Instrumental Variables with Time-Varying Exposure: Dynamic Effects of Revascularization on Quality of Life
时变暴露下的工具变量:血运重建对生活质量的动态效应
This paper develops instrumental variables (IV) estimators for dynamic causal effects in randomized trials with imperfect compliance. These methods are applied to a randomized trial that assigned patients with ischemic heart disease to either an invasive treatment arm centered on revascularization or a control group meant to receive non-invasive medical therapy. As is common in such ``strategy trials,'' many participants assigned to treatment remained untreated while many…