justify the borrowing. We propose a propensity score weighting borrowing-by-parts power prior (PSW-BPP) that integrates causal covariate adjustment through propensity score weighting with a flexible Bayesian borrowing approach to address these challenges…