Treatment persistence drives estimator performance in longitudinal causal inference based on observational data: A simulation study
处理持续性如何影响纵向观察数据中的因果估计表现
Longitudinal clinical data are increasingly available, offering opportunities to study treatment effects over time but also raising challenges related to time-varying confounding and evolving treatment decisions. We investigate how longitudinal treatment dynamics affect causal effect estimation when baseline and longitudinal methods target different causal estimands. Using a structural causal model (SCM), we simulate data with time-varying confounding, binary treatment, and…