A cautionary note for plasmode simulation studies in the setting of causal inference
因果推断中 Plasmode 模拟研究的注意事项
Plasmode simulation has become an important tool for evaluating the operating characteristics of different statistical methods in complex settings, such as pharmacoepidemiological studies of treatment effectiveness using electronic health records (EHR) data. These studies provide insight into how estimator performance is impacted by challenges including rare events, small sample size, etc., that can indicate which among a set of methods performs best in a real-world dataset.…