A pseudo-outcome-based framework to analyze treatment heterogeneity in survival data using electronic health records
利用电子健康记录分析生存治疗效应异质性的伪结果框架
An important aspect of precision medicine focuses on characterizing diverse responses to treatment due to unique patient characteristics, also known as heterogeneous treatment effects (HTE), and identifying beneficial subgroups with enhanced treatment effects. Estimating HTE with right-censored data in observational studies remains challenging. In this paper, we propose a pseudo-outcome-based framework for analyzing HTE in survival data, which includes a list of…