Defining and Estimating Effects in Cluster Randomized Trials: A Methods Comparison
整群随机试验中的效应定义与估计:方法比较
Across research disciplines, cluster randomized trials (CRTs) are commonly implemented to evaluate interventions delivered to groups of participants, such as communities and clinics. Despite advances in the design and analysis of CRTs, several challenges remain. First, there are many possible ways to specify the causal effect of interest (e.g., at the individual-level or at the cluster-level). Second, the theoretical and practical performance of common methods for CRT…