A comparison of methods for estimating the average treatment effect on the treated for externally controlled trials
外部对照试验中处理组平均处理效应估计方法的比较
While randomized trials may be the gold standard for evaluating the effectiveness of the treatment intervention, in some special circumstances, single-arm clinical trials utilizing external control may be considered. The causal treatment effect of interest for single-arm trials is usually the average treatment effect on the treated (ATT) rather than the average treatment effect (ATE). Although methods have been developed to estimate the ATT, the selection and use of these…