Quantifying inconsistency in one-stage individual participant data meta-analyses of treatment-covariate interactions: a simulation study
单阶段个体参与者数据元分析中治疗与协变量交互作用的不一致性度量
It is recommended that measures of between-study effect heterogeneity be reported when conducting individual-participant data meta-analyses (IPD-MA). Methods exist to quantify inconsistency between trials via I^2 (the percentage of variation in the treatment effect due to between-study heterogeneity) when conducting two-stage IPD-MA, and when conducting one-stage IPD-MA with approximately equal numbers of treatment and control group participants. We extend formulae to…